Module 3 (Biological Membrane Functions) Flashcards
There are two major types of membrane proteins: i_____ proteins and p______ proteins
Integral proteins and peripheral proteins
P______ proteins are attached to the s______ of the membrane
Peripheral, surface
I_____ proteins are e_____ in the cell membrane
Integral, embedded
All bio membranes are a_______; this is evident in the p_____ composition of the two leaflets of the phospholipid bilayer, as well as the integral p_____ orientation
Asymmetrical, phospholipid, protein
Full c_____ (positive or negative) creates a sphere of h______ around the charged particle, which causes the ions to be unable to diffuse through the barrier on their own
Charge, hydration
Integral proteins have a h______ a_____ h____ structure; the hydrophilic backbone of the protein
Hydrophobic alpha helic
P_______ t_______: molecules move with their concentration gradient (from a high area of concentration to an area of low concentration) through d_________
Passive transport, diffusion
A_______ t_______: molecules moved against their concentration gradient, energy (____) is used
Active transport, ATP
The c________ g______ is the driving force behind almost all membrane transport. It’s the difference in the concentration of molecules between the two sides of the m_______
Concentration gradient, membrane
S_______ d______ doesn’t require proteins, occurs in small uncharged particles
Simple diffusion
F_______ d_____ is a form of passive transport where molecules are moved across a membrane through the use of i_____ p____. The driving force of the transport is simply the c______ g_____ of the molecule
Facilitated diffusion, integral proteins, concentration gradient
M______ p______ make it possible to transport ions and large polar molecules across biological membranes
Membrane proteins
C_______ p______ have a central pore lined with p_____ amino acids on the inside of the channel and n______ amino acids on the exterior of the channel
Channel proteins, polar, nonpolar
Facilitated diffusion is often r_______. Ion channels are highly specific for an ion. Most are gated, can closed or open; channel opens when stimulated to change s____
Regulated, shape
Facilitated diffusion gets help from c_____ p______. They transport p______ molecules such as glucose across membranes in both directions. Glucose b____ to the proteins, which causes it to change shape and release glucose on the other side
Carrier proteins, polar, binds
In active transport, there are two types: p_____ and s_____
Primary and secondary
P______ active transport requires direct e_____ investment, so that ____ can be used to move molecules against their concentration gradient
Primary, energy, ATP
S_______ active transport: energy comes from an ion c______ g______ established by primary active transport. This moves molecules a_____ their concentration gradient. Does not need ATP
Secondary, concentration gradient, against
An example of active transport is the Na+ - K+ p____
Pump
An example of secondary active transport is the transfer of g_____ and sodium
Glucose
There are t____ kinds of transporter proteins
Three
Carries one specific ion or molecule (transporter protein)
Uniporter
Carries two different ions or molecules, both in the same direction (transporter protein)
Symporter
Carries two molecules in opposite directions (transporter proteins
Antiporter
The diffusion of water through a semipermeable membrane
Osmosis
If two solutions are separated by a membrane that allows water but not solutes to pass through, the water will try to create an e_____ concentration (isotonic solution) by d____ to the area that has less water concentration
Equilibrium, diffusing
A solution that has an equivalent solution concentration
Isotonic solution
Dilute solutes outside of cell. Animal cells may burst when placed in a solution of this kind
Hypotonic solution
In facilitated diffusion of water, water moves through water channels called a______
Aquaporins
Large molecules enter and leave a cell through e_____
Endocytosis
M________ are transported through endocytosis, where the plasma membrane f______ around the material, forming a vesicle.
Macromolecules, folds
There are t____ types of endocytosis:
Three
P______: molecules or entire cells are engulfed. Resulting phagosome f___ with a lysosome (Type of endocytosis)
Phagocytosis, fuses
P______: a vesicle forms to bring s______ dissolved substances or fluids into a cell. Vesicles don’t necessarily fuse with a lysosome. (Type of endocytosis)
Pinocytosis, small
R_______ m_______ e_______: highly s_____ in bringing in foreign substances. Depends on receptor p_____ to bind specific ligands. Sites are called coated pits
Receptor mediated endocytosis, specific, proteins
E_______: material in vesicles are e______ from a cell
Exocytosis
Osmosis doesn’t depend on the type of molecule; it depends on the n_____
Number