Multiple Sclerosis

Question 1

Multiple sclerosis affects only which nervous system?

Answer 1

CNS (central nervous system)

Question 2

What is multiple sclerosis?

Answer 2

-chronic inflammatory demyelitating disease
-can be sucebtible by genetic background

Question 3

Having MS can trigger ?

Answer 3

infections
gut microbiota
Vit D deficiency

Question 4

Multiple Sclerosis forms what plaques?

Answer 4

Focal Demyelinating plaques (which can be located in either the brain or the spinal cord)

Question 5

Where do Focal demyelinating plaques develop ?

Answer 5

Dissemination space

Question 6

Depending on the localization of the MS lesion, will determine….?

Answer 6

-the clinical deficit.
-whether the deficit is :
*motor
*sensory
*cerebellar
*visual

Question 7

Through an MRI you can deduce the age of the lesion, meaning you determine…..?

Answer 7

Dissemination in time (how old is the lesion)

Question 8

Inflammation lesions of MS are associated with……. ?

Answer 8

Blood brain barrier

Question 9

Where does the inflammation caused by MS accumulate?

Answer 9

in the Virchow Robin Spaces of large drainage veins and meninges

Question 10

Topography of the accumulation of inflammation in the Virchow Robin Spaces of large drainage veins and meninges in cortical sulci explains ….?

Answer 10

lesions in a pregressive state of MS