Eye Flashcards

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1
Q

LEARN HOW TO LABEL DIAGRAM

A
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2
Q

What’s the retina

A

Area within the eye that detects light and contains two types of photoreceptor cells

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3
Q

What are the two types of photoreceptor cells in the retina

A

Rods and cones

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4
Q

What do rods and cones do

A

Rods-function I’m dim light but do not allow colour perception
Cones- responsible for colour vision and only function in bright light

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5
Q

How are the photoreceptors formed in the eye

A

The Light sensitive molecule retinal is combined with a membrane protein opsin to form the photoreceptos

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6
Q

In rod cells what is the retinal opsin complex called

A

Rhodopsin

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7
Q

What does retinal and rhodopsin do

A

Absorbs a photon of light and rhodopsin changed conformation to photoexcited rhodopsin

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8
Q

What amplifies a signal

A

A cascade of proteins

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9
Q

What does photoexcited rhodopsin do

A

Activates a G-proteins called transducin which activates the enzyme phosphodiesterase (PDE)

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10
Q

How many G-proteins does a single photoexcited rhodopsin activate

A

Hundreds

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11
Q

What does each activated G-protein activate

A

One molecule of PDE

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12
Q

What does PDE do

A

Catalyses the hydrolysis of a molecule called cyclic GMP (cGMP)

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13
Q

What does each active PDE molecule break down

A

Thousands of cGMP molecules per second

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14
Q

What effects the ion concentration in the membrane of rod cells

A

The reduction of cGMP concentration as a result of its hydrolysis

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15
Q

What happens when ion channels in the membrane of rod cells close

A

Triggers nerve impulses in neurons in the retina

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16
Q

What does a high degree of amplification allow rod cells to do

A

Respond to low intensities of light

17
Q

In cone cells how are different colours produced

A

Different forms of opsin combine with retinal to give different photoreceptor proteins each with a maximal sensitivity to specific wavelengths e.g red blue green

18
Q

What’s step 1 of cone and rod procedure

A

Light stimulation of rhodopsin leads to activation of a G-protein called transducin

19
Q

What’s step 2 of cone and rod procedure

A

Activated G-protein activates phosphodiesterase (PDE)

20
Q

What’s step 3 of cone and rod procedure

A

PDE hydrolysis cGMP reducing its concentration

21
Q

What’s step 4 of cone and rod procedure

A

This leads to closure of Na+ channels