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Integrative Neuroimmunology > Module 6 > Flashcards

Module 6 Flashcards

1
Q

Is Vitamin D a vitamin or a hormone

A

Hormone

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2
Q

Give three reasons why Vitamin D is a hormone, not a vitamin

A

a. Is synthesized by the body
b. Is not required to be obtained through the diet
c

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3
Q

How much sunlight is required for 3 months supply of vitamin D

A

15 minutes fully exposed upper body

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4
Q

Name three things that impair Vitamin D metabolism

A

SNPs, infection, toxicity

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5
Q

What infection has the largest effect on the VDR

A

HIV

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6
Q

What infection has the second strongest effect on the VDR

A

Borellia

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7
Q

What does Vitamin D do in terms of the immune system

A

Downregulates the specific whilst upregulating the non-specific

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8
Q

How do AMPs work

A

a. Create pores in the pathogens membrane

b. Bind to essential molecules in the pathogen

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9
Q

Name 5 viruses that effect the VDR

A

HIV,Hep C, CMV,EBV, HSV6

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10
Q

How does H.Pylori effect the VDR

A

Produces capnine that binds to and inactivates the VDR

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11
Q

How do VDR viruses inhibit PTH

A

Long term production IFN alpha inhibits parathyroid function

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12
Q

What is the primary difference between l-form and mycoplasma

A

Mycoplasma never had a cell wall

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13
Q

Where do most mycoplasma infections normally reside

A

Respiratory and urogenital systems

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14
Q

What is mycoplasma pneumonia also known as?

A

Walking pneumonia, atypical and community acquired pneumonia

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15
Q

Where are calcidiol and calcitriol synthesized

A

Liver and kidney

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16
Q

What type of immune dysfunction do fungi produce

A

TH3

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17
Q

What is trachoma and what causes it?

A

Blindness caused by chlamydia infection in the eyelid

18
Q

List in order the biggest to smaller body types

A

GR,RB, BR, GB, RB, BG

19
Q

. Describe the hand shapes of each colour

A

a. Red is square and squat
b. Green is in proportion
c. Blues are longer and slender

20
Q

What is the extroverted colour and introverted colour

A

Red and blue

21
Q

Which hemisphere is most profoundly affected by VDR dysfunction?

A

Right

22
Q

Imbalance between which 4 primary oral bacteria set up a pathogenic state that leads to
cavities and gum disease?

A

Streptococcus Mutans/Sorbinus and Streptococcus Gordonii/Sanguinis

23
Q

Bacteria in the oral biome are primarily found in what form?

A

Biofilms

24
Q

. What value is a Healthy oral pH?

A

7.2

25
Q

What substance is produced by non-pathogenic streptococcus to protect them against
infectious strains?

A

H2O2

26
Q

Which conditions are associated with dysfunction in the following:

A

a. NADPH Oxidase – Granulomas
b. SOD – ALS, Neurodegenration
c. Myleoperoxidase – Cavities/Periodontal disease
d. Phenton reaction – Poor infection control by phagocytosis

27
Q

What is the primary effect of pathogen oral bacteria systemically?

A

Reduced detoxification

28
Q

What is a major risk of providing a chelator to patient?

A

a. Release pathogens from biofilms breakdown

b. Activate auto immune process if antibodies exist to metals

29
Q

Pain from SIj fixation, neck extensor inhibition and vastas medialis inhibition can be
alleviated by reducing inflammation in what nerve? How can this temporarily be achieved?

A

a. Deep peroneal nerve

b. Toe separator, walking barefoot

30
Q

What affect does aflatoxin have on glutathione and metallothionein levels?

A

Depletes them

31
Q

Which mycotoxin is closely associated with consumption of over ripened fruit and is
potentially immunosuppressive?

A

Patulin

32
Q

List 3 ways Borrelia can be transmitted

A

a. Tick bites
b. Sexually
c. Animal urine
d. Biting insects
e. Transplacental

33
Q

Does a Borrelia infection mean the patient has Lymes disease?

A

No

34
Q

How can glucosamine supplements greatly affect the patient with Borreliosis?

A

Stimulate growth through feeding

35
Q

Which aspects of immune function are altered by Borrelia infection?

A

. All. 1,25D changes alter HPA Axis function, direct effect on Th2, 3, 17, 22 aspects,
inhibition of VDR

36
Q

Why can a person with Borreliosis suffer with systemic allodynia?

A

Upregulation of markers in glial cells leading to central sensitization

37
Q

How does Burgdorferri differ from other strains of Borrelia in relation to hemispheric tone?

A

Drives Th1 response which up-regulates the left hemisphere

38
Q

When clearing an oral biofilm what should be given to a patient?

A

Liver support, Chelator, Anti-pathogen agent, toe separator if needed

39
Q

How can one differentiate if VDR viruses, Cell wall deficient bacteria or fungi should be
treated

A

Thymus thump, Levator scap or Trapezius weakness

40
Q

Photosensitivity in the left and right eye during borreliosis infection seems to be associated
with which co-infection?

A

a. Left – Campylobacter

b. Right - Rickettsia

Integrative Neuroimmunology (8 decks)

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