Mood Disorders

Question 1

Difference between emotion and mood?

Answer 1

Mood is sustained (days, weeks, or longer)

Question 2

2 “low” mood disorders?

Answer 2

major depressive disorder

persistent depressive disorder

Question 3

3 “low/high” mood disorders?

Answer 3

bipolar I
bipolar II
cyclothymia

Question 4

Lifetime prevalence and annual incidence of major depressive disorder?

Answer 4

12-17%

1.6%

Question 5

MDD criteria?

Answer 5

low mood or anhedonia
\+ 4 of following:
Sleep disturbance
Interest reduction
Guilt
Energy loss
Concentration impairment
Appetite changes
Psychomotor change
Suicidal thoughts

Question 6

Predisposing factors for MDD?

Answer 6

serotonin receptor polymorphisms
childhood illness
unemployment
loss of parent before age 11
social isolation
childhood abuse

Question 7

Duration of MDD episode (treated and non)

Answer 7

9 months

3 months

Question 8

MDD recurrence?

Answer 8

50% after 1st episode
85% lifetime recurrence
consider lifetime meds after 3 episodes

Question 9

Sleep changes in depression?

Answer 9

less stage 3-4 sleep
shortened REM latency (get there quicker)
increased REM duration

Question 10

Best predictor of attempting suicide?

Answer 10

past attempt

Question 11

Prevalence of substance-induced mood disorder?

Answer 11

0.3%

Question 12

Mania criteria?

Answer 12

Distractible
Impulsive behavior
Grandiosity
Flight of ideas
Activity increase
Sleep decrease
Talkativeness

Question 13

Bipolar I criteria?

Answer 13

manic episode not explained by meds or other condition.

Question 14

Bipolar II disorder criteria?

Answer 14

major depressive episode and hypomania

Question 15

What is hypomania?

Answer 15

4 days of elevated, expansive, irritable mood
and
abnormal increased activity or energy

Question 16

Suicide risk in bipolar?

Answer 16

15x higher than gen pop

Question 17

Persistent Depressive Disorder criteria?

Answer 17

depressive symptoms on most days for at least 2 years

Question 18

Double depression criteria?

Answer 18

acute MDD episode overlying persistent depressive disorder

Question 19

Cyclothymia criteria?

Answer 19

periods of hypomania and depressive symptoms for 2 years

Question 20

Bipolar-NOS criteria?

Answer 20

very rapid alteration between manic and depressive symptoms that do not meet time thresholds for bipolar diagnosis

Question 21

What is seasonal affective disorder?

Answer 21

depressive symptoms, sometimes with hypomania, that correlates with seasons (winter - spring)

Question 22

Atypical depression differences from MDD?

Answer 22

mood reactivity (periods of improved mood)
hypersomnia, hyperphagia
leaden paralysis
interpersonal rejection sensitivity

Question 23

Atypical depression tx?

Answer 23

SSRI and CBT

MAOI is 2nd line

Question 24

Postpartum depression criteria?

Answer 24

MDD symptoms within one month of delivery (before or after)