MODULE 6 : DIVERSITY OF ENDOCRINE SYSTEM Flashcards
Acts locally. On neighborhood cells
PARACRINE
Distributed in the blood. Acts on distant target cells
ENDOCRINE
Acts on the same cell
AUTOCRINE
Produced by neurons but functions as hormones
NEUROHORMONE
Influences postsynaptic cells or effector cells
NEUROTRANSMITTER
Type of receptors which has second messengers that alters the activity of other molecules within the cell
CELL SURFACE RECEPTORS
Type of receptors which alter transcriptional activity of responsive genes
INTRACELLULAR RECEPTORS
A type of intracellular receptor which functions to activate and stimulate transcription
AMINO TERMINUS
A type of intracellular receptor which binds to a specific sequence of DNA
DNA BINDING DOMAIN
Type of intracellular receptor which binds to hormones
CARBOXY TERMINUS / LIGAND-BINDING DOMAIN
Hormone synthesized from cholesterol
ADRENAL STEROID HORMONE
Hormone derived from tyrosine
CATECHOLAMINE
Peptide hormones found in the heart
ATRIAL NATRIURETIC PEPTIDE / ANF
Hormones found in the pancreas
INSULIN
SOMATOSTATIN
Peptide Hormones found in the gastrointestinal tract
CKK
GASTRIN
Peptide hormone found in fat stores
LEPTIN
Amino acid hormones derived from tyrosine
THYROID HORMONES
CATECHOLAMINES
Amino acid hormones derived from tryptophan
SEROTONIN
MELATONIN
Amino acid hormones derived from glutamic acid
HISTAMINE
Inhibit release of growth hormone and thyroid stimulating factor
SOMATOSTATIN
Most commonly used as antacid and treatment for Calcium deficiency
CALCIUM LACTATE
Enhances mineral absoprtion
CASEIN PHOSPHOPEPTIDE
Involved in stress response
CORTICOTROPIN RELEASING HORMONE
Determines duration of pregnancy
CORTICOTROPIN RELEASING HORMONE
Releases follicle stimulation hormone and leutenizing hormone
GNRH-1
Effect of exercise in growth hormone synthesis
STIMULATES
Effect of hypoglycemia in growth hormone synthesis
STIMULATES
Effect of dietary carbohydrate in growth hormone synthesis
INHIBITS
Effect of glucocorticoids to growth hormone synthesis
INHIBITS
Results when there is a lack in the ability to synthesize or secrete growth hormones
GH-DEFICIENT DWARF
Lacks IGF-1, deficiency is post receptor in nature
PYGMIES
Low activity of GH receptors and low levels of circulating IGF-1 which results to an x’ss plasma GH
LARON DWARFS
X’ss amount of GH before epiphyseal closure
GIGANTISM
X’ss GH after epiphyseal closure; results in an acral bone growth
ACROMEGALY
Stimulates milk production
PROLACTIN
Stops the ejection of milk during pregnancy
HIGH LEVELS OF PROGESTERONE
A glycoprotein hormone responsible formgametogenesis and steroidgenesis
GONADOTROPINS
A glycoprotein hormones which is observed in high levels during menopause
FOLLICLE STIMULATING HORMONE
Response to the release of corticotropin releasing hormone in hypothalamus
ACTH
Results in an x’ss of ACTH
CUSHING’S SYNDROME
Causes lipolysis and fatty acid mobilization
LIPOTROPIN
Involved in pain perception, appetite and immune response
ENDORPHINS
Stimulates darkening if the skin
MELANOCYTE STIMULATING HORMONE
Carrier protein for T3 and T4
THYROXIN-BINDING GLOBULIN
Biologically active fraction of calcium
IONIZED CALCIUM
Effect of PTH in bone and kidney
BONE : INCREASE osteoclast activity
KIDNEY : REDUCE renal Calcium clearance by stimulation reabsorption
Responsible for attaching osteoclast to bone
CALCITONIN
Effect of calcitonin on intestines, bones and kidney
INTESTINES : REDUCES calcium reabsorption
BONES : REDUCES osteoclast activity
KIDNEY : REDUCED calcium and phosphate reabsorption
A chemical non-nutrient that serves as intercellular messenger
Hormone
Substances that allows communication between the Nervous system and adjacent tissues
Neurotransmitter