Mucosa Colour Changes Flashcards

1
Q

what can cause oral white lesions

A

smoking/ frictional changes
lichen planus
candidal leukoplakia
carcinoma

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2
Q

why are white lesions white

A

the red colour of mucosa comes from the connective tissues - where the blood vessels are
when there is thickening of the mucosa or keratin there is less visibility of blood so appears more white

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3
Q

what is leukoplakia

A

a white patch which cannot be scraped off or attributed to any other cause

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4
Q

what are Fordyce’s spots

A

benign, variation of normal with no malignancy potential
white bumps on the buccal mucosa

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5
Q

where might you find frictional keratosis

A

in patients who grind their teeth on the buccal mucosa along the occlusal plane

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6
Q

why might smokers get frictional keratosis

A

trauma from thermal gases

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7
Q

what is hereditary keratosis

A

not traumatic - occurs in areas not subject to trauma

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8
Q

what is an example of hereditary keratosis

A

white sponge naevus - fluid accumulating between the epithelium

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9
Q

what is idiopathic keratosis

A

clearly defined white lesion with normal mucosa surrounding

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10
Q

what must you do with idiopathic keratosis lesions

A

biopsy them

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11
Q

what medications might cause white lesions

A

aspirin - aspirin burns

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12
Q

what are the three types of infective causes that contribute to white patches

A

pseudomembranous acute candidiasis
denture associated chronic candidiasis
herpes simplex

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13
Q

what does pseudomembranous suggest

A

they membrane can be scraped off and leaves a red inflamed area underneath

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14
Q

how does herpes simplex appear as white lesions

A

they appear as white vesicles on the lips

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15
Q

when to refer a white lesion

A

if lesion is becoming more raised and thickened
if lesion is without cause
take photograph with referral

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16
Q

why are red lesions red

A

blood flow increases due to inflammation and dysplasia
there is also reduced thickness of the epithelium

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17
Q

what is erythroplakia

A

a red patch which cannot be attribute to any other cause

18
Q

what is more of a concern of malignancy leukoplakia or erythroplakia

A

erythroplakia

19
Q

does erythroplakia require biopsy

A

yes

20
Q

what are red/blue lesions

A

fluid in connective tissue

21
Q

what does dark red/blue lesions suggest

A

slow moving blood - varicosities

22
Q

what does light blue lesions suggest

A

clear fluid, saliva or lymph

23
Q

what would be a lesion that can increase and decrease in size

A

a vascular lesion

24
Q

what is a tell-tale sign of a malignancy with regards to size

A

it will only increase in size

25
Q

what could a blue round lesion on the labial mucosa be

A

haemangioma

26
Q

what are the three types of vasculitic diseases (connective tissue disease)

A

large vessel disease
medium vessel disease
small vessel disease

27
Q

what is an example of large vessel disease

A

giant cell (temporal) arteritis

28
Q

what are two examples of medium vessel disease

A

polyarteritis nodosa
kawasaki disease

29
Q

what is an example of small vessel disease

A

granulomatosis with polyangitis

30
Q

what causes external pigmented lesions

A

tea, coffee, chlorhexidine, bacterial overgrowth

31
Q

what causes internal pigmented lesions

A

melanin producing melanocytes

32
Q

what is reactive melanosis

A

normal number of melanocytes producing increased amounts of melanin

33
Q

what is a naevus

A

melanocyte is increased in number all producing normal levels of melanin

34
Q

what can be causes of localised brown or black lesions

A

amalgam
melanotic macule
melanotic naevus
malignant melanoma
Kaposi’s sarcoma

35
Q

what can be causes of generalised brown or black lesions

A

racial/ familial
smoking
drugs
addison’s disease - raised ACTH conditions

36
Q

what drugs can cause brown or black lesions

A

oral contraceptive pill
tetracyclines

37
Q

what is the link between ACTH and melaninn

A

raised ACTH levels cause melanocytes to make more melanin

38
Q

how to determine to refer mucosal pigmentation

A

is it easily explained
is it increasing in size, colour or quantity
any new systemic problems

39
Q

what are the attributes of a melanoma

A

variable pigmentation
irregular outline
raised surface
symptomatic (itch and bleeds)

40
Q

what is the purpose of biopsies

A

identifies or excludes malignancy
identifies dysplasia
identifies other disease

41
Q
A