MSD Flashcards

1
Q

anterior corticospinal tract

A

medial

control posture, running, walking

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2
Q

lateral cotricospinal tract

A

lateral
control distal limbs
associated with goal directed mvmts

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3
Q

pyramidal motor system

A

originates in motor cortex

control of delicate muscle mvmts

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4
Q

extrapyramidal system

A

originates in basal ganglia

more crude and supportive mvmts

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5
Q

UMN lesion affect

A

UMN lesion affect extensors in upper extremities

flexors in lower extremities

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6
Q

UMN & LMN lesions

A

UMN- increased tone, hyperactive reflexes

LMN-decreased tone, hyporeflexia

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7
Q

myasthenia gravis

A

autoimmune- disrupt nerve signals to muscles

tyrosine kinase

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8
Q

crisis in MG

A

when PT is unable to swallow, clear secretion, breathe

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9
Q

Parkinsons

A

rhythmic tumors, slowness in mvmts, rigid muscles, loss of postural reflexes, diminished substancia nigra

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10
Q

dominant PD

A

formation of lewy bodies

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11
Q

recessive PD

A

mutation in gene parkin

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12
Q

pharm treatment of PD

A

dopaminergic drugs, L-dopa
bromocriptine
anticholinergic drugs
MOA inhibitor

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13
Q

deep brain stim

A

inactivating parts of the brain without destroying others

electrodes block impulses that cause tremors

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14
Q

huntingtons

A

inherited- chromosome 4
degeneration of neurons in basal ganglia
decrease in GABA & acetylcholine

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15
Q

treatment for Huntington’s

A

no cure

chlorpromazine- SM relaxant

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16
Q

ALS

A

glutamate- excitatory neurotransmitter accum to toxic concentration
environmental toxins
abnormal immune system

17
Q

ALS affects motor neurons in 3 locations

A

LMN in spinal cord
motor nuclei in brain
UMN in cerebral cortex

18
Q

treatment for ALS

A

anti glutamate drug- decrease accum

19
Q

MS

A

demyelinating disease
yellow patches of myelin destruction
occur in white matter

20
Q

progressive relapse

A

steady decline w superimposed attacks, no remission

21
Q

secondary progressive

A

gradual neurological deterioration

with or without superimposed attacks

22
Q

primary progressive

A

steady increase w no attacks

older pt

23
Q

relapsing remitting

A

least disability - most common

stable course between relapses

24
Q

diagnose MS

A

IgG high in CSF

25
Q

treatment for MS

A

diazepam
interferons
plasmapheresis
corticosteroids