Motor Flashcards
negative feedback tendon organs
○ Bicep flexor muscle contracts
○ Tendon organ fires via 1b afferents
○ In spinal cord activates excitatory interneurons to tricep flexor muscles and inhibitory interneurons to biceps
○ Terminates activity in bicep
○ Ankle extensor
○ Activate inhibitory interneurons back to extensors
Reticulospinal
• General body orientation and simple motor patterns
• Inputs from motor cortex and cerebellum
• Mesencephalic locomotor region MLR
○ Shik et al, 1960s
§ Electrical stimulation of the midbrain elicited locomotion in cats
§ Low intensity = walking
§ Increased intensity = trotting, then galloping
○ MLR activates reticulospinal system to switch on movements
○ Signal to switch on CPG
§ MLR does not coordinate or organise movement
CPG interprets strength of stimulation to program appropriate output
Rubrospinal
- Controls reaching and limb movements in mammals
- Some direct inputs to motor neurons
- Inputs from motor cortex and cerebellum
- In humans - replaced by corticospinal tract, inputs to cerebellum
Corticospinal
• Most important in mammals • Large lateral pathway ○ Left ○ Crosses in the brainstem • Ventromedial pathway ○ Smaller ○ Does not cross • Inputs to motor neurons are widespread in humans
vestibulospinal
- Maintaining equilibrium
* Projections to limb extensor/antigravity muscles
divide in spinal cord
• Medial pathways ○ Cortico, vestibulo, reticulo, tectospinal ○ Proximal muscles • Lateral pathways ○ Cortico, rubrospinal ○ Extremeties/distal muscles
fast pathways - activation of CPG
mecenphalic region stimulated
reticulospinal tract
long loop reflexes
corticospinal tract
lesions: spacticity
delays need to be eradicated
long term modulatino
shape appropriate reflexes
infants and cerebral palsy - stretch reflex in both flexor and extensor
varying output of CPG by supraspinal systems
slow pathways
slow pathway function
change of motor output through functinoal reorganisation of the CPG through amines and peptides
decrease or increase output
large potential bcs many neuromodulators
eg amines increases during loom
cerebellum role
comparing intended and actual movement
motor control
motor learning/ predictive motor control
non-motor functions
planning and execution of movements bcs of timing and scaling
feedforward input from motor cortex so dont need for muscle contraction
vestibulocerebellum
head and axial movements
spinocerebellum
integrates sensory info about ongoing movements from sc + efferent copy
lateral cerebrocerebellum
planning and execution –> outputs via thalamus to basal ganglia
otholith organ
head position signal : direction and position
head position signal
utrice- horizontal
saccule - vertical
due to the directional sensitiivty of the hair cells
semicircular canals
reflects angle of head rotation