Module 4 Flashcards
3 Factors Affecting Stroke Volume
Contractility
Pre load
After load
Types of shock
Anaphylactic Pulmonary Cardiogenic Hypovolemic Septic
Scope of Perfusion
Optimal –> Suboptimal –> No Perfusion
Types of Hypertension
Primary
Secondary
Primary Hypertension
Hypertension that occurs without an identified disease
Obscure causes
Secondary Hypertension
Hypertension that occurs as a result of an identified disease
Short Term Regulators of Blood flow
Neural
Cardiovascular Center –> receives input from baroreceptors + chemoreceptors
Hormonal
RAAS System –> angiotensin II, aldosterone
Vasopressin (ADH)
Epinephrine/Norepinephrine
Local
Blood vessel autoregulation
Longterm Regulators of Bloodflow
Kidneys
resp for filtering blood, reabsorption, excretion
Target-Organ Damage from Hypertension
Heart
Brain
Eyes
Kidneys
Cholectamine
Chemical messenger released into blood in responset to stress
Examples of Cholectamine
Epinephrine
Norepinephrine
Contractility
force of myocardial contraction
determined by preload
Afterload
Resistance that must be overcome to eject blood from the left ventricle
impacted by blood viscosity, vasoconstriction
Mean Arterial Pressure
Average pressure of the arterial system through one cardiac cycle
Used as an indicator of perfusion
calculated by: cardiac output x total peripheral resistance
~60-100 mm Hg
Systolic vs. Diastolic Blood Pressure
Systolic BP = blood pressure in arteries during ventricular contraction
Diastolic BP = blood pressure in arteries during ventricular relaxation
Pulse Pressure
Measures pulsing nature of blood flow
Calculated by: systolic BP - diastolic BP
~40 mm HG
Peripheral Vascular Resistance
Resistance to blood flow in the systemic arteries
Heart Conduction System
SA Node –> AV Node –> AV Bundle –> Purkinje Fibers
Autoregulation
ability of organs to maintain optimal perfusion despite changes in blood pressure
local effect
High Blood Pressure
systole = >140 diastole = >90
Diuresis
excretion of water/extracellular fluid by kidneys
Natriuresis
excretion of sodium by kidneys
Consequences of High SBP
leads to left ventricular hypertrophy
heart failure
Hypertensive Crisis
systole = >180 diastole = >110
includes hypertensive urgency and hypertensive emergency
Secondary Hypertension Risk Factors
Kidney disease
Adrenal Cortical disease
Pheochromocytoma
Coarctation of aorta
Consequences of High DBP
decreased coronary perfusion
increases total peripheral resistance
Secondary Hypertension Risk Factors
Kidney disease
Adrenal Cortical disease
Pheochromocytoma
Coarctation of aorta
Kidney Disorders
Acute glomerulonephritis
Acute renal failure
Acute urinary obstruction
Atherosclerosis of renal blood vessels
Total Peripheral Resistance
Total resistance to blood flow in systemic circulatory system
Angiotensin II Effects
vasoconstrictor
promote reabsorption of sodium in proximal convoluted tubule
stimulate adrenal cortex to produce aldosterone