MSK

Question 1

Which antibodies are significant in SLE?

Answer 1

ANA and anti-dsDNA

Question 2

muscle stiffness and raised inflammatory markers?

Answer 2

PMR

Question 3

Typical patient for PMR:

Answer 3

> 60, rapid onset (<1 month), aching, morning stiffness in proximal limb muscles

raised inflammatory markers e.g. ESR
creatine kinase and EMG normal

Question 4

Treatment for PMR:

Answer 4

prednisolone 15mg/od

Question 5

Radiological features of ankylosing spondylitis?

Answer 5

sacroiliitis
squaring of lumbar vertebrae
bamboo spine
syndesmophytes
apical fibrosis

Question 6

Most common causes of drug induced lupus:

Answer 6

procainamide

hydralazine

Question 7

Treatment for systemic lupus erythematosus:

Answer 7

Hydroxychloroquine

NSAIDs + sunblock

Question 7

Treatment for systemic lupus erythematosus:

Answer 7

Hydroxychloroquine

NSAIDs + sunblock

Question 8

Ankylosing spondylitis features:

Answer 8

"A's": 
apical fibrosis
anterior uveitis
aortic regurgitation
achilles tendonitis
AV node block
amyloidosis

Question 9

Ankylosing spondylitis features:

Answer 9

"A's": 
apical fibrosis
anterior uveitis
aortic regurgitation
achilles tendonitis
AV node block
amyloidosis

Question 10

Where does gout most likely affect?

Answer 10

first metatarsophalangeal joint

Question 11

What is CREST syndrome?

Answer 11

subtype of limited systemic sclerosis:

Calcinosis, Raynaud’s, oEsophageal dysmotility, Sclerodactyly, Telangiectasia