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Psychological Disorders > Monoamine theory of anxiety > Flashcards

Monoamine theory of anxiety Flashcards

1
Q

Mendelowicz + Stein (2000)

A

maladaptive when inappropriate/ impairs normal functioning

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2
Q

Historical approach

A

alcohol+ opium= sedation

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3
Q

1903

A

barbituates

addiction/ withdrawal/ lethal interactions/ tolerance

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4
Q

1960s

A

BDZ introduced

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5
Q

1970s

A

BDZ mechanism discovered

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6
Q

Ballenger (1999)

A

drugs that increase 5-HT+ NA and decrease GABA cause anxiety

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7
Q

Mohler (2012)

A

BDZ increase GABA therefore reduce anxiety symptoms

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8
Q

Baldwin (2014)

A

buspirone improves GAD symptoms and lowers 5-HT
BDZ only work for GAD
ADs work for PD but by increasing 5-HT

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9
Q

Baldwin (2015)

A

pregabalin works for GAD (via Cl- channels instead)

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10
Q

Rickels (1993)

A

TCAs= just as effective in GAD (reduces distinction)

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Psychological Disorders (7 decks)

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