Module 3 Flashcards
Why is the hippocampus so unique with regards to brain rehabilitation?
Believed to have neural stem cell proliferation throughout life
Which 2 herbs have a profound effect on Hippocampal health?
a. Cordyceps
b. Rhodiola
What can be done to rehabilitate the hippocampus?
a. Spatial awareness, memory and navigation exercises
b. Aerobic exercise
c. Reduce cortisol damage
d. Provide support
What type of fat is best to use in cooking?
Saturated
Arachidonic acid can be obtained by which 2 means?
a. Can be ingested primarily in animal fats
b. Manufactured in the body (Can be synthesized from linoleic acid (except in neurons), Can be
obtained from stores by breaking down membranes)
Which 3 factors influenced by Phospholipase predispose to cardiovascular disease?
a. Creates platelet aggregating factor and thromboxanes
b. Travels with LDL cholesterol
c. Hydrolyses oxidized phospholipids in LDL
Which neurotransmitter primarily stimulates Phospholipase A2?
Norepinephrine (Also serotonin mild)
Which prostaglandins are inflammatory and anti-inflammatory?
a. PG1, 3 – anti inflammatory
b. PG2 - inflammatory
What is the function of Leukotrienes?
Pain receptor sensitisation
What is special about the Delta 5 Desaturase enzyme (D5D)?
a. Prefers omega 3 FA resulting in low production of AA
b. Stimulated by insulin
What are the main symptoms associated with insulin dysfunction?
a. Peri-obesity
b. Dry mouth
c. Postural fatigue
d. Easily frustrated/stressed
e. High blood glucose
f. Fatigue 3-4pm
g. High cholesterol/triglycerides
h. Hungry/Tired after meals
What is type 3 diabetes and what is the insulin link?
a. Alzheimer’s
b. Insulin resistance = Alzheimer’s (direct correlation)
Give 3 ways early cardiovascular decline can be seen
a. Franks sign – loss of tissue in ear lobe leading to a distinctive fold forming on the lobe
b. Build-up of cholesterol around iris
c. Peri-obesity
How can pyrolurria alter pancreatic function?
Reduced HCl production can lessen exocrine pancreatic function
How can immune derived insulin dysfunction be differentiated from insulin resistance on labs?
a. Reduced ability to produce insulin in autoimmune dysfunction as opposed to excessive production
b. Antibodies to GAD enzyme
List 4 things that can be taken/eaten that can lead to insulin dysfunction
a. Gluten – autoimmunity leading to pancreatic destruction
b. Caffeine
c. Poor quality carbohydrates
d. High quantity carbohydrates
e. The pill
f. Trans fats
g. Potentially Long Chain Saturated fat
Describe key physical and AK examination findings of insulin resistance
a. Inhibition of pancreatic associated muscles (lats,triceps)
b. VRP tenderness
c. Increased waist circumference
d. Increased waist to hip ratio
e. Skin tags
f. Pigmentation changes
g. Dryness ulceration
How does caffeine influence Beta cell function? How is this seen in AK testing?
a. Caffeine drives Beta cell function
b. This can initiate inhibition associated pancreatic muscles
How does insulin influence oestrogen and testosterone production? What are the effects?
a. High insulin levels activate enzymes in the periphery that increase conversion of
i. Oestrogen to testosterone in women
ii. Testosterone to oestrogen in men
Why are most lab assessments for insulin dysfunction fundamentally flawed?
Most labs look for glucose regulation as a marker of insulin resistance. This is fundamentally flawed
as glucose metabolism can be normal due to excessive insulin levels or vice versa
What are 3 key dietary modifications that should be made for the insulin resistant patient?
a. Carbohydrate quality
b. Carbohydrate quantity
c. Increased Fat consumption
d. Increased protein consumption can help in some instances by providing building blocks for
receptor health
How can mitochondrial dysfunction be assessed and corrected using AK?
a. Aerobic and anaerobic challenge testing
b. Where there is an imbalance in anaerobic capacity vs aerobic then the individual needs to alter the
current exercise regime and carbohydrate intake to move the system more towards an ideal state
Give 3 mechanisms by which neural inflammation can be reduced
a. Luteolin, Resveratrol, cordyceps
b. Vagal stimulation
c. Improved barrier protection system
d. Improved blood glucose regulation
e. Improved neural excitation/cortisol production
At which location is the Blood Brain Barrier most vulnerable?
. Medial temporal lobe and cerebellum
