More CP

Question 1

composition of RBC basophilic stippling

Answer 1

aggregated ribosomes

Question 2

composition of howell-jolly bodies

Answer 2

DNA

Question 3

composition of pappenheimer bodies

Answer 3

Iron

Question 4

composition of Heinz bodies

Answer 4

denatured Hgb

Question 5

Can you see Heinz bodies on Wright-Giemsa stain?

Answer 5

No. Need supravital stain

Question 6

composition of cabot rings

Answer 6

remnant of mitotic spindle

Question 7

Which HLA allele is associated with grave’s disease

Answer 7

HLA-DR3

Question 8

What type of virus is rotavirus

Answer 8

double stranded, non-encapsulated RNA

Question 9

What is the MOA of fluoroquinolones

Answer 9

inhibit DNA topoisomerase

Question 10

What two bacteria are CAMP test positive

Answer 10

• Group B strep (Strep agalaticae)

- Listeria

Question 11

What coagulation factor deficiencies are inherited in an X-linked recessive manner

Answer 11

Hemophilia A and B (factors 8 and 9)

Question 12

What coagulation factor deficiencies are inherited in an autosomal recessive manner

Answer 12

Factors 7 and 11

Question 13

What coagulation factor deficiencies are inherited in an autosomal dominant manner

Answer 13

von willebrand disease

Question 14

Which BRCA mutation is higher risk for male breast ca

Answer 14

BRCA2

Question 15

Pt with anti-Kell. What percentage of white donor population will have antigen-neg blood

Answer 15

90%

Question 16

Patient with hyperthermia, dry skin, flushing, AMS, psychosis

Answer 16

anticholinergic poisoning

-Atropine, antihistamines, TCAs, scopolamine

Question 17

patient with salivation, lacrimation, urination, diarrhea, GI cramps, emesis, diaphoresis, miosis, wheezing

Answer 17

Cholinergic poisoning

organophosphates, pilocarpine, carbamate

Question 18

patient with hypertension, tachycardia, mydriasis, anxiety, hyperthermia

Answer 18

adrenergic poisoning

-amphetamines, cocaine, pseudoephedrine, PCP

Question 19

poisoning with what two agents gives you abnormally high venous oxygen content

Answer 19

cyanide

hydrogen sulfide

Question 20

poisoning with which alcohol will give you oxlate crystals in urine

Answer 20

ethylene glycol

Question 21

What is toxic metabolite of acetominophen

Answer 21

N-acetyl-P-benzoquinone imine

NAPQI

Question 22

What is inheritance pattern and defect in familial hypercholesterolemia

Answer 22

Autosomal dominant

Deficiency or malfunctioning of LDL receptors

Question 23

What tumors show increased AFP

Answer 23

yolk sac

HCC

Question 24

What metabolites can be found to be elevated in the urine of pts with neuroblastoma

Answer 24

Vanillylmandelic acid (VMA, derived from epi and norepi)
Homovanillic acid (HVA, derived from dopamine)

Question 25

Which ketone is urine dipstick test sensitive to

Answer 25

acetoacetic acid

Question 26

What is normal pH of urine

Answer 26

mildly acidic pH 6.0

Question 27

What are light criteria for transudate vs exudate

Answer 27

Exudate: Pleural fluid: serum protein ratio >0.5 Pleural fluid:serum LD ratio >0.6 Pleural fluid LD > 2/3 ULN serum LD

Question 28

allergic rhinitis, severe asthma, fever, hypereosinophilia

Answer 28

eosinophilic granulomatosis with polyangiitis

Question 29

By CLIAA standards, how frequently must QC be performed

Answer 29

once every 24 hours or as recommended by manufacturer