MUSCARINIC REC. effects Flashcards
M1 organ?
brain
M2 organ?
heart
M3 organs?
Peripheral vasculature
Lungs
Badder
Eyes
GI
Skin
M1. Stimulation?
Memory formation, cognitive functioning
M1 inhibition?
Confusion
M2 stimulation?
Decr rate and atrial contraction
M2 inhibition?
incr. rate and contractility
M3. perif vascular. stimulation?
Smooth muscle relaxation, vasodilation, hypotension
M3. perif vascular. inhibition?
Smooth muscle contraction, vasoconstriction, hypertension
M3 lungs. stimulation?
bronchoconstriction
M3 lungs. inhibition?
bronchodilation
M3 bladder. stimulation?
detrusor contraction
M3 bladder. inhibition?
detrusor relaxation, urinary retention
M3. eyes. stimulation?
pupillary sphincter muscle contraction (miosis), ciliary muscle contraction (accommodation)
M3. eyes. inhibition?
mydriasis, cycloplegia, may precipitate acute angle glaucoma in elderly patients