Module 8 Lec 9 Flashcards
What can karyotype banding patterns reveal?
Banding patterns can reveal chromosomal differences between species and causes of genetic diseases, including larger deletions.
How are karyotypes useful in studying genetic diseases
Karyotypes help identify chromosomal abnormalities, such as large deletions, which can cause genetic diseases.
What does a karyotype analysis involve?
Karyotype analysis involves studying the banding patterns on chromosomes to detect differences or abnormalities.
What do the bands in a karyotype represent?
The bands in a karyotype give the “address codes” for genes, helping to locate their positions on chromosomes.
What are the functions of centromeres?
Hold sister chromatids together (with cohesin).
Facilitate kinetochore formation for chromosome movement.
What is satellite DNA and where is it found?
Satellite DNA consists of repetitive, non-coding sequences (up to 300 bases long) found in centromeres, repeated thousands or millions of times.
What is satellite DNA?
Satellite DNA consists of repeat units (up to 300 bases in length) that are repeated thousands or millions of times.
What are centromeres and where are they located on chromosomes?
Centromeres are constrictions on chromosomes that contain blocks of repetitive, non-coding sequences called satellite DNA.
What are centromeres and what do they contain?
Centromeres are constrictions on chromosomes and contain blocks of repetitive, non-coding satellite DNA.
What is satellite DNA?
Satellite DNA consists of repeat units (up to 300 bases long) that are repeated thousands or millions of times.
What are the two main functions of centromeres?
Hold sister chromatids together (with cohesin).
Form a kinetochore (DNA-protein structure) for chromosome movement.
