Movement 4 Flashcards
two aspects of area 6?
premotor area
supplementary motor area
-pre-SMA
-SMA proper
describe premotor area
uses sensory input to guide movement
describe SMA proper
plans movements guided by memory
describe pre-SMA
learns new motor sequence
PMC is aka
M1/Area 4
inputs outputs of PMC
area six
somatosensory areas 1/2/3
output: upper motor neuron
function of PMC
controls movement. only active when initiating movement
does cerebellum damage cause issues to the ipsilateral or contralateral side?
ipsilateral - below the decussation
describe vestibulocerebellum
- uses vestibular and proprioceptor info to adjust balance and posture
- damage:compensatory posture strategies; issues with balance/posture
describe cerebrocerebellum
-input is the cerebral cortex, so involved in the planning and learning of movement
describe the spinocerebellum
- inputs are the spinal cord and a motor copy of the movement from the motor cortex
- controls movement in progress, can regulate movement by modulating descending commands
damage to cerebrospinocerebellum?
ataxia: uncoordinated/inaccurate movement
dysmergia: decomposition of synergestic multi joint movement
dysmetria: lack of coordination, resulting in overshoot or undershoot
the 4 nuclei of the basal ganglia?
striatum
globus pallidus
subthalamic nucleus
substantia nigra
direct pathway acronym and thing
cute silly girls pee in silly napkins while reciting verbs
cortex + striatum - GPi /Nr + VLo +
positive feedback, facilitates cortex
indirect pathway acronym and thing
cute silly girls pee and eat steak tonight while peeing in silly napkins and reciting verbs.
…striatum - GPe - STN + GPi/SNr …
negative feedback, inhibits cortex.
Discuss dopamine - where its produced, receptors
made in substantia nigra
excitatory receptors in striatum of direct pathway, increasing facilitation; and inhibitory receptors in the striatum of the indirect pathway, increasing inhibition.
describe hyperkinetic disorders
underactivity of indirect pathway leading to more movement. eg parkinsons disease, akinesia (being unable to initiate movement)
describe hypokinetic disorders
overactivity of indirect pathway leading to less movement. eg. huntingtons disease and dyskinesia (involtunary movement)
relation of parkinsons disease to the substantia nigra
damage –> less dopamine –> less activity of direct, more activity of indirect –> less movement
treatment of parkinsons
increasing dopamine levels via less reuptake…
surgically stimulating the subthalamic nucleus and GPi