More drug reactions Flashcards

1
Q

Cinchonism- tinnitus, hearing/vision loss, psychosis, and cognitive impairment

A

Quinidine, quinine

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2
Q

Parkinson-like syndrome

A

MR. Parkinson
Metoclopramide
Reserpine
antiPsychotics

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3
Q

Seizures

A
"I BITE my tongue"
Isoniazid
Buproprion
Imipenem/cilastatin
Tramadol
Enflurane
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4
Q

Tardive Dyskinesia

A

Metoclopramide, Antipsychotics

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5
Q

FANCONI syndrome

A
"CITE"
Cisplatin
Ifosfamide
Tenofovir
Expired tetracyclines
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6
Q

Hemorrhagic cystitis

A

cyclophosphamide, ifosfamide

PREVENT with mesna

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7
Q

Interstitial nephritis

A
"FuN PIPS"
Furosemide
NSAIDs
Proton Pump Inhibitors
Penicillin
Sulfa drugs
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8
Q

Dry cough

A

Ace inhibitors

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9
Q

Pulmonary fibrosis

A
"My Nose Cannot Breathe Bad Air"
Methotrexate
Nitrofurantoin
Carmustine
Bleomycin
Busulfan
Amiodarone
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10
Q

Antimuscarinic effects (4)

A

Atropine, TCAs, H1-blockers, antipsychotics

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11
Q

Disulfiram-like reactions (5)

A

“Sorry Pals, Can’t Go Mingle”

1st gen sulfonylureas, procarbazine, cephalosporines, griseofulvin, metronidazole

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12
Q

Nephrotoxicity/ototoxicity

A

Aminoglycosides, vancomycin, loop diuretics, cisplatin, amphotericin B

Cisplatin may respond to amifostine

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13
Q

CYP 450 Inducers

A
"Chronic alcoholics STeal Phen Phens and Never Reject Greasy Carbs"
Chronic alcohol
St. John's Wort
Phenytoin
Phenobarbital
NEVIRAPINE (antiviral)
Rifampin
Griseofulvin
Carbamazepine
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14
Q

CYP 450 Substrates

A
"AT COWs"
Anti-epileptics
Theophyline
Cyclophosphamide
OCPs
Warfarin
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15
Q

CYP 450 Inhibitors

A
"SICKFACES.COM GQR"
Sodium valproate
Isoniazid
Chloramphenicol
Ketoconazole
Fluconazole
Acute Alcohol
Cimetidine
Erythromycin
Sulfonamides
Ciprofloxacin
Omeprazole
Metronidazole

Grape fruit juice
Quinidine
Ritonavir

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16
Q

Sulfa Drugs

A
"Scary Sulfa Pharm FACTS"
Sulfonamide antibiotics
Sulfasalazine
Probenecid
Furosemide
Acetazolamide
Celecoxib
Thiazide
Sulfonylureas