MSK Flashcards
Main risk factors of Osteoporosis
Female (post menopause)
Low BMI
Long term steroids (inc cushings)
Dx osteoporosis
FRAX score
DEXA scan
T scores for DEXA scan
> -1 Normal
-1 to 2.5 osteopenia
<2.5 osteoporosis
Components of FRAX score
TFT
Bone profile
Bone turnover (CTX)
Mx osteoporosis
Conservative
Bisphosphonates (alendronates SEs GORD + osteonecrosis of jaw) Take on empty stomach, sit upright, wait 30 mins before eating.
Features of OA on XRay
Cyst formation
Osteophyte formation on joint edge
Narrowing of joint space
Sclerosis of subchondral bone
Mx OA
Conservative, weight loss + physio
1st - analgesia, topical nsaid + paracetamol
2nd - Oral NSAIDs + PPI + topical capsaicin
IA corticosteroids
Partial/total joint replacement
Risk factors of RA
Female, Family history (HLA DR4)
RA Dx
Rheumatoid factor (Present 70%)
anti-CCP antibodies (more specific)
Ix RA
Disease activity score (>5.5 need for biologics -mabs)
Normocytic anaemia of chronic disease
ESR/CRP elevated
Joint XR
Subluxation
Osteoporosis juxta articular
Loss of joint space
Erosions of periarticular space
RA Mx
Smoking cessation
Acute flare, NSAIDS + PPI
Glucocorticoids/sterois IM methylprednisolone
Chronic maintenance
1. Methotrexate
Sulfalazine
Hydroxychloriquine
Anti-TNF drugs (e.g. infliximab)
Commonest organisms in SA
Overall Staph aureus
young adults Neisseria gonhorroea
Children Strep pneumoniae or H influenza
Ix SA
Aspirate
MC&S
Crystal microscopy
Mx SA
Washout
IV Abx 2g fluclox QDS 2 wks
PO Abx for 4 weeks
Features of Gout
Monosodium Urate monohydrate crystals
Chronic hyperuricaemia (uric acid)