Molecular Genetics Flashcards

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1
Q

a modified form of guanine nucleotide added onto the end of a pre-mRNA molecule

A

5’ cap

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2
Q

a nucleotide triplet that is on one end of a tRNA molecule that base pairs with a particular complimentary codon on a mRNA

A

anticodon

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3
Q

a virus that infects bacteria, a phage

A

bacteriophage

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4
Q

linking enzyme in DNA replication, catalyzes the covalent bonding of the 3’ end of one fragment and 5’ end of another

A

DNA ligase

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5
Q

enzyme that catalyzes the elongation of DNA by adding new nucleotides to the 3’ end of an existing chain

A

DNA Polymerase

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6
Q

sequence in the primary transcript that remains in the RNA after RNA processing; region of DNA from which this sequence was transcribed

A

exon

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7
Q

an enzyme that untwists DNA at the replication fork, making two strands that are available to be template strands.

A

helicase

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8
Q

a small protein with a high proportion of positively charged amino acids that binds to the negatively charged DNA and plays a key role in chromatin structure.

A

histones

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9
Q

noncoding, intervening sequence, within a primary transcript that is removed during RNA processing

A

intron

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10
Q

discontinuously synthesized DNA strand that elongates by means of Okazaki fragments, each synthesized in a 5’ –> 3” direction away from the replication fork.

A

lagging strand

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11
Q

new complimentary DNA strand that is synthesized continuously along the template strand towards the replication fork in the mandatory 5’ —> 3’ direction.

A

leading strand

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12
Q

an enzyme that cuts DNA or RNA, either removing one or a few DNA or RNA bases or completely hydrolyzing the DNA or RNA into its component nucleotides

A

nuclease

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13
Q

a short segment of DNA synthesized away from the replication fork on a template strand during DNA replication, these segments are joined to make the lagging strand

A

okizaki fragments

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14
Q

site where the replication of a DNA molecule begins, consisting of a specific sequence of nucleotides.

A

origins of replication

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15
Q

organism that has a prokaryotic cell, an organism that has the domain Bacteria or domain Archaea

A

prokaryote

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16
Q

specific nucleotide sequence in the DNA of a gene that binds RNA polymerase, positioning it to start transcribing RNA at the appropriate place.

A

promoter

17
Q

modification of RNA primary transcripts, includes the joining together of exons, splicing out of introns, and altering the 5’ and 3’ ends.

A

RNA processing

18
Q

type of DNA replication in which the replicated double helix consists of one parental strand and one newly made strand

A

semiconservative model

19
Q

a DNA sequence in eukaryotic promoters critical in the transcription initiation complex

A

TATA Box

20
Q

enzyme responsible for the maintenance of the length of telomeres by adding guanine-rich sequences

A

telomerase

21
Q

the synthesis of RNA using a DNA template

A

transcription

22
Q

a change in genotype and phenotype due to the assimilation of external DNA by a cell

A

transformation

23
Q

synthesis of a polypeptide using the genetic information encoded in a mRNA molecule

A

translation