Diagnostic test/prev/incid Flashcards

1
Q

Sensitivity definition?

A

the probability of a diseased person testing positive

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2
Q

Specificity definition?

A

the probability of a non-diseased person testing negative

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3
Q

PPV definition?

A

the probability that person who has a positive test, actually has the disease

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4
Q

NPV definition?

A

the probability that person who has a negative test, actually does not have the disease

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5
Q

Positive likelihood ratio definition?

A

a ratio representing the likelihood of having the disease given a positive result

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6
Q

Negative likelihood ratio definition?

A

a ratio representing the likelihood of having the disease given a negative result

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7
Q

sensitivity formula?

A

TP/ (TP+FN)

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8
Q

specificity formula?

A

TN/ (TN+FP)

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9
Q

PPV formula?

A

TP/ (TP+FP)

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10
Q

NPV formula?

A

TN/ (TN+FN)

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11
Q

+LR formula?

A

Sensitivity/ (1-specificity)

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12
Q

-LR formula?

A

(1-sensitivity)/ specificity

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13
Q

Sensitive tests have many ….

A

FP

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14
Q

Specific tests have few ….

A

FP

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15
Q

SN-N-OUT?

A

sensitive tests, if negative, rule out the disease

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16
Q

SP-P-IN?

A

specific tests, if positive, rule in the disease

17
Q

sensitivity. value approaching 100 proc. is desirable for ruling OUT DISEASE and indicates a low FN rate

A

.

18
Q

specificity. value approaching 100 proc. is desirable for ruling IN DISEASE and indicates a low FP rate

A
19
Q

What test for screening?

A

sensitivity

20
Q

what test used for confirmation after a positive screening test?

A

specificity

21
Q

increasing prevalence of disease increases ……

A

PPV

PPV varies directly to prevalence

22
Q

decreasing prevalence of disease increases ……

A

NPV

NPV varies inversely to prevalence

23
Q

LR +/- ranges?

A

LR+ > 10 and/or LR- <0,1 indicate a very usedul diagnostic test

24
Q

Incidence. definition?

A

Measure of NEW cases that develop in a population over a certain period of time

25
Q

Prevalence. definition?

A

Measure of the TOTAL number of cases (new and old) measured at a particular point in time

26
Q

Incidence. 2 points to remember?

A
  1. Measuring incidence:

a. Make sure you define the TIME PERIOD during which new cases is counted

b. Make sure you include only the population at risk of acquiring the disease

27
Q

prevalence incr –> PPV?

A

incr

28
Q

prevalence decr –> PPV?

A

decr

29
Q

prevalence incr –> NPV?

A

decr

30
Q

prevalence decr –> NPV?

A

incr

31
Q

Precision (reliability)? patikimumas. definition?

A

The consistency and reproducibility of a test.

Absence of random variation in a test

32
Q

Accuracy (validity)? pagrįstumas. definition?

A

the trueness of test measurement.

The absence of systematic erroc or bias in test.

It means how much the test results agree with the gold standard test.