Cancer Memorizing

Question 1

Paraneo: Acanthosis nigricans

Answer 1

GASTRIC ADENOCA
other visceral malignancies
… more commonly insulin resistance

Question 2

Paraneo: PTHrP–> Hypercalcemia

Answer 2

Squamous cell carcinoma: lung, head/neck

Renal, bladder, breast, ovarian Ca

Question 3

Paraneo: Calcitriol –> Hypercalcemia

Answer 3

Lymphoma

Question 4

Paraneo: EPO–> Polycythemia

Answer 4

RCC, HCC, hemangioblastoma, pheochromocytoma, leiomyoma

Question 5

Thymomas (cause 3 paraneoplastic syndromes)

Answer 5

1) Pure red cell aplasia (anemia with low retic)
2) Good syndrome = hypogammaglobulinemia
3) Myasthenia gravis

Question 6

Pancreatic adenocarcinomas (cause 2)

Answer 6

1) Trousseau syndrome = migratory superficial thrombophlebitis
2) Nonbacterial thrombotic (marantic) endocarditis

Question 7

Paraneo: Anti-NMDA receptor –> encephalitis –> psychiatric disturbance and autonomic instability

Answer 7

OVARIAN TERATOMA WHHHAAAT

Question 8

Paraneo: “Dancing eyes, dancing feet” = opsoclonus-myoclonus ataxia

Answer 8

Neuroblastoma (children), small cell (adults)

Question 9

Paraneo: Abs against Purkinje cells –> paraneoplastic cerebellar degeneration

Answer 9

Anti-Hu: small cell
Anti-Yo: Gyn and breast
Anti-Tri: Hodgkin

Question 10

Paraneo: Abs against Hu in neurons –> encephalomyelitis

Answer 10

Small cell