Disseminated Intravascular Coagulation Flashcards
1
Q
DIC
A
abnormal regulation of clotting cascade and fibrinolysis
2
Q
causes
A
infection malignancy sepsis severe illness trauma
3
Q
signs
A
bleeding from abnormal sites:
gums, epistaxis, bleeding at cannula sites
hypotension, petechia, bruising, confusion
classic ill symptoms
4
Q
investigations
A
bloods:
thrombocytopenia
elevated D-dimer
prolonged APTT, PT
reduced fibrinogen
schistocytes can be seen
5
Q
management
A
manage underlying condition
transfusion of platelets, FFP, cryoprecipitate
6
Q
when do you transfuse for platelets
A
<10 with no bleeding
<30 significant bleeding
<100 and severe bleeding
7
Q
what determines wether cryoprecipitate should be given
A
low fibrinogen level
