Module 4 Drugs Part 2 Flashcards
Sympathomimetic bronchodilators–beta 2 agonists:
epinephrine - ephedrine - isoproterenol (Isuprel) - albuterol (Proventil MDI) - formoterol and salmeterol
“Front door” bronchodilators
Parasympatholytic bronchodilators–anticholinergic:
ipratropium (Atrovent)
“Back door” bronchodilators
Xanthine & methylzanthine bronchodilators:
caffeine - theobromine & theophylline - coffee - chocolate - green & black tea
“Side door” bronchodilators
diphenydramine (Benadryl) - cholopheniramine (Chor-Trimeton) - promethazine (Phenergen)
1st gen Antihistamines–used often now for sleep meds, etc
Claritin (loratadine)
2nd gen Antihistamine–only one still used
Allegra (fexofenadine) & Zyrtec (cetirizine)
3rd gen Antihistamines
Inhibiting these eicosanoids in the AA pathway helps reduce inflammation
I.e. SIngulair (montelukast)
Leukotriene rc blockers
Cromolyn sodium–formulated as a liquid nebulizer (inhalation)
Mast Cell Stabilizers
Receiving weekly shots of pregressively higher concentrations of theallergenes a person is allergic to in order to buildup blocking IgG antibodies (for the IgE antibodies)
Desensitization shots for immunotherapy
beclomethasone (Vanceril MDI), fluticasone (Flovent MDI) & triamcinolone (Azmacort MDI)
Inhaled corticosteroids
Codeine & all other opioids - DMX/dextromethorphan (Robitussin) - (morphine, codeine, and hydrocodone) - Phenergan (promethazine–used in the Robitussine line)
Antitussives
The most popular OTC expectorant/mucolytic; thins mucous and helps it be coughed up
guaifenesin
Pen VK - amoxicillin - clarithromycin (Biaxin) - azithromycin (Zithromax) - ciprofloxacin (Cipro)
Oral antibiotics
systemic drugs (to be used in lungs):- fluconazole (Diflucan) - terbinafine (Lamisil)
Pulmonary antifungals
Oral drugs Relenza & Relenza - TIV (influenza vaccine)
Antiviral agents
Nicotine gum - nicotine patch - the antidepressant bupropion (Zyban, Wellbutrin) - Chantix (varenicline)
Anti-smoking drugs
A miscellaneous drug: a surfactant extracted form ground-up cow lungs used to treat lung disease of premature infants (hyaline membrane disease)
Survanta
Ortho tri-cyclin - Enovid - Lybrel - Yaz -
Oral Contraceptives
a triphasic pill also approved for acne treatment
Ortho tri-cyclin
the first oral contraceptive marketed in the U.S.
In 1960 was progestin-only drug
Enovid
the only OC approved for eliminating periods
Lybrel
the only OC approved for treatment of PMDD and moderate acne
*new estrogens have 7x the risk of stroke as older COCPs
Yaz
1 type estrogen and 1 type of progesterone
Monophasic
1 type of estrogen and 2 types of progesterone
Biphasic
1 type of estrogen and 3 types of progesterone
Triphasic
the high dose, progestin-only drug used for emergency contraception (contains the 2nd generation progestin ‘levonorgestrel’)
Plan B
Depo-Provera (medroxyprogesterone) - Ortho Evra - NuvaRing - IUDs- Norplant system
Non-oral contraceptives
monthly injections; progestin-only
Depo-Provera (medroxyprogesterone)
transdermal patch contraceptive
Ortho Evra
a flexible plastic vaginal ring that releases a low dose of combined progestin and estrogen over 3 weeks
NuvaRing
IUDs - Norplant system
Implantable contraceptive devices
silicone impregnated implant: 1 or 2 small devices placed under the skin that emit a progestin drug; good for 3 years
Norplant system
Drugs that cause a medical abortion (vs. a surgical/suction/vaccum abortion)
Abortifacients
an abortifacient: a potent antiprogesterone drug that causes powerful uterine contractions
- developed in France
- also called RU-486
mifepristone (Mifeprex)
Premarin - ethinyl estradiol or E2
MHT–menopausal hormone therapy:
post-menopausal estrogen replacement
a mixture of conjugated estrogens isolated from equine sources
Premarin
the main (natural) female estrogen
ethinyl estradiol or E2
synthetic progesterone-like drugs
Progestins
natural progesterone
the main female progestogen
progesterone - Provera (medroxyprogesterone) - megestrol (Megace) -levonorgestrel - drospirenone
Progestogens & Progestins
Provera (medroxyprogesterone)
a synthetic progestin
a progestin for the treatment of wasting syndrome
megestrol (Megace)
the 2nd generation progestin used for emergency contraception brith control pills (Plan B)
levonorgestrel
4th generation progestin used in Yaz
drospirenone
Calcium supplements - MHT with conjugated estrogen (Premarin) - alendronate (Fosamax) - SERMs: Evista (raloxifene)
Drug therapy for osteoporosis
most calcium supplements are combined with ____
Vitamin D
bisphosphonates that inhibit bone resorption by suppressing osteoclastic activity in the bone
alendronate (Fosamax)
selective estrogen rc modulators–SERMs
Evista (raloxifene)
vaginal yeast infections - bacterial vaginosis (BV) -
disturbances of vaginal flora
clotrimazole (Gyne-lotrimin) - miconazole (monistat) nystatin (Mycostatin)
drugs to treat yeast infections
infection of the vagina caused by anaerobic bacteria
BV-bacterial vaginosis
oral metronidazole (Flagyl) - metronidazole gel (MetroGel - clindamycin (Cleocin) oral or vaginal ovules
antibiotics to treat BV
Sulfas: sullfanilamide & combo drugs trimethroprim-sulfamethoxazole (Bactrim DS, Septra DS)
standard antibacterials for uncomlicated, non-recurent UTIs
sulfa drugs - penicillins - cephalosporins - fluoroquinolones - macrolides - tetracyclines - nitrofurantoin (Macrodantin) - the aminoglycoside gentamicin - cranberry juice
drugs to treat UTIs & STIs
ampicillin, amoxicillin, Pen G, procaine penicillin (Bicillin–a long acting injectable
penicillin drugs for UTIs/STIs
cephalexin (Keflex) - ceftriaxone (Rocephin)
cephalosporins for UTIs/STIs
ciprofloxacin (Cipro) - levofloxacin (Levaquin)
Fluoroquinolones for UTIs/STIs
erythromycin (EES) - azithromycin (Zithromax)
Macrolide antibiotics for UTIs/STIs
minocycline (Minocin)
tetracycline antibiotic for UTIs/STIs
drug used for prophylaxis of UTIs
nitrofurantoin (Macrodantin)
drug for severe kidney infections
the aminoglycoside (gentamicin)
contains tannins (proanthrocyanidins) with proven benefits for UTIs
cranberry juice
acyclovir (Zovirax) - Famvir (famciclovir) - Gardasil vaccine
antiviral agents for STIs caused by Herpes Simplex Virus
comes in both topical preparations for cold sores and oral preoparations for genital herpes
acyclovir (Zovirax)
A better choice for once/day antiviral therapy; more convenient
Famvir (famciclovir)
the vaccine for the prevention of HPV genital warts in men and women ad prevention of cervical cancer in women
Gardasil
a urinary analgesic and OTC remedy that will relieve symptoms but not treat the underlying infection; should only be used temporarily
Pyridium (phenozopyridine)
anticholinergic drugs like Ditropan (oxybutynin) & Vesicare–to treat “leaking pipes”
antispasmodic drugs for urinary incontinence or overactive bladder
Viagra (sildenafil) - Cialis (tadalafil) - Levitra (vardenafil)
PDE5 inhibitors for ED-erectile dysfunction