Introduction

Question 1

Mutations sometimes involve very large parts of the chromosome, & when these are large enough to be visible under the light microscope they are termed _____.

Answer 1

chromosome aberrations

Question 2

With routine light microscopy, the smallest visible addition or deletion from a chromosome is about _____.

Answer 2

4 Mb

Question 3

Scale of haploid DNA to average gene

Answer 3

8 km: 30 m

Question 4

Visible abnormality usually involves many _____.

Answer 4

contiguous genes

Question 5

Abnormalities of chromosome where the somatic cells contain an abnormal number of normal chromosomes.

Answer 5

Numerical abnormalities

Question 6

Abnormalities of chromosome where somatic cells contain one or more abnormal chromosomes.

Answer 6

Structural aberrations

Question 7

T/F. Chromosomal aberrations may involve either the sex chromosomes or the autosomes and may occur either as a result of a germ cell mutation in the parent or a more remote ancestor, or as a result of somatic mutation, in which case only a proportion of cells will be affected.

Answer 7

True