Drugs in Oral Medicine Flashcards

1
Q

what is chlorhexidine mouthwash an example of

A

non-steroidal topical treatment of oral mucosal lesions

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2
Q

what is benzdamine mouthwash an example of

A

non-steroidal topical treatment of oral mucosal lesions

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3
Q

what is hydrocortisone mucoadhesive pellet

A

a steroidal based topical treatment of oral mucosal lesions

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4
Q

how does hydrocortisone mucoadhesive pellets work

A

allow tablet to dissolve over ulcer

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5
Q

what are topical steroidal treatments for oral mucosa lesions

A

hydrocortisone mucoadhesive pellets
betamethasone mouthwash
beclamethasone metred dose inhaler

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6
Q

why do you have to supply a tailored information leaflet for betamethasone mouthwash and beclamethasone metred dose inhaler

A

they are unlicensed medicines

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7
Q

what are the steps for using betamethasone mouthwash

A

2 tablets (2x0.5mg) in 10ml water and rinse for 2 mins twice daily
DO NOT swallow and no eating for 30 min

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8
Q

from what age can betamethasone mouthwash be used

A

12 years

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9
Q

why must the beclomethasone metred dose inhaler be a pressurised device and not a breath activated device

A

so the patients doesn’t breathe in the steroid - want it to sit on the mucosa

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10
Q

what systemic treatment can be used to treat oral mucosal lesions

A

disease modulators
steroids

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11
Q

what is an example of a disease modulator used systemically to treat mucosal lesions

A

colchicine

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12
Q

what is an example of a steroid used to systemically treat mucosal lesions

A

prednisolone

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13
Q

why might prednisolone be given for oral lesions

A

for intermittent troublesome ulcers
high dose short duration prescription of 30mg for 5 days

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14
Q

what are risks of systemic steroids

A

adrenal suppression
cushingoid features
osteoporosis risk
peptic ulcer risk
mood/ sleep alteration

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15
Q

what are examples of immune suppressants

A

hydroxychloroquine
azathrioprine
mycophenolate

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16
Q

what are two examples of immunotherapy

A

adalimumab
enterecept

17
Q

what preparation does the patient have to go through before systemic immunomodulatory treatment (give three examples)

A

blood borne virus screen
FBC
electrolytes
liver function
thiopurine methyltransferase
zoster antibody screen
EBV
chest X-ray
cervical smear up to date
pregnancy

18
Q

what risks should the patient be told about when planning immunomodulatory treatment

A

short term - acute drug reaction
long term - cancer risk increased
effective contraception must be used

19
Q
A