Brain Tumors Flashcards
What are brain tumors?
Neoplasms arising from different cells within the central nervous system or
from systemic cancers that have metastasized to the CNS
What are the tumors coming from glial cells?
Astrocytoma,Oligodendroglioma, Glioblastoma
What are the tumors coming from neurons?
Neurocytomas,Gangliogliomas, Gangliocytomas
What are the tumors coming from meninges?
Meningioma
What are the tumors coming from choroid plexus?
Papilloma, Carcinoma
What are the tumors coming from ependyma?
Ependymoma
What are the tumors coming from pineal gland?
Pinoplastoma, Pineocytoma
What are the tumors coming from pituitary?
Adenoma
What are the tumors coming from hematologic?
primary CNS lymphoma, intravascular lymphoma
What are tumors that affect adults?
1.Glioblastoma Multiforme (most common)
2. Oligodendroglioma
3. Meningioma
4. Hemangioblastoma
5. Pituitary tumors
6. Schwannoma
What are tumors that affect children?
1.Oilocytic astrocytoma
2.Medulloblastoma
3. Ependymoma
4. Craniopharyngioma
5. Pinealoma
What are some clinical presentation of the tumors?
headches,nausea, vomiting,seizures
What are glioblastomas?
-also known as glioblastoma multiforme (GBM)
-most invasive tumors
-tumors are often devastating and rapidly fatal
-arise from hemispheric white matter typically in the frontal and temporal lobes
-Sometimes they cross the midline via the corpus callosum or anterior commissure and invade the contralateral hemisphere, which gives them a “butterfly” appearance
-areas of pseudopalisading means that cells are arranged in a “picket-fence” pattern surrounding a necrotic core
IDH-1 or IDH-2 mutation is the single most important prognostic factor in…
astrocytomas and oligodendrogliomas
What are the most common gliomas in adults?
astrocytomas and oligodendrogliomas
