Motor Tracts Flashcards

1
Q

Where do UMNs arise from? Where are they contained?

A

W/in cerebral cortex or brain stem

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2
Q

What do the axons of UMNs synapse w/?

A

W/ LMN or interneurons of SC

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3
Q

What are LMNs?

A

Directly innervate skeletal m.

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4
Q

Where is the cell body of LMNs?

What do they synapse with?

A

Cell body in SC or brainstem

Synapse w/ Sk. M.

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5
Q

What are the two types of lower motor neurons?

A

Gamma and alpha

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6
Q

Where do gamma motor neurons project to?

A

Intrafusal fibers in muscle spindle

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7
Q

Where do alpha motor neurons project to?

A

Extrafusal skeletal muscles

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8
Q

Are alpha or gamma motor nuerons bigger?

A

Alpha

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9
Q

What are Cranial ns? LMNs or UMNs?

A

LOWER MOTOR NEUROSN

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10
Q

What is the direct somatic motor pathway?

A

Cerebral cortex -> SC -> muscles

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11
Q

Why does the direct pathway send some signals down to the brainstem?

A

To help modulate INDIRECT pathways

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12
Q

Name a few places where indirect pathways synapse.

A
Brainstem
Basal ganglia
Thalamus
Reticular formation 
Cerebellum
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13
Q

Where is the primary motor cortex?

What does it do?

A

In precentral gyrus (area 4)

Initiates voluntary movement (r. Side controls left side of body)

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14
Q

Are the neurons in the primary motor cortex UMNs or LMNs?

A

UMNs

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15
Q

Why are muscles represented unequally on homunculus?

A

Represented according to number of motor units

Those with more motor units need more cortical area

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16
Q

What is the blood supply to the

Lower limb on homunculus?

A

ACA

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17
Q

What is the blood supply to the

Hands/fingers on homunculus?

A

MCA

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18
Q

What is the blood supply to the

Face on homunculus?

A

MCA

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19
Q

Which lobes does the PCA supply?

A

Occipital and temporal lobes

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20
Q

What does the medial corticospinal tract do?

How is this tract different than the lateral?

A

Postural ms. And proximal movements

Neck, shoulder and trunk muscles

does NOT CROSS in Medulla

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21
Q

What does the lateral corticospinal tract do?

A

Limb muscles

Fractionation - finger movements

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22
Q

What is the pathway of the LCST?

A

Cell bodies in cortex
—> thru posterior limb of internal capsule
—> CST tract
—> thru cerebral peduncles
—> thru anterior pons
—> pyramids in medulla
Fibers CROSS in pyramids
—> descend in lateral column of SC (LCST)
—> Synapse with LMNs in anterior horn of spinal cord

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23
Q

How is CST oriented in the

posteiror limb of the internal capsule?

Cerebral peduncles?

Pyramids?

LCST?

A

Arms above, legs below

Arms middle, legs lateral

Arms middle, legs lateral

Arms middle, legs lateral

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24
Q

What is the blood supply to the

posterior limb of the internal capsule?

A

Lenticulate striate a

Anterior choroidal as

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25
What is the blood supply to the Cerebral peduncles?
P1 from PCA
26
What is the blood supply to the Pons?
Paramedian branches of basilar AICA Long circumferential
27
What is the blood supply to the pyramids in medulla?
Sulcal branches of ASA
28
What is the blood supply to the LSCT in SC?
Arms = medial = ASA Legs = lateral = PSA
29
Where does the CBT arise from? Where does it descend to?
Ventral part of cortical area 4 Brainstem
30
What does the CBT influence?
Influences muscles innervated by CNs that have motor nuclei | 5, 7, 9, 10, 11, 12
31
Where do the axons of CBT cross?
At pyramidal decussation
32
What are the neurons in the CBT, UMNs or LMNs?
UMNs
33
What is the pathway of the CBT?
``` Ventral art of cortical area 4 —> thru GENU of internal capsule —> CBT, —> passes thru cerebral peduncles —> thru anterior pons (CN 5 and 7) —> pyramids, cross —> thru upper medulla (CN 9, 10, 12) —> SC ```
34
What kind of input does CN 5 have at pons?
Bilateral input
35
What kind of input does CN 7 have at one by CBT?
Bilateral to forehead Contralateral to lower face
36
What kind of input does CN 12 get at upper medulla?
Bilateral BUT MOSTLY contralateral
37
What kind of input does Nucleus ambiguus get?
Bilateral BUT | MOSTLY CONTRALATERAL
38
What kind of input does CN 11 get? Why?
Ipsilateral Bc it stays with medial corticospinal tract
39
What happens if there is damage to CBT, ABOVE the pons?
Ms. Of mastication are ok-bilateral Ms. Of forehead are ok -bilateral Contralateral Lower face will droop
40
What happens if there is CBT damage AT the level of the Medulla?
Palate ms weak on contralateral side Uvula points toward lesion in CBT (away from a lesion to cn 10) Tongue point away from lesion in CBT (Toward CN 12 lesion)
41
What happens if there is damage to the CBT at SC?
Shoulder droops ipsilaterally to lesion
42
Where are LMNs found in the SC?
Anterior horn
43
Where do LMNs project to if they are Medial? Lateral?
Medail to axial ms. Lateral to limb ms.
44
What do Ventral LMNs project to?
Extensor ms.
45
What do dorsal LMNs project to?
Flexor ms.
46
How do indirect pathways activate?
Tonically activate antigravity and axial LMNs
47
What are the medial indirect UMN tracts?
``` TST Medial Reticulospinal Lateral Vestibulospinal Medial vestibulospinal Medial CST (the modulating fibers to Indirect) ```
48
What are the lateral indirect UMN tracts?
Rubrospinal Lateral reticulospinal Lateral CST (modulating fibers to indirect)
49
What do medial LMNs get input from?
From all medial indirect UMNs
50
What do lateral LMNs get input from?
From all lateral indirect UMN tracts
51
Medial Vestibulospinal spinal tract: What kind of tract? Goes from and ends where? Function?
Medial indirect Medial vestibular nuclei to Cervical and thoracic levels of SC Coordination of head movements (neck and shoulder ms.)
52
Lateral Vestibulospinal spinal tract: What kind of tract? Goes from and ends where? Function?
Medial indirect Lateral vestibular nuclei to SC’s ipsilateral LMNs innervating postural ms. And limb EXTENSORS Do extension against gravity (Will see active in decerebrate posture)
53
Medial Reticulospinal tract: What kind of tract? Goes from and ends where? Function?
Medial indirect Pontine reticular formation to SC’s ipsilateral LMNs innervating postural ms. And limb EXTENSORS Facilitate postural reflexes
54
Lateral Reticulospinal spinal tract: What kind of tract? Goes from and ends where? Function?
Lateral indirect Medullary RF to SC Excites FLEXOR MNs and INHIBITS EXT. inhibits spinal segmental reflexes
55
Tectospinal tract: What kind of tract? Goes from and ends where? Function?
Medial indirect Superior colliculus to Upper SC Coordinates head w/ eye movements
56
Rubrospinal tract: What kind of tract? Goes from and ends where? Function?
Lateral indirect Red nucleus in midbrain to SC Innervates upper limb FLEXORS
57
Corticospinal tract: Function?
Fine motor control of hand
58
Corticobulbar tract: Function?
Control of muscles of face, chewing, speech and swallowing
59
What are Lower Motor Neuron sings?
``` Flaccid paralysis Wasting or atrophy Hyporeflexia Areflexia Hypotonia Denervation hypersensitivity w/ fasciculations ```
60
What are Upper Motor Neuron signs?
Loss of distal extremity strength and dexterity Babinski sing Pronator drift HYPERtonia Spasticity Hyper-reflex is/Clonus Clasp knife phenomenon (sudden collapse at end of ROM)
61
What lesions cause a LMN sing?
Lesions to CNs 3-7, 9-12, and peripheral ns.
62
What is UMN syndrome?
Combo loss of: CST & loss of regulation from CST’s indirect pathways to brainstem
63
What is spasticity? What characterizes it?
UMN lesion Rate dependent resistance And Collapse of resistance at end of ROM
64
What is Rigidity? What characterizes it?
Basal ganglia disease Not rate or force dependent Constant thru out ROM (lead pipe or plastic like)
65
How can you tell where a LMN lesion is?
Clinical signs on same side as leasing and at exactly the level involved
66
How can you tell where a UMN lesion is?
Above lower medulla, clinical signs = contralateral In SC = clinical signs ipsilaterally
67
For a spinal cord lesion where will a UMN lesion present?
Below the level of lesion
68
What is Decorticate posture caused by? What characterizes it?
Lesion above red nucleus Thumb tucked under flexed fingers in fisted position Pronates forearm Flexion at elbow Lower extremity in extension w/ foot inversion
69
What is Decerebrate posture caused by? What tracts are still okay? What characterizes it?
Lesion below and involving Red Nucleus Reticulospinal and vestibulospinal = extensors Upper extremity is pronates and extended Lower extremity is in extension
70
What is Medial Medullary syndrome caused by? What does if affect and how does it present?
Sulcal branches of ASA stroke Pyramid - contralateral UMN signs ML (posterior columns) - contralateral loss of sensation to body CN 12 - LMN , tongue toward side of cn12 lesion
71
What is Lateral Medullary syndrome caused by? What does if affect and how does it present? What is another name for it?
PICA stroke ALS - contralateral loss of pain and temp Spinothalamic - ipsilateral loss of pain and temp to face Vestibular nuclei - vertigo, nystagmus Restiform body - ipsilateral ataxia Hypothalamic spinal tract sympathetic - ipsilateral horner’s Wallenburgs syndrome
72
If you see.... Loss of pain and temp to body contra Loss of pain and temp to face ipsi ..... How can you tell if it is lower pons or medulla?
If it is in, Lower pons = cns 6 and 7 hit Medulla = Nucl. Ambiguus hit = trouble swallowing, hoarse voice etc.
73
What is Weber syndrome caused by? How does it present?
P1 of PCA or Uncal herniation of midbrain CST affected = contra loss of motor (hemiplegia) CBT affected - contralateral drooping of face CN 3 affected - Oculomotor palsy
74
What happens if there is a complete transection of the SC?
All sensation 1 or 2 levels below lesion lost No bladder or bowel control Spinal shock ==> no DTRs
75
What happens 6 weeks after a trauma causing complete transection of the SC?
UMN signs at levels below lesion LMN signs at level of lesion
76
What happens from a hemisection of SC (Brown Sequards)?
ALS hit - contralateral loss of pain and temp to body GF/CF hit - ipsilateral loss of sensation CST hit - ipsilateral loss of motor UMNs signs ipsilaterally LMN signs at level of lesion
77
What is syringomyelia caused by? What are the characteristics of it?
Formation of cysts w/in central canal of SC Affects AWC first = ALS = pain and temp lost bilaterally (cape like pattern) If Ant. Horns affected= LMN signs If LCST affected = arms first to be affected
78
Where is syringomyelia most common at? What is it highly associated with?
C4, C5 Chiari type 1
79
What is anterior cord syndorme? What can cause this?
Compression or damage to anterior part of SC Infarction of ASA, intervetebral disc herniation and radiation myelopathy
80
What is central cord syndrome? What can cause this?
Compression or damage to central portion of SC Due to cervical hyperextension, or Syringomyelia
81
What is polyneuropahty? How does the sensory loss distribution present? Who is this commonly seen in?
Involvement of sensory, motor and autonomic axons from distal to proximal due to dying back or impaired axonal transport or demyelination Stocking/glove distribution of sensory loss Patients w/ diabetes mellitus
82
What is Amyotrophic lateral Sclerosis? Presents w/?
Destruction of somatic motor neurons (UMNs, brainstem and SC LMNs) Paresis, hyperstiffness, hyper reflex is, babinski’ s sign, atrophy, fasciculations, fibrillation Difficulty breathing, swallowing, speaking
83
What is spastic cerebral palsy?
Movement dysfunction due to abnormal Supra spinal influences, failure of normal neuronal selection and consequential aberrant msucle development
84
What are the motor disorders assoc. w/ spastic cerebral palsy?
``` Paresis Abnormal tonic stretch reflexes Reflex irradiation Lack of postural preparation prior to movement Abnormal co-contraction of muscles ```
85
What is Central Seven palsy? How does it present
Lesion of the CBT involving CN 7 Forehead will still be able to wrinkle Contralateral face will droop
86
Why does centralseven palsy present the way it does?
Bc Ms. of upper face are controlled bilaterally from both hemispheres Muscles of lower face are controlled ONLY by CONTRA hemisphere
87
What is Bell’s palsy?
Ipsilateral flaccid paralysis of lower AND upper face