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CS III/1 > Movement Disorder > Flashcards

Movement Disorder Flashcards

1
Q

Parkinson’s

A

Degenerative disorder of CNS leading to loss of DA

Depigmentation of SN pars compacta

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2
Q

Parkinson’s TX

A

Add DA to system
Levodopa/carbidopa
Tox - motor fluctuations, dystonia, chorea, confusion, psychosis

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3
Q

Neuroprotection in Parkinson’s

A

No agent proven to work

Selegiline - not effective

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4
Q

Parkinson TX of symptoms

A

Depression - amitriptylline
Psychosis - clozapine
Dementia - donepezil and rivastigmine

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5
Q

Essential Tremor TX

A

Propranolol and Primidone are first line agents

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6
Q

Huntington Disease

A

CAG triplet repeat on chromosome 4

Huntington’s is excess of motion

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7
Q

Drugs for Chorea

A

Tetrabenzine - lower monoamines (DA)

Alternative - olanzapine, risperidone, fluphenazine

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CS III/1 (14 decks)

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