More CP Flashcards
composition of RBC basophilic stippling
aggregated ribosomes
composition of howell-jolly bodies
DNA
composition of pappenheimer bodies
Iron
composition of Heinz bodies
denatured Hgb
Can you see Heinz bodies on Wright-Giemsa stain?
No. Need supravital stain
composition of cabot rings
remnant of mitotic spindle
Which HLA allele is associated with grave’s disease
HLA-DR3
What type of virus is rotavirus
double stranded, non-encapsulated RNA
What is the MOA of fluoroquinolones
inhibit DNA topoisomerase
What two bacteria are CAMP test positive
- Group B strep (Strep agalaticae)
- Listeria
What coagulation factor deficiencies are inherited in an X-linked recessive manner
Hemophilia A and B (factors 8 and 9)
What coagulation factor deficiencies are inherited in an autosomal recessive manner
Factors 7 and 11
What coagulation factor deficiencies are inherited in an autosomal dominant manner
von willebrand disease
Which BRCA mutation is higher risk for male breast ca
BRCA2
Pt with anti-Kell. What percentage of white donor population will have antigen-neg blood
90%
Patient with hyperthermia, dry skin, flushing, AMS, psychosis
anticholinergic poisoning
-Atropine, antihistamines, TCAs, scopolamine
patient with salivation, lacrimation, urination, diarrhea, GI cramps, emesis, diaphoresis, miosis, wheezing
Cholinergic poisoning
organophosphates, pilocarpine, carbamate
patient with hypertension, tachycardia, mydriasis, anxiety, hyperthermia
adrenergic poisoning
-amphetamines, cocaine, pseudoephedrine, PCP
poisoning with what two agents gives you abnormally high venous oxygen content
cyanide
hydrogen sulfide
poisoning with which alcohol will give you oxlate crystals in urine
ethylene glycol
What is toxic metabolite of acetominophen
N-acetyl-P-benzoquinone imine
NAPQI
What is inheritance pattern and defect in familial hypercholesterolemia
Autosomal dominant
Deficiency or malfunctioning of LDL receptors
What tumors show increased AFP
yolk sac
HCC
What metabolites can be found to be elevated in the urine of pts with neuroblastoma
Vanillylmandelic acid (VMA, derived from epi and norepi) Homovanillic acid (HVA, derived from dopamine)
Which ketone is urine dipstick test sensitive to
acetoacetic acid
What is normal pH of urine
mildly acidic pH 6.0
What are light criteria for transudate vs exudate
Exudate:
Pleural fluid: serum protein ratio >0.5
Pleural fluid:serum LD ratio >0.6
Pleural fluid LD > 2/3 ULN serum LD
allergic rhinitis, severe asthma, fever, hypereosinophilia
eosinophilic granulomatosis with polyangiitis
By CLIAA standards, how frequently must QC be performed
once every 24 hours or as recommended by manufacturer
