Module 4 Flashcards
Function of the endocrine system
Controls the secretions of hormones from several glands throughout the body
Glands
Organs that secrete or release hormones into the bloodstream.
Hormones
Chemical substances released from gland in small amounts
Chemical messengers that transfer info and instructions from one area of the body to another.
What factors do glands and hormones influence? (6)
Growth and development
Tissue formation
Metabolism
Homeostasis
Sexual function
Mood
Endocrinologist and endocrinology
-physician that diagnosis and treats conditions of endocrine system
- study of the endocrine system; subspecialty of internal medicine
Name the 8 major glands of endocrine system
Pituitary
Pineal
Thyroid
Parathyroid
Pancreas
Adrenals
Ovaries,testes
Thymus
Location and function of the pituitary gland?
Base of the brain, under the hypothalamus
Master gland; regulates other endocrine glands
Location and function of the pineal gland?
Brain
Regulates sleep
Location and function of the thyroid gland?
Neck (anterior)
Metabolism, growth and development
Location and function of the parathyroid gland?
Neck (posterior)
Maintains calcium (increase calcium blood levels) and phosphate levels
Location and function of the pancreas ?
Epigastric area of abdomen
Blood glucose regulation
Location and function of the adrenals ?
Abdomen, above the kidneys
Regulate sodium and potassium, carbohydrate metabolism, sex hormones, epinephrine secretions in emergencies
Location and function of the gonads?
Pelvis
Male and female secondary sex characteristics
Location and function of the thymus?
Mediastinum
Regulates the immune system
Divisions of the pituitary gland
Adenohypophysis and neurohypophysis
Hormones secretes by adenophyophysis
Growth hormone (GH)
Adrenocorticotropin Hormone (ACTH)
Thyroid-stimulating Hormone (TSH)
Follicle stimulating Hormone (FSH)
Luteinizing Hormone (LH)
Prolactin Hormone
Melanocyte stimulating hormone
Growth Hormone
Regulates growth and development of the bones and muscles, and other organs
ACTH
Regulates the growth of the adrenal cortex
TSH
Stimulates growth of the Thyroid gland
FSH and LH
Controls the sex glands in males and females
Prolactin hormone
Stimulates the growth and development of the mammary gland.
Melanocyte stimulating hormone
Controls skin pigmentation
Target organs of the adenohypophysis hormones
TSH: thyroid gland
ACTH : adrenal cortex
FSH and LH: testes and ovaries
Prolactin: breast
GH: liver, bone, muscle,organs
Hormones by the neurohypophysis?
Antidiuretic hormone (ADH)
Oxytocin
ADH
Regulates the secretion or reabsorption of water in the kidneys
Oxytocin
Stimulates the uterus to contract during childbirth
And the release of milk from the mammary glands
Pineal gland hormones
Melatonin
Serotonin
Melatonin
Regulates the body’s sleep-wake cycle
Serotonin
Stimulates the nervous system by releasing neurotransmitters, smooth muscles and gastric secretions
Hormones of the thyroid
Thyroxine (T4)
Triiodothyronine (T3)
Calcitonin
T4 and T3
Maintains and re guy lates the basic metabolic rate of the body, growth and development , and metabolism of nutrients, water, vitamins, and minerals
Calcitonin
Involved in bone and calcium metabolism
(Lowers the blood calcium levels)
Parathyroid gland hormone and it’s function?
Parathyroid hormone (PTH)
Maintaining calcium levels and the metabolism of phosphorous
Islets of langerhans
Endocrine portion of the pancreas that consist of cell clusters
What hormones does the islets of Langerhan secrete?
Insulin
Glucagon
Somatostatin
Function of insulin, glucagon, and somatostatin?
Insulin: stimulates cells to take in glucose from bloodstream for metabolism
Glucagon: breaks down glucagon to glucose, increasing blood glucose levels
Somatostatin: decrease production of insulin and glucagon
Gastrointestinal mucosa
Epithelial lining of the stomach and intestine; secretes several hormones related to digestion
Four hormones of the gastrointestinal mucosa
Gastrin
Secretin
Cholecystokinin
Enterogastrone
Gastrin
Stimulates production of gastric acid in the stomach
Secretin
Stimulates the secretion of pancreatic enzymes, bile, and other secretions from the intestines involved in digestion of food.
Cholecystokinin
Controls the gallbladder
Enterogastrone
Regulates secretions from the stomach
Two parts of adrenal glands ?
Adrenal cortex (outer portion)
Adrenal medulla ( inner portion)
3 type of hormones from adrenal cortex
Glucocorticoids
Mineralocorticoids
Androgens
Function and examples of Glucocorticoids
Involved in carbohydrate metabolism
Cortisol
Corticosterone
Function and example of mineralocorticoids?
Regulation of electrolytes and fluid balance
Aldosterone
Function and example of androgens?
Stimulates the development of male sex characteristics.
Testosterone and androsterone
Hormone secreted by adrenal medulla
Catecholamines
Function and example of catecholamines?
Involved in nervous system regulation; involved in sympathetic nervous system function.
Dopamine
Epinephrine
Norepinephrine
Structures and the gonads
Ovaries
Testes
Placenta
Hormones released by the sex organs
Ovaries: estrogen and progesterone
Testes: testosterone
-regulates female and male sex organs
Placenta
Temporary endocrine organ that secrete hormones involved in the growth and development of the fetus.
Hormones secreted by the thymus
Thymosin
Thymopoietin
Cushing Disease
When adrenal cortex produces too much of the hormone cortisol.
Common causes of Cushing disease
Tumor in the adenohypophysis or a tumor in the adrenal gland
Cushing disease symptoms
Muscle weakness, fatigue, mood swings, and easy bruising
Physical exam signs of Cushing disease
Hypertension
Fat deposits in the face
Buffalo jump
Hirsutism
Edema
Skin discoloration
Osteoporosis
Diagnosis and treatment of Cushing disease
Diagnosis made by testing cortisol levels in the blood
Tumors may need surgical resection
Wean off corticosteroid if patient is using.
Diabetes mellitus
Disease with abnormal glucose metabolism
- when insulin is either not produced by the pancreas or the cells of the body do not respond to insulin
Two types of diabetes mellitus
IDDM: beta cells of pancreas no longer produce insulin
NIDDM: cells do not respond to insulin
Diabetic keto acidosis
Condition where the body is using fat as a source of fuel, rather than carbohydrates
Early manifestation symptoms of diabetes?
Polyuria
Polydipsia
T1: polyphagja, fatigue, weight loss
T2: blurred vision
Complications of Diabetes mellitus
Hyperglycemia
Hypoglycemia
Gangrene, foot ulcers
Cataracts, glaucoma, retinopathy
CAD, stroke
Hypertension, renal failure, albuminuria
UTI, impaired healing, chronic skin disease
Hyperthyroidism (definition and causes)
Excess of thyroid hormone secreted by thyroid gland
Causes:
Graves’ disease
Toxic multi modular goiter
Thyroiditis
Benign or malignant tumors
Graves’ disease
Autoimmune disease where antibodies stimulate the thyroid to produce too much T4
Toxic multinodular Goiter
Enlargement of the thyroid gland that then produces too much thyroid hormone.
Symptoms of hyperthyroidism
Hyperactivity
Nervousness
Irritability
Sweating
Palpitations
Tachycardia
Intolerance to heat
Weight loss
Diarrhea
Easy fatigue
Hyperthyroidism treatments
Medications
Radio-iodine treatments that destroy the thyroid tissue
Partial thyroidectomy
Hypothyroidism definition and causes
Deficiency of thyroid hormone
Causes: Hashimoto’s thyroiditis
Treatments for hyperthyroidism
Radiation treatments
Thyroid surgery
Certain medications
Symptoms of hypothyroism
Fatigue
Weakness
Dry skin
Intolerance to cold
Bradycardia
Hair loss
Weight gain
Dyspnea
Treatment for hypothyroidism
Supplementation with synthetic thyroid hormone
Misc symptoms of hypothyroidism and hyperthyroidism
Function of nervous system
-Coordinates all the activities of the body
-Received info from sensory receptors and then uses this info to coordinate the activities of the muscles, organs, and glands to maintain homeostasis.
Neurology
Neurologist
Neurosurgeon
Two divisions of the nervous system
CNS: brain and spinal cord
PNS: connects CNS to the rest of the body
What protects the CNS
Protected by the skull, vertebrae of the skeletal system, and the meninges
Layers of the meninges
Dura mater
Arachnoid mater
Pia Mater
Cerebrospinal Fluid
Produced by the ventricles of the brain
Surrounds the brain and spinal cord; cushions and protects these structures from shock.
Main parts of the brain
Cerebrum
Cerebellum
Diencephalon
Brain Stem
Cerebrum
Contain nerve centers that control all sensory and motor activity, memories, consciousness, emotions, and voluntary movement
Cerebellum
Coordinates sensory perception and motor output
Parts of the diencephalon
Thalamus
Hypothalamus
Thalamus
Relay center for incoming sensory and motor impulses
-sends messages onto the cerebrum
Hypothalamus
Regulates the autonomic nervous system
Serves has a connection between ANS and the nervous system