module 2 Flashcards

1
Q

substance use disorder criteria

A

social impairments
risky use
impaired control
withdrawal
tolerance

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2
Q

individual may use the substance in physically hazardous situations or use substance despite physiological or psychological problems caused by the use

A

risky use

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3
Q

impaired control

A

individual may have persistent craving for the substance

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4
Q

the state in which stopping abruptly or reducing the dose of a given drug produces non physical symptoms

A

addiction

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5
Q

reward system of the brain

A

limbic system

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6
Q

characteristics of addictive drugs

A

increase dopamine
produce novelty
reduce anxiety

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7
Q

drugs that increase dopamine

A

cocaine
amphetamines
nicotine
caffeine
morphine
heroine
oxycodone
alcohol
cannabis

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8
Q

drugs that increase novelty

A

lysergic acid diethylamide lsd
ecstasy or mdma

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9
Q

drugs that reduce anxiety

A

benzodiazepine
barbiturates

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10
Q

stimulant withdrawal symptoms

A

sleepiness
muscle pain
anxiety
tremors
low mood
suicidal ideation
cardiovascular problems

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11
Q

opioid withdrawal symptoms

A

sweating
muscle aches
agitation
diarrhea
abdominal cramping
vomiting

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12
Q

drug tolerance

A

the state in which repeated administration of a given dose of a drug has progressively less pharmacological effect. or a state. in which the dose of a drug must be increases to obtain the same magnitude of pharmacological effect as that was produced by the original drug dose

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13
Q

factors influencing substance use disorder

A

genetic
pre existing disorders
environmental
developmental

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14
Q

what drug does not have withdrawal symptoms

A

hallucinogens

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15
Q

substance misuse

A

using the drug in ways or amounts other than what was prescribed or against social norms

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16
Q

mdma effects

A

a derivative of methamphetamine that is often misused. it fosters the feeling of intimacy and empathy while improving intellectual capacities. a neurotoxin causing neuronal damage, long lasting

17
Q

effects of amphetamines on CNS

A
  • decreased threshold for transmitting sensory input to the cerebral cortex, leading to cns excitation
  • feeling of euphoria or reward
  • temperature regulation and feeding centre modifications leading to appetite suppression
  • increase in aggressive behaviour and mood swings
18
Q

mechanism of action of nicotine

A

nicotine stimulates nicotinic receptors at the synapse similar to acetylcholine.
activation of nicotinic receptors increases psychomotor activity, cognitive function, attention, and memory. mediates release of dopamine and serotonin

19
Q

long term effects of smoking

A

cardiovascular diseases
lung disease
cancer

20
Q

what types of cancer does smoking increase

A

lung, oral cavity, throat,. bladder and uterus

21
Q

caffeine competes with ______

A

adenosine

22
Q

amphetamines mechanism of action

A

blocks vesicular monoamine transporters VMAT, increases dopamine/norepinephrine at synapse

23
Q

cocaine mechanism of action

A

blocks reuptake of dopamine, increases dopamine at synapse

24
Q

nicotine mechanism of action

A

stimulates nicotinic receptors

25
Q

nicotine mechanism of action

A

stimulates nicotinic receptors

26
Q

caffeine mechanism of action

A

competitive inhibitor at adenosine receptors, prevents inhibition

27
Q

performance enhancing drugs

A

amphetamines, anabolic steroids, benzodiazepines, blood doping, erythryopoietin and diuretic

28
Q

anabolic steroids

A

used by athletes to increase muscle mass and strength. testosterone is an anabolic steroid. synthetic anabolic steroids have reduces androgen effected but maintain anabolic effects while testosterone has both

29
Q

anabolic steroids produce an_____response. to help athletes maintain muscle mass by preventing muscle tissue from breaking down

A

anti catabolic response

30
Q

What system in the brain in the reward system associated with dopamine

A

Limbic system

31
Q

3 Characteristics of addictive drugs

A

Increases dopamine
Produces novelty
Reduces anxiety

32
Q

effects of anabolic steroids (synthetic)

A

increase muscle mass and strength, reduces androgenic effects, increase anabolic effects.

33
Q

when would anabolic steroids be used in sports

A

they are used in sports such as football, weight lifting, running and gymnastics

34
Q

mechanism of action of anabolic steroids

A

anticatabolic - produce an anticatabolic response. prevents muscle protein degradation, allowing athletes to maintain muscle mass

anabolic - anabolic effects of drug result in protein production

motivation - produce aggressive behaviour, roid rage. beneficial for sports like football

35
Q

effects of anabolic steroids low to moderate dose and large dose

A

effects on inexperienced weightlifter would be less than exercise program
in athletes peak of training, large doses combined with diet in protein significantly increases lean body mass, body weight and strength. aggressive behaviour induced by steroids contributes to their performance enhancement effects

36
Q

toxicities of anabolic steroids

A

moodswings
severe acne
cardiovascular disease - increase cholesterol
altered liver function - hepatitis, liver failure, liver cancer
reduced testosterone levels - blocks release of gonadotropin releasing hormone, reducing testosterone and sperm production.