Multiple ligation-dependent probe amplification

Question 1

This technique permits, in a few hours, relative quantification of more than 40 different nucleic acid sequences in a single reaction

Answer 1

Multiple ligation-dependent probe amplification

Question 2

What are the uses of MLPA

Answer 2

Screen for subtelomeric microdeletions, for microdeletions affecting various regions with a single large gene, such as dystrophin, or for interstitial deletions or duplications known to be responsi- ble for a range of genetic syndromes.