Most Common Part 1 Flashcards

Compiled most commons

1
Q

Most common cause of congenital UTO

A

UPJ obstruction

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2
Q

Most common nonobstructive cause of
dilatation of the urinary tract observed in
prenatal utz

A

VUR

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3
Q

Most common vascular lesion in LN:

A

simple

vascular immune deposition

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4
Q

Most common lesion in SLE active class 3 and 4

A

simple

vascular immune deposition

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5
Q

Most common class LN where you find
Noninflammatory necrotizing vasculopathy
in arterioles

A

active class IV LN

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6
Q
Most common class of LN where
tubulointerstitial immune deposits are found
A

active proliferative class III and IV LN.

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7
Q

Most common clinical manifestation of APL

A

DVT

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8
Q

Most common pattern of glomerular

involvement for MCTD

A

membranous

nephropathy

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9
Q

Most common form of crescentic GN

A

Pauciimmune

rapidly progressive GN

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10
Q

Most common ANCA for px with WG w

granulomatous lesions

A

C ANCA against

PR3

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11
Q

The most common associated illness found

in patients with classic PAN

A

hepatitis B

infection

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12
Q

Most common organ affected in PAN

A

kidney

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13
Q

Most common clinical findings of true PAN

A

constitutional symptoms of fever, weight

loss, and malaise

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14
Q

For Microscopic polyangitis: most typical

histologic finding

A

focal segmental
necrotizing GN with crescents affecting from
few to many glomeruli

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15
Q

Most common ANCA in Churg Strauss

Syndrome

A

Most are P-ANCA and anti-MPO positive

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16
Q

most common form of arteritis in Western

countries

A

Temporal arteritis

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17
Q

Most common Ig deposited (seen in IF) in

HSP

A

IgA

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18
Q

Most common Ig depostited in LN

A

IgG

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19
Q

Most common extrarenal findings in

Goodpastures

A

pulmonary

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20
Q

most common biopsy picture for

Goodpasture

A

diffuse crescentic GN
involving more than 50% of glomeruli, with
exuberant, predominantly circumferential
crescents

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21
Q

Most common IF finding Goodpasture

A

intense and diffuse linear staining for IgG

involving the GBM

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22
Q

Most common renal pathology in Sjogrens

A

tubulointerstitial nephritis

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23
Q

Most common renal findings in Sarcoidosis

A

granulomatous interstitial nephritis,
nephrolithiasis, and tubular functional
abnormalities

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24
Q

The most common organ involved in AL

amyloid

A

Kidneys, heart, peripheral nerves

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25
Q

Most common cause of death in amyloidosis

A

Cardiac involvement with associated heart

failure and arrhythmias

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26
Q

Most common renal presentation of

cryoglobulinemia

A

acute nephritic picture

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27
Q

Most common disease associated with

Mixed Cryo type II and III

A

HCV

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28
Q

Most pathognomonic ophthalmic abnormality

in Alport’s

A

Anterior lenticonus

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29
Q

Most common GN assocd with NSAIDS

A

MCD (with interstitial nephritis)

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30
Q

Most common GN assocd with Heroin

A

FSGS

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31
Q

Most common GN assocd with Gold

A

Membranous

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32
Q

Most common GN assocd with Pencillamine

A

Membranous

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33
Q

Mos common GN assocd with carcinoma:

A

Membranous

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34
Q

Most common GN associated with Hep B

A

Membranous

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35
Q

Most common risk factor for HIVAN

A

IV drug use

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36
Q

Most common glomerular lesions among

whites who have HIV (no IV drug use)

A

diffuse mesangial hyperplasia

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37
Q

Most common glomerular lesions among

BLACKS who have HIV (no IV drug use)

A

severe FSGS

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38
Q

Most common pattern of IMMUNE

COMPLEX mediated GN seen in HIV

A

MGPN

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39
Q

Most typical GN lesion in IE:

A

focal and
segmental endocapillary proliferative GN w
focal crescents

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40
Q

The most common pattern of Monoclonal Ig

Deposition disease

A

LCDD – light chain

depos. Dse

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41
Q

Most common cause of gross hematuria in

young females

A

UTI

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42
Q

Most common underlying systemic disease

causing nephrotic syndrome

A

DM

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43
Q

In lipiduria, the urine fat most commonly

comes from

A

derived HDL

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44
Q

Major lesion of DMN Type 1 leading to renal dsynfxn:

A

Mesangial expansion

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45
Q

Major cause of mortality among T1DM

A

ESRD

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46
Q

Major cause of fistula malfunctions in DM px

A

inadequate arterial inflow

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47
Q

Major nutritional problem of PD

A

gain of glucose

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48
Q

Most important host defense that maintains

sterility of urine

A

normal, unobstructed

voiding

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49
Q

Most abundant protein in urine

A

Tamm

Horsfall protein

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50
Q

Most common cytokines involved in UTI

A

IL-6

and IL-8

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51
Q

Most UTIs post KT occur

A

first 3 months

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52
Q

Most common pathogen UTI post KT

A

Enterobac – E. coli

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53
Q

Most common pathogen Emphysematous

cystitis/PN

A

E. coli, Kpn

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54
Q

Most common pathogen Xanthogran PN

A

P. mirabilis (followdb by Ecoli)

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55
Q

Most common urine picture in GUTB

A

sterile pyuria with hematuria

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56
Q

Most common CT finding for GUTB

A

renal calcification

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57
Q

Most common pathogen cystitis

A

E. coli

2nD:S. saprophyticus

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58
Q

Most impt behavioral assocn of UTI in

premenop women

A

sexual intercourse

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59
Q

Strongest assocn of recurrent acute cystitis

in postmenop women

A

History of prior UTI at

a younger age

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60
Q

The most common cause of community

acquired bacteremia

A

urinary tract

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61
Q

The most common pathogen causing

asymptomatic bacteriuria in men >65

A

CONS

62
Q

Most common and important parastitic

infestation of Urinary tract

A

Schistosoma

hematobium

63
Q

Most common extrarenal findings in

Atheroemboilic dse

A

Cutaneous symptom

64
Q

Most common internal organ affected by

Atheroembolic dse

A

kidney

65
Q

Most common intervention reported to incite

chole embolizaion

A

arteriographic procedures

coro angio

66
Q

Most common sickle cell variant to manifest

with gross hematuria

A

Hb-AS2

67
Q

Most common sickle cell variant to manifest

with proteinuria

A

homozygous Hb-SS

68
Q

Most common source of bleeding in papillary

necrosis in px with SC:

A

Left kidney

69
Q

Most prominent lesions seenin pathology of

px with sickle cell disease:

A

medullary lesions

70
Q

Most common cause of renal failure in sickle

cell diseae

A

FSGS

71
Q

Most common location of Renal artery

aneurysm

A

bifurcation of renal artery or in first order branch arteries

72
Q

Most common type of renal artery aneurysm

A

saccular type

73
Q

Most common surgical tx for treating renal

artery aneurysm

A

in situ aneurysmectomy

and revasularization

74
Q

Most common manifestation of chronic

dissection of renal artery aneurysm

A

Renovascualar HPN

75
Q

RVT in adults most commonly assocated

with

A

Nephrotic syndrome

76
Q

Most common cause of AKI

A

prerenal azotemia

77
Q

Most common precipitating event for type 1

HRS:

A

SBP

78
Q

Most common complication of AKI

A

infection

79
Q

Principal risk factor for devt of AKI

A

CKD

80
Q

Most common immunologic cause of

Intersitial nephritis

A

Acute allograft rejection

in transplant px

81
Q

Most common causes of intrinsic AKI

A

ischemic and septic ATN

82
Q

Second most common cause of intrinsic AKI

A

nephrotoxic

83
Q

Most nephrotoxic antibiotic

A

Neomycin

84
Q

Most common site of cisplatin nephrotoxicity

in rats

A

S3 segment of PT in corticomedullary

region

85
Q

Most common cause of postrenal azotemia

A

bladder neck obstruction

86
Q

Most common segment in PT damaged in

ischemic injury

A

S3

87
Q

Mot common segment involved in toxic

nephropathy

A

S1, S2

88
Q

Most common intrinsic AKI that presents with

FeNa of <1%:

A

radiocontrast, rhabdo

89
Q

Most common location of extra adrenal

tumor in pheo

A

Abdomen - superior and

inferior paraaortic areas

90
Q

Most common / α-blocker of choice for med

tx of pheo

A

phenoxybenzamine

91
Q

The most common routine laboratory finding

in GRA

A

low PRA level

92
Q

Highest level of NOS activity

A

medullary collecting ducts

93
Q
FiBromuscular dysplasia (cause of RAS)
assocd s string of beads appearance
A

Medial fibroplasia

94
Q

Renal reperfusion injury most pronounced in

A

prox tubules

95
Q

FMD more common in right renal artery

A

women

96
Q

Most common renovascular lesion

A

Atherosclerosis affecting renal arteries.

ARAS

97
Q

Most cmon presentation RAS

A

worsening of preexisting hpn

98
Q

Most common cause of DGF in deceased

donor kidney recipients

A

ischemic ATN

99
Q

Most common cause of allograft loss in the

first week

A

Acute vascular thrombosis

100
Q

Most common time period acute rejections

occur in:

A

first 6 mths

101
Q

Most common time period acute rejections

A

first 6 mths

102
Q

Most commonly implicated cause of AIN in

KT px:

A

TMP SMX

103
Q

Best test to demonstrate bladder leak:

A

cystography

104
Q

Most commn time frame that UTO occurs

post KT

A

early post KT period (within 6 mos)

105
Q

most important cause of allograft dysfunction

after the first 6 to 12 months

A
Chronic
allograft injury (CAI).
106
Q

Principal risk factors in persistent hyperpara

in post KT:

A

degree of pre transplant

hyperpara, duration of dialysis

107
Q

Principal cause of hyperK in post KT

A

CNI

108
Q

The most important cause of hyperuricemia

and gout after transplant

A

CNIs (particularly

CYA)

109
Q

Most commonly affected bone in

Osteonecrosis post KT

A

the femoral head

110
Q

Most sensitive diagnostic modality to dx

osteonecrosis

A

MRI

111
Q

Most of the bone loss in post KT

osteoporosis occurs in the

A

first 6 months

after transplant.

112
Q

Most common cause of early and late

allograft loss

A

Death with a functioning

allograft (mc. Casue: cardiovascular disease)

113
Q

Most common type of PTLD post transplant

A

non-Hodgkin’s lymphomas

114
Q

Most common time frame PTLD occurs post

KT:

A

24 months after transplant

115
Q

Major risk factor for pre

eclampsia

A

APAS (followed by Renal

disease)

116
Q

Most reliable sign of superimposed pre
eclampsia on chronic HPN (in the absence of
underlying renal disease

A

new onset
proteinuria (>300 mg/day) usually with
worsening HPN

117
Q

The most common cause of AKI during

pregnancy

A

prerenal azotemia due to
hyperemesis gravidarum or vomiting from
acute pyelonephritis

118
Q

Most common stones in pregnancy

A

Calcium

oxalate and calcium phosphate

119
Q

Most common renal problem encountered

during gestation

A

infection of urinary trac

120
Q

Most common complication of pregnancy in

KTR:

A

hypertension

121
Q

Most relevant phosphatonin in the setting of

CKD

A

FGF23

122
Q

Most important transport channel in the

transcellular uptake of Ca in the kidneys

A

TRPV5 (as opposed to intestines: TRPV 6)

123
Q

highest density of protein expression of CasR

A

cortical thick ascending

limb.

124
Q

most important determinantin minute to

minute PTH secretio

A

extracellular

concentration of ionized calcium

125
Q

Most potent phosphate-binding compounds

A

Aluminum

126
Q

most effective agent available for reducing

serum PTH levels in patients with ESRD

A

Cinacalcet

127
Q

The most frequent side effect of cinacalcet

A

nausea and vomiting

128
Q

Most common and most troublesome side

effect of icodectrin

A

Skin rashes

129
Q

most common pathway of invasion in

peritonitis

A

catheter’s lumen
(the next most frequent pathway is by the
periluminal route)

130
Q

Most common organism causing peritonitis

A

G (+) particularly S. epidermidis

131
Q

Most common overt complication of primary

Hyperpara

A

nephrolithiasis

132
Q

Most important inhibitor of stone formation

A

citrate

133
Q

Most important regulator of citrate reabsorption

A

cell pH in the proximal tubule

134
Q

The most prevalent cause of hyperuricosuria

in px with kidney stones

A

excessive dietary

purine

135
Q

Most important and invariant finding in uric

acid nephrolithiasis

A

low urinary pH

136
Q

Most common encountered stone with

HYPERURICOSURIA

A

ca oxalate

137
Q

Most important stimuli for AVP secretion

under physiologic conditions

A

osmotic

pressure of plasma

138
Q

Most common mutation in Congential NDI

A

mutations of the AVP V2 receptor

139
Q

most common cause of drug induced NDI

A

lithium

140
Q

Most common causes of

pseudohyponatremia

A

primary or secondary

hyperlipidemic disorders.

141
Q

Most common extrarenal cause of

hypovolemic hyponatremia:

A

gastrointestinal

disease with vomiting or diarrhea.

142
Q

Most common cause of diuretic induced

hyponatremia

A

thiazides

143
Q

Most common cause of hyponatremia in

hospitalized px:

A

SIADH

144
Q

Most common tumor causing SIADH

A

Small cell Ca

145
Q

Most common side effect of Conivaptan

A

injection site reactions

146
Q

Most commonly expressed KCC in the proximal tubule

A

KCC3 , KCC4

147
Q

Most AQP1 in the tDL is expressed in what

type of epithelial cell:

A

type II

148
Q

Most AQP1 expressed in this segment

A

thin descending limb of LOH (OM)

149
Q

NKCC2 protein with the highest affinity for

Cl

A

NKCC2B

150
Q

Most NaKATPase expressed in

A

DCT