Circulatory Flashcards

0
Q

Which layer of Tunica is Thicker in arteries

A

Tunica media

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1
Q

Three layers of blood vessels

A

Tunica externa, tunica media, Tunica interna

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2
Q

What two things help Venous blood return to heart

A

Respiratory pump and muscle contractions

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3
Q

Three types of capillaries

A

Continuous fenestrated discontinuous

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4
Q

Where are continuous capillaries found

A

Skin muscles CNS lungs

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5
Q

Where are fenestrated capillaries found

A

Kidneys endocrine system intestines

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6
Q

Where are discontinuous capillaries found

A

Liver spleen bone marrow

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7
Q

What makes up the formed elements of the blood

A

White blood cells red blood cells platelets

Leukocytes, erythrocytes, thrombocytes

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8
Q

What makes a plasma

A

Water proteins electrolytes antibodies and hormones

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9
Q

Three plasma proteins

A

Albumin, globulins, fibrinogen

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10
Q

Albumins function

A

Provide osmotic pressure, draw water from tissues into blood

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11
Q

Globulins function and types

A

Alpha and beta globulins transport lipids and fat-soluble vitamins. Gamma globulin’s are antibodies

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12
Q

Describe hemoglobins structure

A

For protein chains called globulins, each bound to 1 heme molecule

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13
Q

Two types of white blood cells

A

Granular leukocytes and a granular leukocytes

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14
Q

Three types of granular leukocytes

A

Neutrophils eosinophils and basophils

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15
Q

Two types of a granular leukocytes

A

Lymphocytes and monocytes

16
Q

Three functions of platelets and platelet life length

A

Release serotonin, reduced blood flow to clot area, secrete growth factors to maintain integrity of blood vessel wall

Survive 5–9 days

17
Q

Name three types of the hematopoiesis where these can occur and what each are stimulated by

A

Erythropoieses- stimulated by erythropoietin
Leukopoiesis- stimulated by cytokines
Platelet formation- stimulated
by thrombopoieten
occur in myloid tissue (red bone marrow) and lymphoid tissue

18
Q

Erythropoiesis – stages of formation

A

Erythropoietin which is released from the kidney binds to proerythroblasts > become erythroblast which becomes normoblast which becomes reticulocyte which is released into blood on third day and matures into erythrocyte

19
Q

Blood clotting – scientific name, three major mechanisms

A

Vasoconstriction, the formation of a platelet plug, the production of a web of fibrin proteins that penetrates and surrounds the platelet plug

20
Q

Describe platelet plug formation

A

Platelets exposed to collagen stick to the collagen and are bound more soundly with the help of von Willebrand’s factor. The platelets degranulate and release their secretory products which are ADP, serotonin, and thromboxane a2 – This is known as platelet release reaction. The ADP and thromboxane A2 recruit new platelets and make them sticky.

21
Q

Describe relationship between fibrin and platelet plug

A

Platelets activate clotting factors that convert fibrinogen into fibrin. The fibrinogen in the fibrin bind to binding sites on the platelets to strengthen platelet plug.

22
Q

Describe the extrinsic pathway

A

The shortcut pathway. Activated by tissue thromboplastin, clotting factor three, which activates factor seven. Factor seven then forms the seven complex which consists of factor seven, factor three, calcium and phospholipids. the factor seven complex then activated factor 10 in the common pathway

23
Q

Describe the intrinsic pathway

A

Activated by contact with negative surface. Factor seven becomes activated which activates factor 11 which activates factor nine which then forms the factor eight complex which consists of factor eight, Factor nine, calcium, and phospholipids. This then activates factor 10 in the common pathway

24
Q

Describe the common pathway

A

Activated factor 10 forms the five complex which consists of factor five factor 10, calcium, and phospholipids. This activates the conversion of prothrombin to thrombin which then activate the conversion of fibrinogen to fibrin which then with the help of factor 13 forms fibrin polymers

25
Q

Describe clot retraction

A

After fibrin binds to platelets to form plug the clock retracts to form a small tight plug. Serum is squeezed from the plug

26
Q

Describe dissolution of clots

A

Factor 12 promotes formation of kallikrein which converts plasminogen to Plasmin. Plasmin digest fibrin and dissolve the clot

27
Q

Identify the two functions of the lymphatic system

A

Protection and transport interstitial fluid back to blood and fat from small intestine into the blood

28
Q

Describe the function of lymph system

A

Lymph capillaries absorb excess interstitial fluid proteins, dead white blood cells, And fat and filters them through lymph ducts. Fluid is moved through lymph system by peristaltic waves generated by own action potential lymph ducks eventually empty into one of the two principal vessels – the thoracic duct or the right lymphatic duct. These ducks then drain the limp into the right or left subclavian vein

29
Q

Sites of lymphocyte production

A

Lymph nodes, tonsils, sinus, and spleen

30
Q

Electrical impulses travel in the heart

A

SA node to AV node to AV bundle (bundle of His)to Purkinje fibers

31
Q

EKG correlation with electrical activity in heart

A

P-wave corresponds with atrial depolarization QRS complex correlates with ventricular depolarization T-wave correlates with ventricular repolarization

32
Q

Heart sounds correlation with electrical activity of heart

A

First heart sound lub correlates with ventricular systole so the QRS complex, and second heart sound dub correlates with ventricular diastole so the t wave