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Residency Boards > Misc AP > Flashcards

Misc AP Flashcards

1
Q

Minimum # of squamous cells for adequate PAP

A

Liquid based 5,000

Conventional 8,000-12,000

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2
Q

Meigs syndrome

A

Triad of ascites, pleural effusion and benign ovarian fibroma

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3
Q

most common malignancy associated with urethral diverticulum?

A

bladder adenocarcinoma

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4
Q

Subepidermal blisters with predominantly eosinophils

A

Bullous Pemphigoid

Gestational pemphigoid

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5
Q

Subepidermal blisters with predominantly neutrophils

A

Dermatitis Herpetiformis

Linear IgA disease

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6
Q

Subepidermal blisters with little or no inflammation

A

Porphyria Cutanea Tarda

Pseudoporhyria

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7
Q

Tense bullae, subepidermal cleft w/ eos, Linear C3 and IgG at DEJ

A

Bullous Pemphigoid

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8
Q

skin showing confluent parakeratosis, regular acanthosis with suprapapillary thinning and absence of granular layer

A

psoriasis

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9
Q

papules on flexor surfaces, elbows and wrists

band-like lymphocytic infiltrate obscuring DEJ, hyperkeratosis, hypergranulosis, irregular acanthosis and colloid bodies

A

Lichen planus

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10
Q

what conditions result in Serous atrophy of bone marrow?

A

AIDS, extreme malnutrition/starvation

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11
Q

painful superficial tumors

A

ANGEL

Angiolipoma, neuroma, glomus tumor, eccrine spiradenoma, leiomyoma

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12
Q

What antibody is present in pemphigus vulgaris?

A

anti-desmoglein 3 (mucosal)

anti-desmoglein 1 (cutaneous)

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13
Q

Mutations in what gene are found uveal melanoma and blue nevi

A

GNAQ and GNA11

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14
Q

What precursor is associated with basaloid and warty vulvar carcinomas?

A

VIN

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15
Q

Liver disease with pos ANA or anti-SMA

A

Type 1 AIH

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16
Q

Liver disease with pos anti-LKM1

A

AIH type 2

17
Q

Liver disease with anti SLA

A

AIH type 3

18
Q

Liver disease with antimitochondrial antibodies

A

PBC

19
Q

Liver disease with p-ANCA

A

PSC

20
Q

What condition is associated with bike ductular cholestasis (inspissated bile concretions within proliferated periportal bile ductular structures)

A

Sepsis

21
Q

Causes of microvesicular steatosis

A

Drugs (anti-retrovirals, tetracycline toxicity, valproic acid)
acute fatty liver of pregnancy
Reye syndrome

22
Q

5 things that cause granulomas in liver

A 
1-sarcoidosis
2-TB
3-PBC
4-drug hepatotoxicity
5-schistosomiasis
23
Q

Minimum cellularity anal pap

A

2000-3000 nucleated squamous cells

24
Q

What renal neoplasm shows loss of chr1 and Y

A

Onco and chromo

25
Q

What renal neoplasm shows trisomy 7 and 17?

A

Papillary RCC

26
Q

Two variants of germ cell tumor that occur in testes of prepubertal boys

A

Yolk sac

Teratoma

27
Q

What is tested for in urovysion FISH?

A

aneuploidy for chromosomes 3, 7, 17, and loss of the 9p2

28
Q

What is Ca 19-9 a marker of?

A

Pancreas ca

29
Q

Papillary RCC GENETICS

A

Loss of Y

Gains of chr7&17

30
Q

What mutation is found in pilocytic astrocytoma?

A

BRAF

31
Q

What genetic abnormality is seen in meningioma?

A

Monopoly chr22

NF2 gene on chr22

32
Q

Carney complex

A

LAMB syndrome
Lentigines, atrial myxoma, myxoid neurofibroma
Mutation in PRKAR1A on chr 17

33
Q

Carney triad

A

gastric GIST
Pulmonary chondroma
Extra-adrenal paragangliomA

34
Q

What 2 molecules are implicated in systemic castelman disease?

A

IL-6 and VEGF

35
Q

Translocation in ewing sarcoma

A

t(11;22) EWSR1-FLI1

36
Q

What is most accurate evidence for death due to anaphylaxis

A

serum beta tryptase

37
Q

follicular cervicitis is associated with what?

A

Chlamydia trachomatis

38
Q

Which germ cell tumor shows increased AFP?

A

Yolk sac

39
Q

What tumor has schiller-duvall bodies

A

yolk sac

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