Module 3.1 and 3.2 Flashcards

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1
Q

dUnicellular / singlecellular organism (amoeba)
-fresh water ponds

A

-all organisms re constanlty , eschaning materials , with their enviornment .
-e.g , amoeba carries out aerobic respirattion generae atp .
-oxygen , needed for aerobic respiration —> diffuses into he cel through the cell membrane .

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2
Q

-scientists call the cell membrane an exchange surface .
-when amoeba carries our respiration , it prouduces the gas co2 .
-this co2 diffuses out of the cel via the cell membrane ,

A

In microscopic organsisms _ amoeba organism , exhange all the substance it needs directly though the cell memerbane , There is two reasons for this .

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3
Q

reason one

A

-microsocopic organisms , relatively low rate of respiration as ehya rent ery active organsimss .

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4
Q

reasons two

A

relatively large compared to volue of the cell . SA:V ,
-calcukae sa;v ratio using this equation

s:volume ratio = surface area / volume

sa;v=24/8 =3:1 96/64=1.5:1 for example

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5
Q

-single cell organsisms have a large sa to volume ratio .

A

they can transfer all of the chemicals they need across the cell membrane .
-However , large multiceullar orgasims sa;V much less .

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6
Q

-some small multicellular organsisms do rely on diffusion across their body e.g flatowrm .

A

by evolvingg a very flat and thin body size all of the cells in the flat are clsoe to the surfce .
-so diffusion corss hte body urfce is sufficne in a fla surface .

-HOWEVER , LARGE MULTICeullar organsims sa : v can not what .
-So multiceullar organsism evovles two specialsied sytems to compensate .

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7
Q

evolving one

A

-evovled specialised gas exchange sytems –> very large surface area ( lungs in mammals gulls in gish .

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8
Q

evovling two

A

specialsied transport sytem to carry moelcules around their bodlood

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9
Q

Mammals have a very low surface to volume ratio .
-mammals are also very active animals , mammals maintain a constant body temp .

A

-this required , an increased rate of aerobic respiration .
for these reasons , mammals have an extremely high oxygen demand .

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10
Q

-mammals , get their oxygen from the air , via their lungs shown , structure of human breathing system .

A

-humans have two lungs which are found in the thorax chest activity .
-the lungs are protected by the ribs .
-The ribs also plays a role in breathing .
-Along , with the intercostal muscles and diaphragm .

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11
Q

stage one of breathing

A

-when humans breathe though their nose , air passes through the nasal cavity .

-hairs in the nasal cavity traps , dust particles and pathogens .
-the nasal cavity also warms and moistens the air before it enter the lungs .

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12
Q

stage two of breathing

A

-The air , then makes it way down a wide tube called the trachea .
-The air then makes it way down a wide tube calle the trachea .

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13
Q

the trachea two key adaptations which you need to learn .

A

-walls of the trachea contain cartilage which is a firm but flexible material .
-The cartilage prevent the walls of the trachea , for collapsing when we inhale .

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14
Q

-this diagram shows a view of the trachea looking down towards the lungs .

A

-as you can see the trachea is very close to the oesophagus , which is the tube carrying food to the stomach .
-Yu’ll notice that the cartilage in the trachea forms a c shape , rather than forming the complete rings ?

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15
Q

Why does it not form complete rings ?

A

The absence if cartilage in the region near the oesophagus allows the food to pass down the oesophagus easily .

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16
Q

What is the second adaptation of the trachea

A

The walls are lined with ciliated epithelial and goblet cells .
-Showing cells lining the walls of the trachea .

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17
Q

What s the role of goblet cells

A

Goblet cells secrete mucus which traps dust particles and pathogens .
-The ciliated epithelial cells have cilia extending from the cell membrane .
-T

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18
Q

What do the cilia do ?

A

The beating of the cilia moves the mucus to the throat .
-The mucus is then swallowed and the dust and pathogens are digested by the stomach enzymes .

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19
Q

Going back to our lungs , we can see trachea divide into two bronchi

A

two bronchus carries air into one of the lung .
-Just like the trachea , the bronchi contain cartilage ciliated epithelial and goblet cells .

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20
Q

What does each bronchus split into ?

A

Each bronchus splits forming progressively narrower airways called bronchioles .
-The walls of larger bronchioles are supported by cartilage , they also contain smooth muscle .

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21
Q

What happens when the smooth muscle reflexes ?

A

The bronchioles widen allowing more air to pass into the deeper part of the lungs .

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22
Q
A
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23
Q

Deep in the lungs the bronchioles are extremely narrow .
What do these bronchioles lead to ?

A

Air sacs , called alveoli .
-Alveoli are the sites of gas exchange .
-There are hundreds of millions of alveoli in the lungs . The internal walls of the alveoli are covered with a thin layer of moisture .

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24
Q

-Close up of the alveoli , the alveoli is covered with blood capillaries .,
What happens to the oxygen in the air ?

A

Oxygen in the air of the alveoli dissolves nt he mositure on the inside of the alveoli wall .
-The oxygen then diffuses into the red blood cells where it combines with haemoglobin .
-Carbon dioxide diffuses from the blood into the alvelar spcae .

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25
Q

Between the alveoli , are elastic fibres which stretch and recoil during breathing .

A

As we have seen , the alveoli is where gases diffuse in and out of the blood .

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26
Q

What is one way alveoli are adapted to maximise the rate of diffusion .

A

Hundreds of millions of alveoli , these provide a massive surface area for the diffusion of gases .

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27
Q

Check sheet for the close up of alveolus and blood capillaries .

A

Both he wall of the alveolus and the walls of the capillary are only one cell thick .
-This means there is a very short diffusion distance between the air in the alveolia nd red blood cells in the capillary .

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28
Q

The narrow diameter of the capillary means that the red blood cells are close tot he capillary wall .

A

This minimises diffusion distance .

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29
Q

The extensive capillary network means that once oxygen diffuses into the blood , what happens ?

A

It is rapidly carried away from the alveoli -This ensures there is always a steep concentration gradient for oxygen .

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30
Q

Co2 also has a steep concentration gradient ,a s more is continually brought to the alveoli int he blood stream .

A

these concentration gradients are also maintained by breathing , which brings fresh air into the alveoli .

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31
Q

This ensures there is always a high concentration of oxygen in the alveolar air .

A

as well as a low concentration of co2 , this helps to ensure a rapid rate of diffusion of these gases .

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32
Q

What is breathing also known as ?

A

Ventilation .
-Ventilation brings fresh air from outside of the body into the alveoli .
-THIS , increases the concentration of oxygen in the alveoli air spaces whilst decreasing the concentration of co2 .
-The effect of this , is to increase the concentration of these gases thus increasing the rate of reaction .

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33
Q

What is the mechanism for ventilation ?

A

Simplified version of the lungs .
-Ventilation involves the action of two sets of muscles .

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34
Q

Muscle one involved in ventilation

A

intercostal muscles - which lie between the ribs and the diaphragm .
-Which separates the thorax (chest cavity ) from the abdomen .
-The two sets of muscles work together to change the volume of the thorax .
-

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35
Q

What happens if we change the volume of the thorax ?

A

By changing the volume of the thorax , this changes the pressure of air in the lungs .
-The effect of this , is to draw air into the lungs (inhalation ) . Or to expel air from the lugs (exhalation )

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36
Q

There are the two sets of intercostal muscles . What are they ?

A

These are called the external and internal intercostal muscles as they are involved in regular breathing . focus on external
-The internal intercostal muscles are involved in stronger breathing , this is what happens when we inhale / breathe in .

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37
Q

Stage one of inhalation

A

during inhalation ,t he external intercostal muscles contract aka they shorten .
-this pulls the ribs upwards and outwards l

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38
Q

stage two of inhalaiton

A

at the same time ,t he diaphragm also contracts which causes it tot flatten . The effect of these is to increase the volume of the thorax and lungs .
-This reduces the air pressure in the lungs .

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39
Q

stage thee of inhalation

A

as the air pressure in he lungs is now less than atmosphere pressure , air is drawn into he lungs .
-air is moves into the alveoli and the elastic fibres between the alveoli stretch .

BECAUSE - inhalation involve muscles constrain , inhalation active process .

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40
Q
A
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41
Q
A
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42
Q

Stage one of exhalation

A

during regular breathing , exhalation is essentially process as the muscles relax .
-Therefore exhalation does not require a great deal of energy .

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43
Q

stage two of exhalation

A

-during exhalation ,the external intercostal muscles relax and return to their original length .

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44
Q

stage three of exhalation

A

the diaphragm also relaxes returning to its usual dhape .
-The effects of this is to reduce there volume of the thorax and lungs .
-now air pressure in the lungs is gretaher than atmospehrec pressure .
-air ispushed out of the lugns .

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45
Q

-The elastic fibres between the alveoli also recoil helping to push out he air

A

scientists call this elastic retraction .

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46
Q

volume of lungs changes when we inhale and exhale

A
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47
Q

lungs are surrounded by a pleural membrane .
what do theyd o ?

A

between these membranes there is plural fluid which acts as a lubricant as the lung volume changes

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48
Q

As we have seen . during regular breathing exhalation is mainly a passive process .

A

This is not the case ,when we exhale strongly , as during this internal intercostal macules contract as we exhale strongly .
-this pulls the ribs down and inwards forcing air out of the lungs .

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49
Q

At the same time , the external intercostal muscles relax

A

As the internal intercostal muscles relax which the external interoctysal muscles contract . Scientists descrier this as antagnote .

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50
Q

What are bony fish and give examples

A

They are a large group of fish which have evolved a skeleton made of bone

Tuna salmon cod and trout

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51
Q

Whag js the significant issue when it comes to gas exhange in fish ?

A

Bony fish are large and active organisms with a very high oxygen requirement
-because of their large size they have a very low surface area to volume ratio .
2. The SCALY surface of bony fish does not allow gasses to pass through

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52
Q

How do fish get their oxygen ? But what is problem

A

From the water , but concentration of oxygen in the water is MUCH LOWER than in air .
So for these reasons , bony fish have evolved a specialised gas exchange system . Which extracts MAZOMUM AMOUNT of oxygen from water

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53
Q

Bony fish have a flap of tissue on either side , slightly behind their head function ? .

A

This is called operculum I’m and we have behind this the operculum cavity .

INSIDE the operculum cavity , we find gills .

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54
Q

S1 gas exchange in fish

A

Oxygen rich water enters the fish through the mouth

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55
Q

S2 gas exchange in fish

A

Water then passes over the gills ,
In gills oxygen diffuses from the water into the blood . And carbon dioxide diffuses from the blood into the water .

Finally water passes through the operculsr opening .

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56
Q

Structure of gills ( go all the way to card 397 to continue then come back to do insects )

A

gills consists of several bony arches , extending from each gill arch are a large number of gill filaments .

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57
Q

Insects can be extremely active organisms so what would there oxygen demand be like ?

A

They would have a very high oxygen demand , for example , during flight .

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58
Q

Key , how have gas exchange systems evolved in insects ?

A

to provide oxygen directly to cells .
-although insects do have a specialised transport system , this transfers nutrients and not oxygen .

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59
Q

What are insects covered with ?

A

A protective exoskeleton made of the polysaccharide chitin .
-Gases such as oxygen and carbon dioxide do not easily pass though .
-so on the surface of the exoskeleton ,t here are small openings called spircales .

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60
Q

What do spiracles do ?

A

Spiracles allow gases such as oxygen and carbon dioxide to diffuse into the body of the insect .

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61
Q

What can spiracles leads to ?

A

Spircales can lead into a network of tubes called the trachea .
(trachea are relatively wide tubes with a diameter of around 1 mm) .

-trachea extends down into the body of t he insect .
-trachea are relatively wide tubes with a diameter of around 1 mm .

-trachea extends down and along the insect’s body .

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62
Q

what is the trachea reinforced with

A

spirals of chitin .
-the chitin prevents the trachea from collapsing example when an insect moves .

-extending from the trachea are very fine tubes called tracheoles .

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63
Q

What are the adaptations of tracheoles ?

A

Tracheoles have a diameter of around 1 micrometre , or less .
-In fact they are much narrower than shown in the diagram .
-each trachea is a single cell that has extended to form a hollowtube .

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64
Q

insects

A

-a huge number of tracheoles extend down inbetween the cells of the insects body .

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64
Q

adaptations 2 of tracheoles

A

unlike trachea , tracheoles are not supported by chitin .
-This is because tracheoles have such a narrow diameter and are extremely close to cells , there is a very short diffusion distance for gases moving between the cells and the tracheoles .

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65
Q

adaptation 3 of tracheoles

A

huge number of tracheoles provide a very large surface area for gas exchange .

-this allows insects to maintain a very rapid rate of aerobic respiration ( example flight ) .

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66
Q

What are the ends of the trachea filled with ?

A

They are filled with fluid also known as tracheal fluid .
-during intense activity , the cells around the tracheoles undergo anaerobic respiration .

-anaerobic respiration which produces lactic acid lowering the water potential of the cells .

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67
Q

what does lowering the water potential of cells do to the tracheal fluid ?

A

causes the water in the tracheal fluid to move into the cell .
-this reduces the volume of the tracheal fluid drawing air into the tracheoles .
-also shows more tracheole surround avoidable for diffusion of oxygen and carbon dioxide .

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68
Q

Is gas exchange active or passive in insects ?

A

It is essentially a passive process .
This is because , oxygen diffuses down its co2 gradient from a high concentration in the external air into the lower concentration .

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69
Q

describe co2 diffusion in insects

A

co2 , diffuses down its conc tracheoles gradient .
-with a relatively high concentration in the tracheoles out to the external air .

rate of diffusion decreases with distance meaning insects tend to be small .

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70
Q

smaller size of insects , reduces distance required for diffusion to take place .

A

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71
Q

However , what is one problem that insects have ?

A

This is loss of water .
-The walls of the tracheoles are moist and the ends contain tracheal fluid .

-Meaning , water vapour can diffuse out of an insect via the spiracles .

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72
Q

However , what is one problem that insects have ? (2)

A

muscular sphincter .

-This means insects can reduce water loss by closing their spiracle (example insects oxygen req)

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73
Q

ocr , –> how have some insects evolved to increase rate of gas exchange ?

A

-If , we look at insects ,w e can see they have three main body segments .
Head –> Thorax–> Abdomen
-Some insects can also contract muscles to change the volume of the thorax and abdomen .

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74
Q

ocr , –> how have some insects evolved to increase rate of gas exchange ? (2)

A

causing , pressure changes in the trachea pushing air in and out .
-this bulk movement is called mass movement .

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75
Q

-in some insects , the trachea contain expanding sections called air sacs .
-What are the adaptations of the air sacs ?

A

-changes in the volume of the thorax and the abdomen can squeeze the air sacs , causing air to move from the air sacs into the tracheoles . -insects can also use the oxygen in the air sacs during when the spiracles have been closed for water conservation .

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76
Q

Larger organisms , have a much lower surface area to volume ration , so what does this mean ?

A

The vast majority of cells are a large distance from the surface of organisms .

-also , large organsisms , are often , very active , and have a high demand of oxygen for aerobic respirations /

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77
Q

so , if larger organisms , cannot rely on diffusion alone for the exchange of material , what else do they rely on ?

A

-we have already seen , how insects fish and humans have specialised gas exchange systems .

-This ensures a very efficent gas exchnage sytem for oxygen and carbondioixde .

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78
Q

how have insects adapted to their gas exchange system ?

A

so that gases diffuse directly .

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79
Q

How does diffusion work in fish and humans ?

A

gases dissolve in blood , which acts as a transport system .
-The blood then moves around the circulatory system , transferring the gases between the cells and
the gas exchange system .

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80
Q

what else does blood transfer , other than oxygen ?

A

Other essential molecules like glucose and amino acids .
-when molecules are carried in a transport medium such as blood through a circulatory system , scientists call this mass transport .

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81
Q

circulatory system of fish (1)

A

deoxygenated blood , is pumped by the heart , through the blood vessels to the gills .

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82
Q

circulatory system of fish (2)

A

In the gills , blood passes though narrow blood vessels called capillaries .

-oxygen diffuses from the water into the blood .

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83
Q

circulatory system of fish (3)

A

the oxygenated blood now passes from the gills though the blood vessels to the body tissues .

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84
Q

circulatory system of fish (4)

A

when it reaches the body tissues , the blood again passes though narrow capillaries , where oxygen diffuses from the blood to the cells that needd it .

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85
Q

circulatory system of fish (5)

A

finally , the deoxygenated blood , now returns in blood vessels back to the heart .

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86
Q

circulatory system of fish (6)

A

so blood , only passes though the heart only once .
-as it moves around the circulatory system scientists call this a single circulatory system .

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87
Q

problem with single circulatory system ?

A

when the blood passes through two sets of narrow capillaries .
-firstly ,
-firstly , in the gills . and secondly , as it passes into the body tissues when the blood passes though capillaries’ , blood flows down and looses pressure .
-MEANING –> once ,, the blood passes though the gills , blood is moving relatively slowly .

-limiting how rapidly oxygen can be delivered to body cells .

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88
Q

circulatory system in mammals (1)

A

deoxygenated blood is pumped under high pressure from the heart to the lungs .

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89
Q

circulatory system in mammals (2)

A

in the lungs , blood passes though the narrow capillaries and oxygen diffuses from air into the blood.

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90
Q

circulatory system in mammals (3)

A

As the blood , has passed though the capillaries , it is moving slowly with lower pressure .

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91
Q

circulatory system in mammals (4)

A

however , now the oxygenated blood returns back to the heart . Pumping blood at high pressure around the body .

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92
Q

circulatory system in mammals (5)

A

as it passes though the body , blood passes through the capillaries and oxygen diffuses to the body cells .

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93
Q

circulatory system in mammals (6(

A

the low pressure , deoxygenated blood now makes it way back to the heart to be pumped again .

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94
Q

so double circualtory system , blood passes though twice

A

this makes sure the blood makes it ways to the body tissues rapidly and under high pressure .

-so a double circulatory system can carry oxygen more efficiently , than a single circulatory system .

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95
Q

what is a closed sytem ?

A

-fish and mammmals , blood is always contained in blood vessels as it travels form the heart . this is a closed ciruclaotry sytem .

-in a closed cirulatory sytem , blood can move relatively rapidly , and the amout of blood pumped to differen ooorgans can be controlled by constricting or dialiating blood vessels .

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96
Q

What is an open circulatory sytem ?

A

insects have it , insects do not contain blood .
-instead , they contain a fluid called haemolymph .
-haemolymph carries nutrients also like sugar’s but do not carry oxygens //

-haemolymph is pumped out of the insects heart and passes directly into the body cavity called haermoroel .

-moelcuels are then transferred , becween the haemolymp and body ells an d hten the haemolymph makes its way back into the heart .

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97
Q

what is key about haemolymph

A

It is not carried in Venule , so it is an example of an open circulatory system .
-as the haemolympg is not Carried in vessels and jf moves rapidly around the insect .
-Also. (!3 insect is nkg essily change or cannot of how how much is moving to different parts of its body .

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98
Q

What do arteries branch to form

A

They form narrow blood vessels called arterioles.
Arteries carry the blood to the capillaries from each organ .

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99
Q

How does molecules diffuse in the capillaries

A

-Morley les diffuse from the body cells back into the blood .
-finally . The blood then passes from capillary to blood vessels called Venules and the which carry the blood back k tk the heart .

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100
Q

What way does the arteries carry the blood ?

A

Arteries carry the blood away from the heart to the organs blood on the arteries is under high pressure .

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101
Q

What is the pulse ?

A

When the heart beats , a surge of even higher blood
Pressure is pushed down the arteries scientists call this
PULSE

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102
Q

What way does the heart beat even when the heart beats ?

A

It moved FORWARD
-cross ex goin of w typical artery
- although I should point out , that very large artistes can have a wide diameter

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103
Q

Adaptation of arteries

A

The first thing to notice is that the artery wall is relatively thick .
-l this alllsws the artery to withstand high pressure of the blood .

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104
Q

The walls of the artery consist of several layers

A

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105
Q

The outer layer of the artery EXPLAIN

A

The other layer of the artery is rich in the fibrous protein collagen .
-collagen plays a structural role in, strengthening the artery wall against the pressure of the blood .

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106
Q

Next , the artery has a layer containing smooth malice

A

When the smooth muscle contracts , the diameter of the artery narrows .
THis alllws the body to control how much blood flows to different organs .

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107
Q

Different between large and small muscles

A

Smaller arteries tend to have a greater proportion of SMOOTJ muscles than larger ateries .
-that js bevause smaller attire is okay a great role in controlling blood pressure

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108
Q

Next layer w shave is elastic fibres

A

Elastin fibres contain the protein elastin which can stretch .
/when the heart contracts a surge of high blood pressure passes down the artery .

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109
Q

-as fhe surge moves through , the elastic fibres stretch , fhen recoil , once the surge has passed .

A

Elastic recoil helps the blood moving smoothly forward , inbetween contractions of the heart .

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110
Q

What is the. Entrap. about of the artery. Called ? Lumen

A

The linen is where the blood flows through. Lumen is lined with a thin layer of endothelial cells .
- this presents a very smooth surface to reduce the friction as blood flows through .

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111
Q

What do arteries branch into ?

A

Smaller blood vessels called arterioles .

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112
Q

What is the job of the arterioles

A

The jobs of the arterioles is to deliverto to the capillaries .
-the walls of the arterioles contain the same layers as arteries . -but as you will see they differe in their relative thickness .

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113
Q

Blood pressure in arterioles

A

-the blood pressure is lower than in arteries and the effect of the pulse is weak . This means , that in arterioles the collagen - rich outer mager and the elastic kager are relatively thin compared to the arteries .

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114
Q

What about the smooth muscle layer in arterioles

A

-is
Much thicker than in arteries .
- that is because arterioles are invovled in. Contracting the amount of blood passing through the capillaries .

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115
Q

What happens when the smooth muscles on the arterioles contact

A

Blood flow through the cappillaties ir reduced .
-scientists call this vasoconstriction
/hwo ded fhe smooth muscle in the arteries relaxes .
- blood flow through the capillaries increases , scientists call this vasodilation .

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116
Q

When does vasodilation take place ?

A

Vasodilation takes place when an organ requires an in increased amount of oxygen .

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117
Q

There is an extensive network of.Capillaries in every organ ?

A

As you can see , cappilladies are extensively branched and no body cell is very far from a capillary .

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118
Q

What is a network of capillaries called ?
What happens here ?

A

It is called a capillary bed .
_the capillary hed is where substances are e change between the blood and body cells .
-for example , oxygen and glucose diffuse from the blood to the body cells .

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119
Q

How do waste products diffuse ?

A

Waste products such as carbon dioxide diffuse from the cells back to the blood .

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120
Q

What does the extensive branching of capillaries provide ?

A

It provides a massive surface area for the exchange of. Materials .
- the structure of capillaries has evolved tk maximise the rate of diffusion for molecules such as oxygen .

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121
Q

What are the walls of capillaries like in the blood vessels ?

A

They ade extremely thin walls
-in fact , the walls of the capillaries consist of a single layer of endothelial cells .

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122
Q

What is the outside membrane like of capillaries ?

A

There is a thin membrane called the basement membrane .
-consists of a single layer of cells .
-making there is a short diffusion distance between the blood and the cells near the capillary .

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123
Q

Why does the shift diffuse distance of the capillaries help ?

A

-it increases the rate of diffusion for molecules .
-between the blood and the cells for example oxygen and carbon dioxide .

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124
Q

What is the diameter of the capillary lumen like compared to. Red blood cell

A

It is only slighted higher than a red blood cell .
—this means that when red blood cells pass through the capillary , they are pressed against the capillary wall .

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125
Q

What is the effect of the red blood cells being pressed against the wall !

A

This reduces the distance for diffusion fo oxygen .
-from the red blood s tk the tissue cells .
- as the lumen of the capillaries is only slightly wider than a red blood cell .

-meaning ew e blood cells reve
Though capillaries in a single file. /

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126
Q

What does it mean as red blood cells are travelling in single file ?

A

Because of this , red blood cells
Love though the capillaries
More
Slowly than on arteries and arterioles .
-this relative movement , increases the time available for molecules to diffuse in and out of the blood S

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127
Q

Last adaptation of capillaries
-if we look at the capillaries we can see gaps between endothelial cells .

A

These gaps allow fluid to pass out of the blood and scientists flak this tissue fluid .
- tissue fluid ? Bathes the cells providing essential molecules such as glucose and amino acids .

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128
Q

What do the gals in the capillary wall do ?

A

Allow white blood cells to leave the blood steam .

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129
Q

Where does the blood goe after it passes though the capillary ?

A

It makes its way though very small veins called the venules .

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130
Q

What do venules connect into . S

A

Venules connect into larger veins .
- these veins carry deoxygenated blood to the venavava where it passes into the heart .

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131
Q

How does blood in the Venules travel ?

A

Unlike arteries the blood in the Venules and veins flow under flow pressure and it is not travelling in pulses .
-this means that the structure of the veins is different to the arteries .

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132
Q

Why do veins have thinner s than arteries ?

A

This is because the walls of the veins do not need to withstand high blood pressure.

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133
Q

Why do veins have a larger lumen ?

A

To carry a greater volume of blood compared to the arteries .
- the smooth muscle layer and the elastic.are thinner in veins compared to the arteries .

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134
Q

Rememebr , the blood on veins does not travel in pulses , so there is no elastic. Recoil .

A

However , just like arteries. (!: lumen of the veins has an internal lining of endothelial cells . The smooth surfaces reduces the friction between the old and the walls of the veins .

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135
Q

Another important adaptation of grind er nerd yo learning that veins contain valves .

A

These valves keep the blood flowing in the forward direction.
- rememebr , the blood vessels are moving back to the heart .
Meaning blood may well be moving against gravity especially in legs and arms

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136
Q

Problem of blood in the veins ?

A

It is travelling slowly and under low pressure q

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137
Q

Quesfion ? What makes blood in the veins move back to the heart

A

Many veins are found lying between the skeletal muscles such as the large muscle of the arms and legs .
- when these muscles contract e.g during normal movement , they stayed: between the veins lying between them .

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138
Q

Blood flowing back to the heart part two

A

As we have seen xx veins have relatively thin walls . So when they squeeze they change shape .
This squeezing forces the blood along . If the blood moves forward then the valves. Remain open XD s
/however if the blood starts to move backwards fhen then the valves shut

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139
Q

The combined egg feed kd the muscles Darryl’s and the grind Ed erll Ed the action of the valves

A

Helps to keep the blood moving towards the heart .

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140
Q

What are the two main components of blood

A

Cells —> red blood cells which transport oxygen and white blood cells which play a role in the immunity .
- blood cells are suspended and cell fragments platelets are in a water solution invovled in blood clotting called blood plasma .

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141
Q

What does blood plasma contain

A

Blood plasma contains a range of dissolved molecules such as glucose and amino acids and ions such as sodium ions xx

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142
Q
  • blood plasma also cotnains dissolved oxygen which ?
A

Blood plasma also contains contains dissolved oxygen which doffusss out of the red blood cells. .
- another very important of blood plasma are proteins such as Albanian scientists refer to these as plasma proteins. .

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143
Q

What does the fluid do in the capillaries ?

A

The fluid passes out of the blood and bathed the tissue cells .
- scientists call it tissue fluid .

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144
Q

What does tissue fluid do ?

A

Tissue fluid leaves the bloood at the part of the capillary which is near the artery .
/ tissue fluid transfers molecules such as oxygen and tissue cells .

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145
Q

What do waste meocluels from tissue cells do ?

A

Did exmsd co2 pass into the tissue fluid
- the tissue fluid then truths bsck I my o the bloodstream. Af parts of the capillary which are near the vein ,

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146
Q

Stage one of how tissue fluids move on and out of the blood (1)

A

Tissue fluid is forced out of the blood at the arterial end of the blood capillary . And returns back to the blood at the venous end of the blood capillary ,

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147
Q

In order to understand the tissue fluid process we need to look at two competing factors

A

-. These are calllrd hydrostatic pressure and on proof oressure
/ structural end of capillary whrte tisdru fluid it reached - at the end of the capillary , the blood ha: .

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148
Q

end of the capillary the blood has just passed into an arteriole

A

-because of this , the blood at the arterial and of the capillary is still under relatively high pressure ,

-scientists call this hydrostatic pressure

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149
Q

what does hydrostatic pressure do ?

A

hydrostatic pressure tends to force fluid out of the blood into the tissue .
-remember , in blood plasma , got plasma proteins like abeli .

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150
Q

what do plasma proteins do ?

A

-plasma proteins are hydrophilic so they try to lower the water potential , of the blood plasma .

-because the plasma proteins , there is a tendency for water to move back into the blood by osmosis .
-scientists call this oncotic pressure .

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151
Q

what is the hydrostatic pressure like at the arterial end ?

A

the hydrostatic pressure is greater than the oncotic pressure .
-this means tissue fluid is forced out of the capillary through the gaps between the endothelial cells .
-scientists call this process ultrafiltration .

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152
Q

do proteins and blood plasma leave ?

A

no , they are too large so they remain in the blood plasma .

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153
Q

What is the hydrostatic pressure like ,a t the venous end ?

A

The hydrostatic pressure is much lower , as a large amount of water has left the blood .

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154
Q

how is the oncotic pressure like at the venous end ?

A

the oncotic pressure is still high due to the plasma proteins in the blood plasma .
- so , because of this ,a t the venous end , the hydrostatic pressure is less than the oncotic pressure . Causing , water to move back to the blood by osmosis .

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155
Q

Around 90% of the tissue fluid is reabsorbed back into the blood .
what happens to the remaining ten percent .

A

the remaining ten percent of the tissue fluid drains into a series of blind-ended valves called lymph capillaries .

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156
Q

What do lymph capillaries do ?

A

Lymph capillaries connect into large lymph vessels forming the lymphatic system .
-the lymphatic fluid moves along to the lymph vessels are squeezed by nearby skeletal muscles .

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157
Q

There are also valves in the lymph valves , why ?

A

valves into he lymph help to keep the lymph fluid .

-eventually , the lymph fluid returns to the blood stream via blood vessels under the collar bone .
-the lymphatic system also plays a role in immunity .

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158
Q

what is the activity of insects ?

A

insects can be extremely active organisms with a very high oxygen demand . For examples , during flight .

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159
Q

What is key about the gas exchange in insects ?

A

gas exchange systems in insects have evolved to provide oxygen directly to cells .
-although insects do have a specialised transport system , this only tansfers nutrients not oxygen .

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160
Q

What are insects covered in to aid gas exchange ?

A

insects are covered with a protective exoskeleton , made from the polysaccharide chitin .

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161
Q

-gases such as oxygen and carbon dioxide cannot easily pass through the exoskeleton , so what does the exoskeleton have to aid this ?

A

-On the surface of the exoskeleton , we have small openings called spiracles .
-Spiracles allow gases such as oxygen and carbon dioxide to diffuse into the body of the insect .

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162
Q

what do spiracles lead to ?

A

spiracles can lead into a network of tubes called trachea .
-The trachea are relatively wide tubes with a diameter of 1 mm .
-trachea extends down and along an insects body .

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163
Q

what are the walls of the trachea reinforced with ?

A

they are reinforced with spirals of chitin .

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164
Q

what does the chitin do in the trachea ?

A

-the chitin prevents the trachea from collapsing example when an insect moves .
-extending from the trachea are very fine tubes called tracheoles .

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165
Q

give one adaptation of tracheoles

A

tracheoles have a diameter of around 1mm or less / So in fact , they are much mroe narrow then shown .
-each trachea is a single cell that has extendfed to forma hollow tues .

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166
Q

where do the tracheoles extend into ?

A

down in-between the insects body .

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167
Q

another adaptation of tracheoles

A

-unlike trachea , tracheoles are not supported by chitin . Because , tracheoles have such a narrow diameter and have an extremely close to cells .. there is a very short diffusion distance for gases moving in between the cells and for gases moving between he cells and the tracheoles .

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168
Q

another adaptation of tracheoles (2)

A

this allows , oxygen to diffuse rapidly from the air in the trachea , into the cells .
-the oxygen is needed for aerobic respiration which produces the gas carbon dioxide .
-the carbon dioxide can also rapidly diffuse back into the air in the tracheoles .

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169
Q

Give a third adaptation of tracheoles

A

huge number of tracheoles provide a very large surface area for gas exchange .
-this allows insects to maintain a very rapid rate of aerobic respiration (flight)
-the ends of the trachea are filled with fluid aka tracheal fluid .

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170
Q

what happens during intense activity in insects

A

cells undergo anaerobic respiration .
-anaerobic respiration produces lactic acid , lowering the water potential of cells.#

-This then causes the water in the tracheal fluid to move into the cells .
-This reduces the volume of the trachea fluid drawing air into the tracheoles.
-also means more tracheole surface is available for diffusion of carbon dioxide and oxygen

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171
Q

In many insects , gas exchange is essentially an a passive process , explain ?

A

-oxygen diffuses down the co2 gradient and from high concentrations in the external air .
-rate of diffusion decreases with distance meaning insects tend to be small .
-smaller size insects reduces distance for diffusion to take place .

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172
Q

What is the significant problem that insects face ?

A

Loss of water .
-walls of the tracheoles are moist and the ends of the tracheoles contain tracheal fluid .
-meaning water vapour can diffuse out of the insect via the spiracles .

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173
Q

however , what is the spiracles surrounded

A

each spiracle is surrounded by a muscular sphiniser, this means that insects can reduce water loss by closing their spiracles .
(e.g insects increase oxygen requirement )

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174
Q

some insects have evolved to gas exchange

A

if we look at insects we can see we have three main body segments .

-head
-thorax
-abdomen .
-some insects can also contract muscles to change the volume of the thorax and the abdomen

-causing pressure changes in the trachea and tracheoles , pushing air in and out this bulk movement of air is called mass transports .

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175
Q

in some insects , the trachea contain expanding sections called air sacs . Explain what the air sacs do ?

A

changes in the volume of the thorax and the abdomen can squeeze the air sac causing air to move from the airspaces into the tracheoles .

-insects can also use the oxygen in airsacs during … when spiracles have been closed for water conservation .

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176
Q

what do larger organisms have compared to smaller organisms ? 1

A

-larger organisms have a much lower surface area to volume ration with the vast majority of cells a large distancer form he surface of the organisms .

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177
Q

what do larger organisms have compared to smaller organisms ? 2

A

also larger organisms often are very active and have a high demand for aerobic respiration .
-meaning larger organisms cannot rely on diffusion alone for the diffusion if exchange in materials .

178
Q

we have already seen how insects fish and humans have specialised gas exchange systems.

however , what is different in humans and fish ?

A

gases dissolve in blood , which acts as a transport system .
-The blood , then moves around the circulatory system . transferring gases between the cells and gas exchange system .

179
Q

What other essential molecules does blood transfer ?

A

other essential molecules include glucose and amino acids .
-when molecules are carried in a transport medium such as blood through a circulatory system scientists call this mass transport .

180
Q

stage one of circulatory system of fish

A

deoxygenated blood is pumped by the heart through blood vessels to gills .

181
Q

stage two of the circulatory system of fish

A
  • in the gills , blood passes though narrow blood vessels called capillaries.
    -Oxygen diffuses from the water into the blood .
182
Q

stage three of the circulatory system of fish

A

the oxygenated blood now passes from the gills through the blood vessels to the body tissues .

183
Q

stage four of the circulatory system of fish

A

when it reaches the body tissues , the body again passes through narrow capillaries , where oxygen diffuses from the blood to the cells that need it .

184
Q

stage five of the circulatory system of fish

A

finally , the deoxygenated blood ,only returns in blood vessels back to the heart .

-so blood only passes , through the heart once , as i moves around the circulatory system , scientists call this a single circulatory system .

185
Q

what is the problem with the circulatory system of fish ?

A

when blood leaves the heart , the pressure of the blood is high , and the blood is moving rapidly .

-however blood then passes through narrow capillaries where oxygen diffuses from the blood to the cells that need it .

186
Q

stage six of the circulatory of fish

A

finally , the deoxygenated blood now returns in blood vessels back to the heart .-so blood only passes through the heart once .
-as it moves around the circulatory system ,scientist call this a single circulatory system :)

187
Q

problem with single circulatory system ?

A

when the blood leaves the heat , the pressure of the blood is high , and this means blood is moving rapidly ,..
-however , blood then passes through two sets of narrow capillaries

188
Q

problem with single circulatory system ? (2)

A

firstly in the gills and secondly as it passes through the body tissue when the blood passes through the capillaries , blood flows down and looses pressure .
-MEANING , once the blood passes through the gills it is moving relatively slowly .
-This limits , how rapidly oxygen can be delivered to the body cells

189
Q

circulatory system in mammals (1)

A

deoxygenated blood is pumped under high pressures from the heart to the lungs .

190
Q

circulatory system in mammals (2)

A

in the lungs , blood passes through narrow capillaries and oxygen diffuses from the air into the blood .

191
Q

circulatory system in mammals (3)

A

as the blood , has passed through the capillaries is its moving at a relatively lower pressure .

192
Q

circulatory system in mammals (4)

A

however , now oxygenated blood returns back to the heart , pumping blood at high pressure around the body .

193
Q

circulatory system in mammals (5)

A

as it passes through the body , blood passes through the capillaries and oxygen diffuses to the body cells .

194
Q

circulatory system in mammals (6)

A

the low pressure , deoxygenated blood molecules it way , back to the heart and to be pumped again .

195
Q

what happens in a double circulatory system ?

A

in a double circulatory system , blood passes through the heart twice .
-this ensures blood moves to the bodyt issues rapidly under high pressure .

-so a double circulatory system can something oxygen more efficiently than a single circulatory system .

196
Q

where is blood contained in fish and mammals ?

A

blood is always contained in blood vessels as it travels to and from the heart .
-scientists this is a closed circulatory system .

197
Q

what is a closed system ?

A

in a closed circulatory system , blood can move relatively rapidly , and the amount of blood passing to different organs can be controlled constricted by dilating blood vessels .

198
Q

WHat do insects have?

A

Insects have an open circulatory system . Insects do not contain blood .

199
Q

What do insects have instead of blood ?

A

Instead ,they contain a fluid called haemolymphs .
-Haemolymph carried nutrients aka sugars but does not carry oxygen .

200
Q

Where is haemolymph situated , how is it transported ?

A

haemolymph is pumped out of the insect’s heart and passes directly into the body cavity is called haemocoel .

201
Q

how is haemolymph transported ?

A

molecules are then transferred between the haemolymph and body cells and them haemolymph makes its way back into the heart .

-key ; haemolymph is not carried in vessels so it si an exmpa,e of an open circulatory system .

202
Q

speed of haemolymph

A

As the haemolpyh is not carried in vessels it does not move rapidly around the isnect .

-also the insect , does not easily change conc of hameolpyh moving to different parts of the body .

203
Q

What to arteries branch to form ?

A

arterioles

204
Q

what is the function of arterioles

A

arterioles carry the blood to the capillaries in each organism .

205
Q

how do molecules diffuse in the capillaries ?

A

In the capillaries , molecules diffuse from the blood to the cells example glucose and oxygen
-other molecules diffuse from the body back to the heart .

206
Q

what direction do arteries carry the blood ?

A

away from the heart to the organs .
-blood in the arteries is under high pressure .
-when the heart beats , a surge even high blood pressure is pushed down in the arteries calls this pulse .

207
Q

blood is always moving forwards between heart beats for arteries .

A

208
Q

cross section of arteries
-how thickkk is she

A

4-10mm is the cross section of a typical artery .
-however , some arteries do have a wide diameter .

209
Q

what is the first thing to notice about artery walls ?

A

artery walls are relatively thick .
-this allows the artery to withstand the high pressures of the blood .
-the walls of the arteries consist of several layers .

210
Q

what is the outer layer of the artery like ?
-what does it have that helps w structure ?

A

the outer layer is rich in fibrous protein collagen . Which we looked at previously .
-Collagen plays a role structurally , strengthening the artery wall against the pressure of the blood .

211
Q

explain the next layer of the artery that contains smooth muscle , not like isaacs bum ?

A

-when the smooth muscle contracts when isaac needs to take a dump , the diameter of the artery narrows .
-this allows body to control how much blood flows to different organs ,
like isaac controlling his plops .

212
Q

what do smaller arteries have compared to larger arteries and why ?

A

smaller arteries tend to have a GREATER proportion of smooth muscles than larger arteries .
-That’s because smaller arteries play a great role in controlling bloodflows .

213
Q

next layer we have in arteries is elastic fibres , what do they do part one

A

elastic fibres contain the protein elastin , which can stretch .
-when the heart contains a surge of high pressure , passes down the artery .

214
Q

elastic fibres part two

A

-as the surge moves through , the elastic fibres stretch , then recoi . one of the surges have passed .
-elastic recoil , helps the blood move smoothly forward , inbetween contractions of the heart .

215
Q

what is the central cavity of the artery called , what happens here ?

A

the central cavity of the artery is called the lumen .
-the lumen is where the blood flows though lumen is lined with a thin layer of endothelial cells.
-this presents a very smooth surface to reduce friction as blood flows throuh .

216
Q

what do arteries branch off into ? what do they do

A

arteries branch into smaller arterioles .
-arteries branch is to deliver blood to the capillaries .
-the wall of the arterioles contain the same layer as arteries .
-but they differ in their relative thickness

217
Q

what is the blood pressure like in the arterioles ?
-What is the effect of this on the pulse, what does this mean ?

A

;-The blood pressure is lower than in the arteries .
-the effect of this is that the pulse is weaker .

218
Q

What does a weaker pulse mean in the arterioles ?

A

This means that in the arterioles the collagen - rich outer layer .
-rich outER LAYER and the elastic layer are relatively thin compared to the cells .

219
Q

what is the thickness of the connective tissue and smooth muscle layer like and why ?

A

it is relatively thicker in arterioles compared to arteries .
-That’s because arterioles are involved in controlling the amount of blood passing through the capillaries .

220
Q

What happens when the smooth muscle in the arteries contract ?

A

-Blood flows through the capillaries is reduced .
-scientists call this vasoconstriction .

221
Q

what happens when the smooth muscles in the arteries relax ?

A

-blood flow increases through the capillaries scientists call this vasodilation .

222
Q

when does vasodilation happen ?

A

takes place when an organ requires an increased amount of oxygen .

223
Q

extensive networks of capillaries adaptations

A

capillaries are extensively broad and no body cell is very far from a capillary .
-a network of capillaries is called a capillary bed .

224
Q

What happens in the capillary beds ?

A

-The capillary beds are where substances are exchanged between the blood and body cells .
-for example , oxygen and glucose diffuse from the blood into the body cells .
-while , waste products such as carbon dioxide diffuse from the cells back into the blood .

225
Q

what does the extensive branching of capillaries provide ?
-give the adaptation

A

-the extensive branching provides a massive surface area for the exchange of materials .
-the structure of capillaries has evolved to maximise the rate of diffusion for molecules such as oxygen .

226
Q

what are the thickness of the walls of the capillaries like ?

A

capillaries have extremely thin walls.
-the walls consists of single endothelial cells .

227
Q

what is on the outside of the capillary walls ?

A

the outside of the capillary walls , there is a thin membrane called the basement membrane .

228
Q

what is the advantage of thin walls for capillaries ?

A

-as the capillary wall consists of a single layer of cells , this means that there is a very short diffusion distance between the blood and the cells near the capillary /
-this short distance increases the rate of diffusion of molecules between the blood and the cells for example oxygen and carbon dioxide .

229
Q

what is the diameter of the lumen of the capillary like , and what does this mean ?

A

-the diameter of the capillary lumen is only slightly bigger than red blood cells .
-this means that when red blood cells pass through the capillary , they are pressed against the capillary wall .

230
Q

adaptations of the lumen of the capillary part two

A

-this reduces the distance for the diffusion for the distance of diffusion of oxygen .,
-from the blood cells to the tissue cells .

231
Q

how do blood cells travel through the capillary ?

A

-this means red blood cells travel through capillaries in single file .
-because of this , red blood cells move through the capillaries more slowly in arteries than in arterioles .
-This relatively slow movement , increases the time available for molecules to diffuse in and out of the b lood /

232
Q

what is the final adaptation of capillaries

A

-if we look at the capillary wall , we can see small gaps between the endothelial cells .
-these gaps allow fluid to pass out of the blood , scientists call this tissue fluid .

233
Q

What does tissue fluid do ?

A

tissue fluid , bathes the cells , providing essential molecules such as glucose and amino acids .

234
Q

What do gaps in the capillary wall do ?

A

the gaps in the capillary wall , also allow white blood cells to leave the bloodstream

235
Q

once blood passes through the capillaries , where does it go ?

A

-It makes its way through very small veins called venules .

236
Q

where do veins connect to ?

A

venules , then connect into larger veins .
-these veins carry deoxygenated blood into the vena cava , where it passes into the heart .

237
Q

what is the pressure of the blood like in the veins and venules .

A

it is under low pressure , and it is not travelling in pulses .
-this means that the structure of the veins is different to arteries .

238
Q

why do veins have thinner walls ?

A

veins have thinner walls than arteries as the walls of the veins do not need to withstand high blood pressure .

239
Q

what is the lumen of the veins like and why ?

A

veins have a larger lumen and carry a greater volume of blood compared to arteries .

240
Q

what are the walls like in veins ? (endothelial etc )

A

the smooth muscle layer and the elastic layer are thinner in veins compared to the arteries .
-As the blood in the veins does not travel in pulses , so there is no elastic recoil .

241
Q

What is the internal lining of the lumen like ?

A

the internal lining of endothelial cells .
-the smooth surface reduces friction between the blood and the walls of the vein .

242
Q

veins contain valves , explain why

A

-these valves keep the blood flowing in the forward direction .
-remember , blood in veins is moving back to the heart , meaning blood may well be moving against gravity example in the legs and arms .

243
Q

problem , blood is travelling in veins at a relatively low pressure .
-question what makes blood in veins move back to the heart ?

A

-many veins are found lying between skeletal muscles , such as the large muscles in arms and legs .
-when the muscles contract , during movement , they squeeze between he veins lying between them .

244
Q

problem , blood is travelling in veins at a relatively low pressure .
-question what makes blood in veins move back to the heart ? part two

A

as we have seen , veins have relatively thin walls , so when they squeeze , they change shape .

-this squeezing , forces the blood along .if the blood moves forward then the valves remain open .
-however if the blood starts to move backward then the valves shut .

-tis combined effect of the muscles squeezing and the veins , as well as the action of the valves helps the blood move towards heart ,

245
Q

what is another factor that makes blood in the veins move back to the heart ?

A

when we inhale , the pressure of the chest cavity decreases .
-this decrease in pressure , helps t he blood in the chest veins to move forwards towards the heart .

246
Q

blood has two components , what is the first component ?

A

cells , red blood cells which transport oxygen and while blood cells play a role in immunity , blood cells are suspended and cell fragments and platelets in watery solutions , are involved in blood clotting , scientist call this blood plasma .

247
Q

What doe

A
248
Q

What does blood plasma contain ?

A

it contains a range of dissolved molecules such as glucose , amino acids and ions such as sodium ion na+ .

249
Q

what else does blood plasma contain ?

A

blood plasma also contains dissolved oxygen which diffuses out of the red blood cells .
-another very important part of blood plasma are proteins such as albumin .
-scientists refer to these as plasma proteins .

250
Q

what is the fluid like in the capillaries ?

A

fluid is pushed out of the blood and bathes the tissue cells .
-scientists call this tissue cells .

251
Q

what do waste products do in the tissue cells ?

A

waste molecules from the tissue cells such as co2 , pass into the tissue fluid .
-the tissue fluid then returns back into the blood stream and passes out of the capillary which is near the vein .

252
Q

how does tissue fluid move in and out of the blood part one ?

A

-tissue fluid is forced out of the blood at the arterial end of the blood capillary and reutrn back to the blood at the venous end of the capillary /

253
Q

in order to understand how tissue fluid is moving need to understand two competing factors , what are they ?

A

hydrostatic and oncotic pressure .

254
Q

what happens at the arterial end of the capillary ?

A

blood has just passes through an arteriole .
-because of this , the blood at the arterial end of the capillary , is still under relatively high pressure .
-scientists call this hydrostatic pressure ?

255
Q

what way does hydrostatic pressure push blood ?

A

hydrostatic pressure tends to force fluid out of the blood and into the tissue .
-remember in blood plasma , got plasma proteins as alb thatthing .

256
Q

what do plasma proteins do in relation to hydrostatic pressure.

A

plasma proteins are hydrophilic so they lower the water potential of the blood plasma .
- because of this , the plasma proteins , there is a tendency for the water to move back into the blood by osmosis .
-scientists call this oncotic pressure .

257
Q

what is the blood pressure like at the arterial end of the capillary ?

A

the hydrostatic pressure is greater than the oncotic pressure .
-this means that tissue fluid is forced out of the capillary through the gaps between the endothelial cells . scientist call this process ultrafilitiriatiom /

258
Q

does blood cells and plasma proteins leave the blood ?

A

no ,t hey are too big

259
Q

what happens at the venous end of the capillary ?

A

hydrostatic pressure is much lower as a large amount of water has left the blood .
-however , oncotic pressure is still high due to plasma proteins in the blood plasma , because of this , at the venous end , the hydrostatic pressure is less than the oncotic pressure .
-causing water to move in by osmosis into the blood

260
Q

how much of the tissue fluid is reabsorbed back into the blood

A

around 90 %

261
Q

what happens to the remaining ten percent of tissue fluid ?

A

it drains into a series of blind-ended vessels called lymph cappillaries .

262
Q

what happens in lymph capillaries

A

-lymph capillaries connect into large lymph vessels forming the lymphatic system .
-lymphatic fluid something when lymph vessels are squeezed by nearby skeletal muscles .

262
Q

what do valves in the lymph valves do ?

A

they gelp to keep the lymph fluid move forward .
-eventually , the lymph fluid returns to the blood system via blood vessels under the …

263
Q

where else does the lymphatic system play a crucial role ?

A

in immunity .

264
Q

what are red blood cells also known as and what do they do ?

A

erythrocytes , and they transport oxygen .

265
Q

adaptation one of erythrocytes ?

A

they have a biconcave structure giving them an increased surface area to volume ration , allowing oxygen to diffuse in and out rapidly .

266
Q

second adaptation of erythrocytes

A

each erythrocyte contains around 300 million molecules of the oxygen carrying protein haemoglobin .

267
Q

third adaptation of erythrocytes

A

although erythrocytes initially have a nucleus , this is lost before the erythrocytes enter circulation .
-absence of this means more erythrocytes volume is available to carry haemoglobin .

268
Q

describe the structure of haemoglobin

A

4 polypeptide chains .
-each binds to a prosthetic group haem
-iron ion fe2+
-so it is an example of a conjugated protein .

269
Q

check sheet for equation , and explain it
-is it a reversible reaction ? explain the effect of this

A

each of the fe2+ in the haem molecule can combine with one molecule of oxygen l.
-as there are four haem groups in each haemoglobin molecule .
–as it is a reversible reaction , oxyhaemoglobin can also release the oxygen when required .

270
Q

how can we measure the amount of oxygen that combines with haemoglobin ?
what does this thing show

A

-oxygen dissociation curve .
-on the y axis shows the percentage saturation of haemoglobin with oxygen . x axis is partial pressure of oxygen .

-as oxygen is a gas wee do not say it is the CONC of oxygen

271
Q

what shape does the graph have ?

A

s shape - sigmoid curve

272
Q

what does the graph tell us about haemoglobin ?

A

-sample of haemoglobin , as we increase the kpa , the percentage saturation of haemoglobin increase restively slowly .

273
Q

what does star one of the oxygen dissociation curve .show

A

at around 4 kpa , 25% saturation , each haemoglobin molecule
-bound to ne oxygen molecule .

-meaning low partial pressure of oxygen has haemoglobin has a low AFFINITY for oxygen .

274
Q

what does affinity mean

A

how strongly the oxygen binds to the haemoglobin

275
Q

what happens if one oxygen molecule binds ?

A

the affinity of haemoglobin of oxygen increases , and becomes much easier to bind to further oxygen molecules .

276
Q

what will happen if we increase the partial pressure of oxygen to around 7 KPA

A

WEACHIEVE 75% SATURATION , AKA 2 more oxygen molecules have bound .

277
Q

can explai8n the 75% saturation by looking at the structure of haemoglobin molecule

A

remember , haem contians 4 polypeptides .
-each polypeptide contains 4 haem groups whhich can bind to oxygen .

-if there is NO oxygen , then rthe haem graph will show low affinity for oxygen moelcules .

278
Q

what does a low affinity for oxygen mean ?

A

this means it takes a relatively large partial pressure for oxygen , so the first oxygen molecule can bind to a haem group .

-however , when one oxygen binds , the quaternary structure of the haemoglobin molecule changes .

-this now increases the affinity of the haem groups for oxygen .

279
Q

so binding more oxygen molecules …

A

only ,,, protein haemoglobin .

280
Q

when does partial pressure of oxygen decrease ?

A

-as tissue cells take up oxygen for aerboic respiration .

281
Q

-at a certain partial pressure , an average of oxygen molecule can now what , and what does this mean ?

A

one oxygen molecule can now unload each haemoglobin molecule .
-when one oxygen molecule unloads , this changes the quaternary structure of the haemoglobin and the effect of this is to reduce the affinity of the haem groups for oxygen .

282
Q

what happens to the pressure of the blood , if the blood passes though a very active site for example muscles

A

then the partial pressure of oxygen will fall even further .
-as the haemoglobin has a reduced affinity for oxygen it is now more easy for oxygen molecules to unload .

283
Q

another factor that needs to be considered is the partial pressure of co2 , and the effect it has on the oxygen dissociation curve .

A

-highlighted line in yellow , shows the carbon dioxide .
-shows haemoglobin when the co2 , is relatively low , partial pressure of c02 increased , in muscle tissue .

284
Q

what way does co2 , shift the curve ?

A

it shifts the oxygen dissociation curve to the right .
-what this means is that co2 k,, causes the oxygen affinity of haemoglobin o decrease , scientist call this the bohr effect .

285
Q

explain the bohr effect using the graph

A

if the partial pressure of co2 is low , then the haemoglobin is 75% saturated at a partial pressure of o2 at 7kpa ;/

286
Q

what is the partial pressure of oxygen , when partial pressure of co2 is high ?

A

then the haemoglobin is only 25 % saturated at the same partial pressure of 02 ,a s before .
-so the effect of co2 , is to reduce the affinity of haemoglobin for oxygen .

287
Q

start with this cardd

  • a relatively small increase in the oxygen partial pressure , what do scientist call this ?
A

positive cooperativity .

288
Q

why does the fourth haem group , only bind to oxygen at a fairly high partial pressure ?

A

that is because , 3 of the 4 haem groups have already been filled .
-so the chances of an oxygen molecule colliding with a 4th haem gorop is relatively low .

289
Q

where is the partial pressure of oxygen high , and what happens here ?

A

-in the alveoli , the partial pressure of oxygen is high and the haemoglobin , in red blood cells is around 97% saturated .

-

290
Q

-however m at a certain point , one oxygen molecule now unloads from the haemoglobin molecule .
-what does this unloading do to the structure .

A

-however m at a certain point , one oxygen molecule now unloads from the haemoglobin molecule .
-the effect of this is to decrease oxygen affinityo f the remaining haem groups .

291
Q

what will happen if the red blood cells moves into more active tissue ?

A

then the oxygen partial pressure will be even lower and two more oxygen molecules will rapidly unload from the haemoglobin molecule .

292
Q

what will happen when the final oxygen molecule unloads ?

A

-the partial pressure of oxygen has to be very low .
-this is unlikely to happen under normal conditions but it could take place in very active tissue example muscle tissue during intense exercise .

293
Q

if we plot the percentage of haemoglobin with oxygen against the partial pressure , what do we get ?

A

-oxygen dissociation curve .
-aka affinity of haemoglobin or oxygen , how strongly haemoglobin bind to oxygen depends on the partial pressure of oxygen .

294
Q

check sheet for rest .

A

295
Q

what is the first important effect co2 has

A

haemoglobin , has a higher affinity for oxygen , in conditions where the partial pressure of co2 is low , in the left hand side .

296
Q

In what places will oxygen and carbon dioxide be high ?

A

-in he lungs , haemoglobin has a high level of oxygen saturation .
-however , partial pressure of co2 , will be high when undergoing aerobic respiration , in muscle tissue .

297
Q

in blood , what can carbon dioxide form ?

A

it can form the , the acidic molecule carbonic acid .
-carbonic acid , released hydrogen ions h+ , the h+ combines with haemoglobin ,, causing the quaternary structure of haemoglobin to change .

-therefore , haemoglobin , has a lower affinity for oxygen , causing haemoglobin o unload oxygen more easily .

298
Q

how is the circulatory system of a foetus linked with maternal circulatory system ?

A

in the placenta , the fetal blood and the maternal blood pass closely to each other but they do not mix .

299
Q

what does the maternal blood have compared to the foetal blood ?

A

-the maternal blood has a high level of oxygen than foetal blood
-this causes , oxygen to diffuse across the placenta and into the foetal blood .
-to make oxygen transfer more efficiently , foetal haemoglobin is different to adult haemoglobin .

300
Q

look at the oxygen dissociation curve difference between foetus and an adult . What does it show ?

A

-oxygen dissociation curve has shifted to the left compared to adult haemoglobin .
-meaning foetal haemoglobin has a higher affinity for oxygen , then adult haemoglobinn .

301
Q

what does this higher affinity for oxygen do ?

A

it increases , the oxygen transfer across the placenta from the maternal haemoglobin to the foetal haemoglobin .

302
Q

notice that oxygen affinity of fetal haemoglobin is only slightly greater than in adult haemoglobin , why is this ?

A

-if the foetal haemoglobin had a very high oxygen affinity , this could prevent it from unlading oxygen the foetal tissues .

-so the oxygen affinity is only slightly greater than in adult .

303
Q

however , in foetal haemoglobin , to of the polypeptide changes are different than in adult haemoglobin .

A

due to this difference in gene , explain the foetus compared to adult .
-this difference , in polypeptide chains in the fetal haemoglobin means it has a higher oxygen affunity .

304
Q

what is the last factor to consider about foetal blood ?

A

carbon dioxide from the foetus , dissolve’s into the maternal blood . this carbon dioxide lowers the oxygen affinity for maternal haemoglobin .

-combined with a higher oxygen affinity of foetal haemoglobin , this makes oxygen transfer from maternal blood to foetal blood extremely efficient .

305
Q

all cells produce co2 , during what and what happens to the co2 ?

A

co2 , can be added to respiring tissues in the lungs where it is broken down .

306
Q

what is one way carbon dioxide can be transported in the blood ?

A

around 5% of the carbondioxide dissolves directly in the blood plasma

307
Q

what is another way carbon dioxide can be transported in the blood

A

around 20 % forms a compound with haemoglobin molecules in the red blood cells .
-remember , haemoglobin contains 4 polypeptide chain .
-in each of polypeptides the one amino aid has a free amino group .
-each of these amino groups can react with a molecule of co2 , so one molecule of haemoglobin can react with 4 molecules of co2 .

308
Q

look at the reversible reaction , when blood passes through respiring tissue
-how does co2 , get broken down in this reaction ?

A

the lack of carbon dioxide is high and Carboxyhaemoglobin , forms .

-however , in the lungs , the level of carbon dioxide is low and the carboaminohaemoglobin breaks down releasing co2 .

309
Q

now we have seen how around 25 & of the co2 is in the blood .
-how is the remaining 75 % transported ?

A

as hydrogen carbonate ion sin the blood plasma .

310
Q

explain the next reversible reaction with carbon dioxide and water

A

-as you can se , this is a reversible reaction , this reaction usually takes place slowly , however , the red blood cells contain an enzyme which speed up the reaction .

311
Q

what is the enzyme called , and what does it do ?

A

carbonic anhydrase .
-when co2 , diffuses into red blood cells it rapidly . forms carbonic acid .
-by cobverting co2 k into carbonic acid .
-this ensures the level of c02 , in red blood cells is low .

312
Q

what does a low concentration of co2 in red bloood cells mean ?

A
  • meaning there is a steep concentration gradient for co2 .
    -due to the steep concentration gradient , there is a high rate of diffusion of co2 , inot the blood cells .
313
Q

once the carbonic acid is formed , what does it dissocisate into ?

A

-hydrogen ions and hydrogen carbonate ion .

314
Q

what happens to the hydrogen carbonate ion ?

A

-the hydrogen carbonate ion now diffuses out of the red blood cells into the blood plasma .

315
Q

what is the problem with the hydrogen carbonate ion ? and how do we prevent this

A

-hydrogen carbonate ion has a negative charge .
-when the hydrogen carbonate ion now diffuses out of the red blood cell this creates a charge something .

316
Q

-what do we do to pevent the charge for hydrogen carbonate tion ?

A

to prevent this hdyrogen carbonate ion diffuses out of red blood cell .
-negative chlorate ion diffused out of he red blood cell , the chll prvents the charge imablance in red blood cell .

317
Q

we also release hydrogen ion , what does that do to the blood ?

A

-hydrogen ion , causes the ph of the blood to falls .

-to prevent htis , haemoglobin binds to thehydrogen ions aso haemoglobina cts as buffer we call it lactic acid .

318
Q

-when the level of of carbon dioxide is high , for example in respiring tissue , what happens ?

A

-the carbon dioxide forms carbonic acid and then the hydrogen carbonate ions .

319
Q

however mw hen the level of carbon dioxide is low , for example in the lungs what happens ?

A

-in this case , the level of carbon dioxide is low , so hydrogen carbonate ions diffuse back into the red blood cells in exchange for chloride ions .
-the hydrogen carbonate ions then combine with hydrogen ions to reform carbonic acid .

320
Q

-then when is carbonic acid broken down by

A

carbonic anhydrase , forming carbon dioxide .
-carbon dioxide diffuses out of the red blood cells and into the blood p0lasma .
-once in the blood plasma , the co2 , ca be exhaled from the lungs where the blood passes though the alveoli .

321
Q

once in the blood plasma , what happens to the co2

A

the co2 , can be exhaled from the lungs ,when the blood passes through the alveloi .

322
Q

how s the heart always shown ?

A

-heart is always shown as if you are facing the person .
-lhs of the heart is shown as the right of the diagram and vice versa .

323
Q

what is heart formed from

A

cardiac muscles and have two completely separate sides .

324
Q

what are the top two chambers of the heart ?

A

-top two are called atria , these have relatively thin muscular walls .

325
Q

what are the bottom two chambers of the heart ?

A

bottom two are called ventricles .
-ventricles have much thicker muscular walls than atria .

326
Q

how are the atria separated from the ventricles /

A

by the atrioventricular valves .

327
Q

what is the left and right av valve called ?

A

-called the bicupsid valve .
-the right av valve is called the trcapsid valve .

328
Q

what are the valves attached to ?

A

they are attached to tendons which ensure the valves open in the right direction .

329
Q

the right and left side of the heart are completely separated by what ,and what does it do ?

A

by a wall called the septum .
-the septum prevents any blood from passing directly between two sides of the heart .

330
Q

transport of blood part one

A

deoxygenated blood , enters the right atrium through the vena cava .
-the vena cava has two branches .

331
Q

what does the superior vena cava do ?

A

the superior vena cava brings blood from the head and upper parts of the body .

332
Q

what does the inferior vena cava do ?

A

brings blood from the lower parts of the body .

333
Q

transport of blood part two

A

the deoxygenated blood is now pumped from the right atrium to the right ventricle .
-the right ventricle now pumps the deoxygenated blood out of the heart to the lungs through the pulmonary artery /

334
Q

transport of blood part three

A

in the lungs , the blood becomes oxygenated , oxygenated blood now returns from the lungs back to the heart inthe pulmonary vein .

335
Q

transport of blood part 4

A

the pulmonary vein brings blood into the left atrium .
-blood then passes into the left ventricle which passes the blood out of a large blood vessel called the aorta .

336
Q

transport of blood part 5

A

the aorta , transfers deoxygenated blood to all the other parts of thebodt including the heart .

337
Q

what is the right side of the heart like compared to the left ?

A

you can see that the left ventricle is a thicker muscular wall than the right ventricle .
-that is because , the left ventricles pump blood around the whole body .
-whereas the right ventricles only pump blood to the lungs

338
Q

what parts contain valves ?

A

the pulmonary artery and the aorta

339
Q

what are the coronary arteries ?

A

-blood vessels that directly branch from the aorta .
-aka - coronary artery , this supplies the heart muscle with oxygen and nutrients .

340
Q

how is the heart beat initiated ?

A

the heart beat is initiated from within the heart itself .
-aka ,the heart does not need an external signal to beat .
-as the heart triggers its own beat , scientists say its myogenic .

341
Q

where is the pacemaker ?

A

pacemarker is in the right astrium
-sinatrial node san aka pacemaker .

342
Q

how does a pacemaker work ?

A
  • the cells in the san , depolarise , they become electrically excited .
    -this triggers a wave of electrical excitation to spread across the atria ,causing the atria to contract .
343
Q

what is the contraction of the atria called

A

the systole .

344
Q

the wave of electrical excitation , crossing the atria cannot directly pass down the ventricles , why ?

A

that is because the ventricles are separated from the atria , by a layer of non-conducting tissue .
-this layer of tissue , will not pass the electrical excitation through it .

345
Q

between the atria , there is another group of specialised cells , what are they called and what do they do ?

A

atrioventricular node - avn .
-the avn is connected to conducting fibres called parylune fibres .

346
Q

what do the parlyne fibres do ?

A

initially , the parlyne fibres are budnled together , scientits call this the b unde . -

347
Q

what do the parlyne fibred so ?

A

-run down to the apex .
-or abse of the heart and then up the walls of the ventricles .

348
Q

what do the atrioventricular valves do ?

A

they detect the elastic sxcitation passing over the atria .

-after a short delay , the avn , then transmits the electrical excitrtation down the parlyne fibred , this eletrical excitation causes the ventricles to contract .

349
Q

where do the ventricles contract ?

A

from the apex upwards .
-this ensures maximum volum eof blood is pumpd out of the ventircles .

350
Q

why is there a slight delayw hen avn triggers electrical excitation ?

A

this ensures that the ventricles contract after the atria has contracted .

351
Q

what is blood moving to the heart in what cycle ?

A

the cardiac cycle

352
Q

key word in cardiac cycle - systole , what does it mean ?

A

contracting – example atria systole , contraction of the atria .

353
Q

key word in the cardiac cycle - diastole , what does it mean ?

A

diastole means relaxing , example ventricualr diastole , relaxation of the ventricles .

354
Q

cardiac cycle stage one

A

both the atria and ventricles are in diastole , aka they are relaxed .
-blood flows into the atria via the vena cava and pulmonary vein .
-causing the pressure in the atria to rise .

355
Q

cardiac cycle stage two

A

at a certain point ,the pressure in the atria , is greater than the pressure in the ventricles , causing the atrioventricualr valves to open .
-allowing blood to flow down from the atria into the ventricles .

356
Q

cardiac cycle part three

A

now , the atria contract ,a ka atrial systole takes place .
-this pushes the remaining blood from the atria down to the ventricles .

357
Q

cardiac cycle part four

A

-after a short period of time , the ventricles contract aka they enter ventricular systole .,
-pressure in the ventricles now rise rapidly .
-because the ventricular pressure is now greater than the arterial pressure , the atrioventricular valve closes .
-

358
Q

why does the atrioventricular valve close ?

A

as this prevents any blood from moving back into the atria from the ventricles .

359
Q

cardiac cycle part five

A

the semilunar valves and in the pulmonary aorta are all open .

360
Q

cardiac cycle part six

A

blood is pumped out of the ventricles to the heart .
-you will notice when the ventricles contracted ,t he atria are relaxed.

361
Q

cardiac cycle part seven

A

finally , the ventricles relax . aka they enter ventricular diastole .
-at some point , the pressure in the ventricles falls below the pressure in the pulmonary artery and the aorta .

362
Q

cardiac cycle part 8

A

this causes , the semilunar valve to shut .
-preventing blood from flowing back into the ventricles , at this point hear is ready to enter next cardiac cycle .

363
Q

scientists have determined the blood pressure in different places of the heart during the cardiac cycle , what does the graph show ?

A

-graph applies to the left side of the heart .
-top graph shows the pressure changes taking place .
-bottom graph shows valve of left ventricle .

364
Q

reference keys

A

top graph first , shows pressure in left atrium .
black line pressure in left ventricle
blue line shows pressure ina orta - which takes blood out of the ventricle .

365
Q

(focus on black line ) –> what does star one show ?

A

at the start , the left atrium is undergoing systole .
-aka contracts , causing the pressure in the left atrium to increase .

-the atrioventricular valve is also open , so blood flows down the left ventricle causing pressure of left ventricle to increase .

366
Q

what does star two show (black line focus )

A

now the left ventricle contracts , aka enters systole , pressure in the elft ventricle massively increases .
-as the pressure in the left ventricle is now greater than in the left atrium ,t he atrioventricular valve shuts .

367
Q

what does star three show ?

A

when the pressure in the left ventricle is now greater than in the aorta , the semi-lunar valve in the aorta opens .
-blood now flows out of the left ventricle through the aorta .

368
Q

what does star four show

A

the pressure in the left ventricle now falls as the blood is leaving .

369
Q

what does star five show ?

A

at a certain point , the pressure in the left ventricle is less than in the aorta .
-now the semilunar valve in the aorta closes preventing blood from being drawn back into the ventricle .

370
Q

what hap[pens while the left ventricle is contracting ?

A

the left atrium is relaxing , (yellow line ) .
-this means the left atrium is now refilling with blood .

371
Q

focus on yellow line part two

A

the left ventricle begins to relax , causing the pressure of the left ventricle to fall .
-eventually , the pressure in the left ventricle falls bellow the pressure in the left atrium .
-at this point ,the atrioventricular valve opens and blood begins ro now move into the left ventricle form the left atrium .

372
Q

what happens as the atria and ventricles refill ?

A

the heart is ready to enter the next cardiac cycle /

373
Q

what does star six do ?

A
  • we can see , blood volume increased as it is pumped into the left ventricle where the atrium contracts .
374
Q

what does star seven show

A

when the left ventricle contracts , the blood valve falls as blood moves out through the aorta.

375
Q

what does star eight show

A

finally the blood volume increases and again , when left ventricle relaxes . blood flows down from left atrium l

376
Q

How can we analyse the electrical activity of the heart ?

A

by attaching electrodes to the surface of the skin .

377
Q

check the sheet , what does the pattern show , and what does it tell us ?

A

-the resulting trace is called an electrocardiogram / ECG
-pattern of ecg tells us what is taking place in the heart , this can be divided into three sections .

378
Q

what does the p wave show ?

A

p wave shows the contraction of the atria , aka atrial systole

379
Q

what does the qrs wave show ?

A

it shows the contraction of the ventricles aka ventricular systole .

380
Q

what does the t wave show ?

A

T wave shows the relaxation of the ventricles aka ventricular diastole .

381
Q

how does the ecg correlate with the cardiac cycle ?

A

-we can map the ecg onto the graph we saw of pressure changes during the cardiac cycle .
-can see the different stages during a heart beat .

382
Q

check the ecg , what does each division show , and how is heart rate measured ?

A

-each division shows 0.2 seconds , The heart rate is showed in beats per minute

383
Q

how do we calculate bpm ?

A

-measure the time take for one heart beat .
-to do this , measure the time between the start of the p wave and the start of the next p wave .

384
Q

Some people have a slow resting heart rate , what is this called .

A

-If the heart rate is below 60 bpm , this s called bradycardia .

385
Q

when can bradycardia happen ?

A

bradycardia can happen due to athletic training ,
-which increases the stroke volume of the heart .

386
Q

what is the bpm like in bradycardia ,and why ?

A

-as the heart pumps a greater blood volume per beat , the number of bats per minute decreases .

387
Q

why may someone develop bradycardia ?

A

some people may develop bradycardia as a result of a disease , these people may require an artificial pacemaker .

388
Q

some people have a heart rate greater than 100 bpm , what is this called ?

A

This is called tachycardia .
-tachycardia , can be caused by short term effects such as fear , panic or exercise .

389
Q

what cab long term tachycardia be caused by ?

A

problems with the sinoatrial node , or other medical problems .
-in this surgery or drugs may be required .

390
Q

what is an example of an ectopic heartbeat ?

A

an ectopic heartbeat is an extra heartbeat , that is not part of the heart’s usual rhythm .
-heart contracts again before first contraction has finished . This is then followed by a short pause , before the normal rhythm continues .

391
Q

what is the severity of an ectopic heartbeat ?

A

ectopic heartbeat is relatively common and does not pose any health risks .
-however , if a person experiences an ectopic heartbeat , that might indicate a more serious heart condition .

392
Q

what happens in atrial fibrillation ?

A

-in atrial fibrillation , irregular waves of electrical excitation pass over the atria .
-this causes the atria to contract randomly and rapidly up to several times per minute .

393
Q

is the electrical excitation transmitted to the ventricles ?

A

no , as you can see , the ventricles contract less frequently m than the atria .
-as the normal rhythm of he heart is disrupted ,atrial fibrillation is a type of arrhythmia .

394
Q

how is atrial fibrillation treated ?

A

atrial fibrillation is treated with medication or surgery .

395
Q

GILLS CONTINUED

A

Many pairs of gill filaments extend from each gill arch .
- gill filaments are covered with numerous gill lamellae which are also called gill plates .
Hill lamellae are where gas exchange takes place .

396
Q

GILLS CONTINUED

A

Many pairs of gill filaments extend from each gill arch .
- gill filaments are covered with numerous gill lamellae which are also called gill plates .
Hill lamellae are where gas exchange takes place .

397
Q

Gas exchange lart four fish

A

Water flows between the fill lamellae , oxygen diffuses from the water , into the bloodstream . And carbodnxifoide diffuses from blood stream to waye d

398
Q

Gas exchange lart four fish

A

Water flows between the fill lamellae , oxygen diffuses from the water , into the bloodstream . And carbodnxifoide diffuses from blood stream to waye r

399
Q

Gill lamellae are adapted for efficient diffusion of gases - adaption 1

A

Firstly girll lamellae have a MASSIVE surface area for gases to diffuse over time.

400
Q

Gill lamellae are adapted for efficient diffusion of gases - adaption 1

A

Firstly girll lamellae have a MASSIVE surface area for gases to diffuse over time.

401
Q

Gill lamellae adaptation 2

A

There is a very short diffusion distance through the walls of the lamellae and blood stream.

402
Q

Gill lamellae adaptation 2

A

There is a very short diffusion distance through the walls of the lamellae and blood stream.

403
Q

Gill lamalelae adaption 3

A

They have an extensive network of blood capillaries .

404
Q

Gas exchange in fish part 5

A

Once oxygen diffuses into the blood it is carried away , and this maintains a steep conecnrtrarion gradient for oxygen

405
Q

Gas exchange in fish part 5

A

Once oxygen diffuses into the blood it is carried away , and this maintains a steep conecnrtrarion gradient for oxygen

406
Q

Another way thag bony fish are adapted for efficient diffusion of gas .

A

Counter current exchange system

407
Q

Another way thag bony fish are adapted for efficient diffusion of gas .

A

Counter current exchange system

408
Q

In order to understand counter current exchange system need to take a closer look at the full lamellae .

A

Blood with a LOW CONC of oxygen passes into the capillaries of the hill lamellae .

  • as blood passes through the full lamellae oxygen diffuses from the water into the blood .
409
Q

In order to understand counter current exchange system need to take a closer look at the full lamellae .

A

Blood with a LOW CONC of oxygen passes into the capillaries of the hill lamellae .

  • as blood passes through the full lamellae oxygen diffuses from the water into the blood .
410
Q

In order to understand counter current exchange system need to take a closer look at the full lamellae . Part two

A

Oxygen rich blood now passes out of the hill lamellae and leaves the gills .
Key : the FLOW OF BLOOD is opposite direction to flow of water .

/ as the blood and water move in opposite directions this is called a counter current system .

() blood uo n down and —-> water

411
Q

In order to understand counter current exchange system need to take a closer look at the full lamellae . Part two

A

Oxygen rich blood now passes out of the hill lamellae and leaves the gills .
Key : the FLOW OF BLOOD is opposite direction to flow of water .

/ as the blood and water move in opposite directions this is called a counter current system .

() blood uo n down and —-> water

412
Q

One major advantage of a counter current system

A

It always a maintains a steep conc gradient for oxygen .

413
Q

One major advantage of a counter current system

A

It always a maintains a steep conc gradient for oxygen .

414
Q

In fish , what would happen if blood and water flow in same direction !

A

Parallel flow

Initially water has a much greater concentration than blood so high diffusion from water to blood teen .

However , after a short distance the concentration of oxygen is the same on both blood and water , acid digs call fhis equilibrium at this point diffusion stops

SO NO MORE THAN 50% of the available oxygen in the water can diffuse into the blood. .

415
Q

At HWOEBER if the blood flows in the opposite direction to water in case hony fish

A

There is ALWAYS A CONCNETRATION HRSIDEKT FOR OFYGEN SO EWUOLIBORUM IS NEVER EACHES AND

DIFDUSION FAKES PLACE RIGHT ACROSS THE LENGTH OF LAMELLAE WITH a countercurrent flow up to around 80% of ofygen in water diffused into the blood stream .

416
Q

How bony fish maintain constant water flow through the gas exchange system ?

A

In non bony fish like shark the flow of water theu the moth and over the gills is caused by fish swimming forward but bony fish evolved a different mechanical which allows water flow to occur even when fish is not swimming

417
Q

How bony fish maintain constant water flow through the gas exchange system ?
(2)

A

Wheh a bony fish opens its mouth wayer flows into the mouth space , which is also called BUCCAL CAVITY

  • the floor of the bucks csviity drops down increasing the volume for available water
418
Q

How bony fish maintain constant water flow through the gas exchange system ?
(2)

A

Wheh a bony fish opens its mouth wayer flows into the mouth space , which is also called BUCCAL CAVITY

  • the floor of the bucks csviity drops down increasing the volume for available water
419
Q

(3) How bony fish maintain constant water flow through the gas exchange system ?

A

The fish then shuts the operculum . And increase the volume of the operculuf cavity which contains the gills .

  • due to the increased volume the pressure in the opercular cavity falls , at the same time the floor of the buccal cavity lifts upwards .

-

420
Q

(3) How bony fish maintain constant water flow through the gas exchange system ?

A

The fish then shuts the operculum . And increase the volume of the operculuf cavity which contains the gills .

  • due to the increased volume the pressure in the opercular cavity falls , at the same time the floor of the buccal cavity lifts upwards .

-

421
Q

Part four, how old does bony fish take hold of water flow through the gas exchange system? ?

A

this increases the pressure of the water causing the water to flow over the gills ingot the opercular cavity , now the fish closes its mouth and opens its operculum .

At the same time the sides of the opercular cavity squeeze inwards on the water , incresss the pressure of water , forcing it out of the operculum.

422
Q

Part four, how old does bony fish take hold of water flow through the gas exchange system? ?

A

this increases the pressure of the water causing the water to flow over the gills ingot the opercular cavity , now the fish closes its mouth and opens its operculum .

At the same time the sides of the opercular cavity squeeze inwards on the water , incresss the pressure of water , forcing it out of the operculum.

423
Q

Now return back to insects !!!

A

Hehehe

424
Q

What is a spirometer

A

Lung volumes can be measured using a sprig meter , this is a device that measures the movmemenf of air in and out of the longs as a Perok breathes .

During inspiration aid ks drawn from the chamber’s so lid moved down air returns to chambers raiding the lid during expiration .

Co2 exhaled passing into soda like which absorbs co2 allowing the masient ox ox hehe consumption .

425
Q

What is a spirometer

A

Lung volumes can be measured using a sprig meter , this is a device that measures the movmemenf of air in and out of the longs as a Perok breathes .

During inspiration aid ks drawn from the chamber’s so lid moved down air returns to chambers raiding the lid during expiration .

Co2 exhaled passing into soda like which absorbs co2 allowing the masient ox ox hehe consumption .

426
Q

Precautions that must be taken when you get spirometer

A

The tablet should be healthy and in particular free from last month.

The soda lime should be fresh and functioning.

There should be no leaks in operator as invalid results.

Should be sterilised.
The water chamber must not be overfilled.

427
Q

Precautions that must be taken when you get spirometer

A

The tablet should be healthy and in particular free from last month.

The soda lime should be fresh and functioning.

There should be no leaks in operator as invalid results.

Should be sterilised.
The water chamber must not be overfilled.

428
Q

What does the total lung volume consist of?

A

The total log consist of the vert capacity, which can be measured at the residual volume, which cannot be measure uring the spirometer

429
Q

What is the vital capacity? Also check the graph.

A

What capacity is the maximum volume of air that could be moved by the long breath. This is taking deep breath and exploring all the possible belts. Capacity depends upon a number of factors such as
The size of
Bullet point agent gender.
The level exercise capacity may rise and athletes usually for everyone it’s usually 2.5 to 5.0 decimetres cubed

430
Q

What is the vital capacity? Also check the graph.

A

What capacity is the maximum volume of air that could be moved by the long breath. This is taking deep breath and exploring all the possible belts. Capacity depends upon a number of factors such as
The size of
Bullet point agent gender.
The level exercise capacity may rise and athletes usually for everyone it’s usually 2.5 to 5.0 decimetres cubed

431
Q

What is the residual volume?

A

The residual volume is the volume of air that remains in the lungs, even after forced expiration, the air remains in the airways of this approximately 1.5 dm cubed

432
Q

What is the residual volume?

A

The residual volume is the volume of air that remains in the lungs, even after forced expiration, the air remains in the airways of this approximately 1.5 dm cubed

433
Q

What is the tidal volume

A

The title volume is the volume of moved in and out with each breath. It is normally the rest. A typical heart of water is 0.5 decimated cubed. This is usually sufficient display all the required body arrest. Check the graph.

434
Q

Oxygen uptake

A

Breathing supplies alternative for respiration remove carbon oxide respiration.

– as a person bruised from the spiral of oxygen is absorbed by the blood replaced by the crocodile.

– This spiral so the volume of the decreases.

Decrease can be observed and measured to trace. We can assume that the volume of carbon dioxide at least and absorbed by the total line equals the volume of ocean absorbed by the blood. Therefore, the grade of the decrease of volume enables us to calculate the road ox optic. Road Oxy optic..

435
Q

Oxygen uptake

A

Breathing supplies alternative for respiration remove carbon oxide respiration.

– as a person bruised from the spiral of oxygen is absorbed by the blood replaced by the crocodile.

– This spiral so the volume of the decreases.

Decrease can be observed and measured to trace. We can assume that the volume of carbon dioxide at least and absorbed by the total line equals the volume of ocean absorbed by the blood. Therefore, the grade of the decrease of volume enables us to calculate the road ox optic. Road Oxy optic..

436
Q

Calculating oxygen uptake from a spirometer trace chrck sheet

A

437
Q

Calculating oxygen uptake from a spirometer trace chrck sheet

A

438
Q

Breathing rate

A

The breathing rate can also be measured by a spirometer trace, possibly cure a number of peaks in each minute, so it’s usually 12 to 14 breaths per minute at rest

439
Q

Breathing rate

A

The breathing rate can also be measured by a spirometer trace, possibly cure a number of peaks in each minute, so it’s usually 12 to 14 breaths per minute at rest

440
Q

Oxygen uptake

A

So Oxid table depend on the number of factors are higher oxide. Obtainable result from increase, such as during exercise when the muscles are spiral.
Increase result from increased breathing rate and deeper breaths.

441
Q

Oxygen uptake

A

So Oxid table depend on the number of factors are higher oxide. Obtainable result from increase, such as during exercise when the muscles are spiral.
Increase result from increased breathing rate and deeper breaths.