Module 1 Flashcards
A patient presents with poor short term memory loss, bumps into structures and gets lost easily.
Which area of the brain would most likely be the culprit?
Hippocampus
Abnormalities in diurnal cortisol rhythm combined with a lack of smell and short term memory
problems can be key warning signs for which neurodegenerative disease?
Alzheimer ’s disease
Which neurological structure plays a primary role in turning off the HPA Axis?
Hippocampus
Fear, anxiety and Post Traumatic Stress Disorder are associated with dysfunction of which
neurological structure?
Amygdala
Noradrenalin is used to improve focus by stimulating which structure?
Pre-Frontal Cortex
Diurnal cortisol rhythm is regulated by which two neurological structures?
Pineal gland and Hippocampus
The pineal, and hence melatonin, are greatly influenced by which aspect of the colour spectrum?
Blue light
What is the primary influence on Aldosterone production?
Sodium potassium ratio
Which hormone signals the pituitary to release ACTH?
CRH
Which hormone signals Zone 1 and 2 of the adrenal cortex to produce cortisol?
ACTH
Adaptogens have their affect on which structure in the HPA Axis feedback loop?
Primarily the hippocampus
Cortisol stimulation of the hippocampus elevates which neurotransmitter?
Glutamate
The Locus Coeruleus is the primary source of production for which neurotransmitter?
Noradrenalin
Aerobic exercise can rehabilitate the hippocampus through the elevation of which hormone?
BDNF, IGF-1, VEGF, FGF-2
Blockage of the Vitamin D Receptor has what affect on the HPA Axis?
Elevates Cortisol
List 5 conditions that are red flags for HPA Axis dysfunction…..
Anxiety, Depression, Autoimmune disease, Alzheimer’s disease, diabetes
List 5 factors that make a patient high risk for HPA Axis problems
Athletic body type, blonde hair, curly hair, fair, thin arms/legs with round stomach, Athlete, new mum
The HPA Axis dysfunctional patient will tend to feel how after activity?
Sleepy
The sympathetic dominant patient will tend to have what happen to their heart rate on activity?
Rapid elevation
Vague pain that exists in the upper QL/12th rib region is often due to dysfunction of which
structure?
Rogoff’s – Adrenal dysfunction
A negative SMP means there is no dysfunction of the Adrenal glands? (True/False)
False, this is a viscerosomatic reflex only. The test is sensitive, but not specific!
Pupils that are slow to constrict on direct light reflex are associated with dysfunction of which
structure?
Adrenal Dysfunction
Give 3 situations that can result in anisocoria
Hemispheric imbalance, Horners syndrome, glaucoma
Why is saliva the preferred method of assessment for adrenal Cortisol function?
Non-bound hormone, stable at room temperature, performed at home at regular stress level