Lichen Planus 1 Flashcards
what does reticular lichen planus present as
lazy pattern of white lesions around the mucosa
what does atrophic/ erosive lichen planus present as
the lesion has destroyed the epithelium
can the lichen planus lesions be cured
no - treatment is based on treating symptoms
what is lichen planus
T cell infiltrate into basement membrane area of the connective tissue
what is seen in cells of lichenoid reaction
chronic inflammatory cell infiltrate
saw tooth rete ridges
basal cell damage
patchy acanthosis
parakeratosis
what occurs at a cell level in lichenoid reactions
lymphocytes attracted to the area
langerhans cells in epithelial present antigen that is activating immune response
immune response tries to remove irritation which causes change in epithelium
what are some causes of lichen planus
genetic predisposition
physical and emotional stress
injury to skin
what is isomorphic response
where skin is scratched after surgery causing a lichen planus reaction
what is an isotopic response with regards to lichen planus
when a localised skin disease (herpes zoster) is involved
what drugs can cause a lichenoid rash
gold, beta blockers, ACE inhibitors
what is wickem’s straie
pattern of lichenoid lesions
what is an oral symptom of lichen planus
sensitivity to hot or spicy foods - thinning of epithelium caused by atrophic changes by lichen planus
where does lichen planus affect the most
most often buccal mucosa
gingivae
tongue
what is a lesion called if it looks like lichen planus but solely affects the gingiva
desquamative gingivitis
where is an easy biopsy site for lichen planus
buccal mucosa
