Lymphoma

Question 1

Lymphoma

Answer 1

cancer of lymphocytes

Question 2

types

Answer 2

Hodgkin’s and Non-Hodgkin’s

Question 3

Hodgkin’s Lymphoma

Answer 3

occurs in patients in their 20s

RF:
HIV
EBV
autoimmune condition

signs:
spreading lymphadenopathy unilaterally
B symptoms
pain after drinking alcohol

investigations:
lymph node biopsy
Reid-Sternburg cells - bilobed nucleus and prominent eosinophilic inclusion
elevated lactate

Management:
Chemo
Radio

Question 4

Non-Hodgkin’s Lymphoma

Answer 4

occurs in older patients

RF:
HIV
EBV

types:
Burkitt - HIV, malaria, African descent
MALT lymphoma - previous H.pylori
Diffuse large B cell lymphoma

investigations:
lymph node biopsy
HIV test
elevated lactate

management:
watch and wait
chemo
ritixumab

Question 5

what is the name of staging used for this cancer

Answer 5

Ann Arbour Staging

Question 6

what type of transfusion is given in Hodgkins if needed and why is that given

Answer 6

irradiated RBCs

to avoid transfusion associated with graft versus host disease