MS Medications Flashcards
Beta-Interferons: Common Drugs
Interferon beta-1a (Avonex, Rebif), interferon beta-1b (Betaseron)
Beta-Interferons: Mechanism of Action
Modulates immune response to reduce frequency of relapses and slow progression of MS.
Beta-Interferons: Contraindications
Hypersensitivity, severe liver disease, pregnancy.
Beta-Interferons: Safety Considerations
Monitor liver function tests, injection site reactions, flu-like symptoms, and depression.
Monoclonal Antibodies: Common Drugs
Natalizumab (Tysabri), ocrelizumab (Ocrevus)
Monoclonal Antibodies: Mechanism of Action
Binds to specific antigens on immune cells, reducing inflammation and demyelination in MS.
Monoclonal Antibodies: Contraindications
Active infections, history of progressive multifocal leukoencephalopathy (PML), hypersensitivity.
Monoclonal Antibodies: Safety Considerations
Monitor for infusion reactions, signs of infection, and PML (neurological changes).