Movement Of Molecules Across The Membrane Flashcards

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1
Q

What’s a fluid mosaic model

A

A model that describes the structure of the cell membrane

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2
Q

LEARN HOW TO LABEL THE PHOSPHOLOID BIYLAER

A
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3
Q

What do regions of hydrophobic R groups allow

A

String hydrophobic interactions that hold integral membrane proteins within the phospholipid bilayer

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4
Q

What do integral membrane proteins do

A

-Interact extensively with the hydrophobic region of membrane phospholipids
-some are transmembrane proteins so they spam the entirety of the cell membrane

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5
Q

What are peripheral membrane proteins

A

Have Hydrophilic R groups on their surface and are bound to the surface of membrane mainly by ionic and hydrogen bond interactions

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6
Q

What do many peripheral membrane proteins do

A

Interact with the surfaces of integral membrane proteins

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7
Q

What is the phospholipid bilayer

A

Is a barrier to ions and most uncharged polar molecules

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8
Q

How to small molecules pass through the bilayer

A

Oxygen and c02 pass through by simple diffusion

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9
Q

What is facilitated diffusion

A

The passive transport of substances across the membrane through specific transmembrane proteins

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10
Q

Why do different cell types have different channels and transporter proteins

A

To perform specialised functions

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11
Q

What are channels

A

Multi subunit proteins with the subunits arranged to form water filled pores that extend across the membrane

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12
Q

What are most channel proteins

A

Highly selective meaning they let very few types of molecules pass through

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13
Q

What do some channel proteins do

A

They are gated and change conformation to allow or prevent diffusion

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14
Q

What are ligand gated proteins controlled by

A

The binding of signal molecules

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15
Q

What are voltage gated channels controlled by

A

Changes in ion concentration

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16
Q

What do transporter proteins bind to and undergo

A

They bind to specific substance to be transported an undergo a conformational change to transfer the solute across the membrane

17
Q

Why do transporters alternate between two conformations

A

So that the binding site for a solute is sequentially exposed on one side of the bilayer then the other

18
Q

What does active transport use

A

Pump proteins that transfer substances across the membrane against their concentration gradient

19
Q

What are pumps that mediate active transport

A

Transporter proteins coupled to an energy source

20
Q

What is required for active transport

A

A source of metabolic energy

21
Q

What do some active transport proteins do

A

Hydrolyse ATP directly to provide the energy for the conformational change required to move substances across the membrane

22
Q

What is ATP hydrolysed by in active transport

A

ATPases