Multiple Myeloma Flashcards

1
Q

Multiple Myeloma

A

cancer of plasma cells that release antibodies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

risk factors

A

FH, African descent, exposure to radiation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

signs

A
Calcium elevated
Renal problems
Anaemia (normocytic)
Bone problems
Bleeding
Infections
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

investigations

A

serum protein electrophoresis
Bence Jone proteins
rouleaux formation
Bone aspiration and biopsy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

management

A

Chemotherapy + steroid

stem cell transplantation (avoid in elderly/immunocompromised)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what would be seen on the x-ray

A

rain drop skull

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what can precipitate renal failure in myeloma

A

NSAIDs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly