Module 4

Question 1

Rules that explain the common patterns of single-gene transmission

Answer 1

Modes of inheritance

Question 2

Passing of a trait depends on whether:

Answer 2

• Determining gene is on an autosome or on a sex chromosome
• Allele is recessive or dominant

Question 3

*Affects both sexes and appears every generation

Answer 3

Autosomal Dominant Inheritance

Question 4

What disease is an example of Autosomal Dominant Inheritance

Answer 4

Huntington’s disease

Question 5

*Males and females can be affected.
*Affected males and females can transmit the gene, unless it causes death before reproductive age.
*Trait can skip generations.
*Parents of an affected individual are heterozygous or have the trait.

Answer 5

Autosomal Recessive Inheritance

Question 6

what disease is an example of Autosomal Recessive Inheritance

Answer 6

Cystic fibrosis

Question 7

which mode of inheritance is the following Punnett square?
Hh = affected
hh = normal

Answer 7

Autosomal Dominant Inheritance

Question 8

which mode of inheritance is the following Punnett square?
Hh = carrier
hh = affected

Answer 8

Autosomal Recessive Inheritance

Question 9

Affected individual has an affected
parent, unless he or she has a de
novo mutation

Answer 9

Autosomal Dominant

Question 10

Affected individual has parents who
are affected or are carriers
(heterozygotes)

Answer 10

Autosomal Recessive

Question 11

X-linked traits are passed like
autosomal traits

Answer 11

Females

Question 12

A single copy of an X-linked allele causes expression of the trait or illness

Answer 12

Males

Question 13

Human male is considered _________ for X-linked traits

Answer 13

hemizygous

Question 14

-Always expressed in the male
-Expressed in a female homozygote and very rarely in a female heterozygote
-Affected male inherits trait from heterozygote or homozygote mother
-Affected female inherits trait from
affected father and affected or
heterozygote mother

Answer 14

X-Linked Recessive Trait

Question 15

-Expressed in females in one copy
-Much more severe effects in males
-High rates of miscarriage due to
early lethality in males
-Passed from male to all daughters
but to no sons

Answer 15

X-Linked Dominant Trait

Question 16

What X-Linked Trait is the following?
XRXr = Affected Female
XRY = Affected male
XrXr = Normal female
XrY = Normal Male

Answer 16

X-Linked Dominant

Question 17

What X-Linked Trait is the following?
XRXC = Normal Female
XCY = Normal Male
XCxc = Carrier Female
XcY = Affected Male

Answer 17

X-Linked Recessive

Question 18

Genes on the Y chromosome are said to be ________

Answer 18

Y-linked

Question 19

symbolic representations of
family relationships and the transmission of inherited traits

Answer 19

Pedigrees

Question 20

A diagram that shows the occurrence and appearance or phenotypes of a particular gene or organism and its
ancestors from one generation to next

Answer 20

Pedigree Chart

Question 21

• Describes the process of interpretation of information displayed as a family tree or chart
• Used to work out the probability that someone in a family will inherit a condition

Answer 21

Pedigrees

Question 22

True or False

A father transmits his allele of X-linked genes to his daughters, but not his sons

Answer 22

True

Question 23

True or False

A mother transmits an allele of X-linked genes to both her daughters and her sons

Answer 23

True

Question 24

Does not skip generations, can affect both sexes

Answer 24

Autosomal Dominant Trait

Question 25

• Trait is rare in pedigree
• Trait often skips generations (hidden in heterozygous carriers)
• Males and females equally likely to be affected

Answer 25

Autosomal Recessive Trait