MODULE 5- ARPIN STUDY GUIDE Flashcards
nociceptors
unspecialized, free nerve endings
2 kinds of slowly transmitting afferent fibers
-Aδ lightly myelinated axons (first pain)
*type I
*type II
-C unmyelinated axons, small diameter (second pain)
are Aδ myelinated
lightly myelinated
are C myelinated
unmyelinated
-small diameter
foot/hand central pain pathway
foot/hand ->
DRG ->
dorsal horn of SC ->
VPL ->
S1
face central pain pathway
face ->
trigeminal ganglion ->
spinal nucleus ->
VPM ->
S1
pain + temperature is ipsilateral/contralateral
contralateral
what tract for pain + temperature
anterolateral tract
touch + pressure is ipsilateral/contralateral
ipsilateral
what tract for touch + pressure
dorsal column medial lemniscal tract
what results in pattern of dissociated sensory loss
-contralateral pain + temperature (anterolateral tract)
-ipsilateral touch + pressure (dorsal column medial lemniscal tract)
2 aspects of pain experience
-sensory discriminative
-affective motivational
what does sensory discriminitive pain include
VPL + VPM of thalamus
referred pain
-visceral (internal) pain can be felt as pain from other locations
-can also travel through the dorsal column-mediated lemniscal system
sensitivity to pain can be modified by which PERIPHERAL mechanisms
-hyperalgesia
-peripheral sensitization (inflammation)