Module 10 Nervous System and Control of Ventilation Flashcards

1
Q

Both the somatic nervous system (SNS) and autonomic nervous system (ANS) include components in the CNS and PNS.

what are two ways the somatic nervous system conduct information?

A

Somatic sensory pathways conduct toward integrators in the CNS (Information)

Somatic motor pathways conduct information towards somatic effectors. (response)

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2
Q

Both the somatic nervous system (SNS) and autonomic nervous system (ANS) include components in the CNS and PNS.

what are pathways for the ANS?

A

Visceral sensory pathways conduct information toward CNS integrators

Sympathetic AND parasympathetic pathways conduct information toward autonomic effectors.

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3
Q

Efferent vs Afferent?

A

Efferent = away

Afferent = towards

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4
Q
A
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5
Q

Central nervous system (CNS)

A

Brain + Spinal Cord

integrates sensory information, evaluates it, and initiates an outgoing response.

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6
Q

Peripheral nervous system (PNS)

A

Cranial nerves originate from the brain (12)
Spinal nerves originate from the spinal cord (31)

Basically the relay point for the CNS

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7
Q

Somatic Nervous System

A

Consists of somatic motor (efferent) and somatic sensory (afferent) divisions.

Motor: towards effectors (skeletal muscles)

Sensory: feedback to CNS

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8
Q

What nerves innervate the respiratory system?

A

Phrenic nerves

Intercostal nerves

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9
Q

Phrenic nerves

A

C3-C4-C5

Injuries in this region can paralyze the diaphragm

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10
Q

What does innervate mean?

A

To supply with nerves, or to stimulate nerves/organs

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11
Q

ANS major function

A

To regulate heartbeat, smooth muscle contraction, and glandular secretions to maintain homeostasis

ANS = Involuntary

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12
Q

2 divisions of the ANS

A

Sympathetic nervous system

Parasympathetic nervous system

Both are efferent.

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13
Q

Sympathetic nervous system

A

Prepares the body to deal with immediate threats to the interval environment;

Produces the flight or flight response

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14
Q

parasympathetic nervous system

A

coordinates the body’s normal resting activity’s;

Rest and repair

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15
Q

West zones of the lung: zone 1

A

Where alveolar pressure is higher than arterial or venous pressure

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16
Q

West zones of the lung: zone 2

A

Where arterial pressure higher than alveolar and venous, a relationship that changes during the respiratory cycle

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17
Q

West zones of the lung: zone 3

A

where both arterial and venous pressure is higher than alveolar

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18
Q

Excitable cells do what?

A

Initiate and conduct impulses that make nervous system function

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19
Q

Cell body: what are 2 main functions?

A

1.provide proteins for maintaining and regenerating
nerve fibers

  1. Provide protein muscles (neurotransmitters) needed for transmission of nerve signals from one neuron to another.
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20
Q

Neurotransmitters are packed into?

A

Vesicles.

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21
Q

Structure of a typical neuron (an image)

A
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22
Q

Two types of signals transmitted at the Synapse from one to another

A

Electrical and Chemical

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23
Q

Which synaptic transmission uses action potentials to directly between cells?

A

Electrical

24
Q

How do Chemical synapses work?

A

Neurotransmitters (chem signals) are sent across a tiny gap to postsynaptic cells which induces action potentials

25
3 types of Neurotransmitters
Acetylcholine Amines Amino acids
26
4 types of Amines and function
In brain; affect learning, emotions, motor control. Dopamine, Norepinephrine, serotonin, histamine.
27
Acetylcholine function
In Brain + body; sends signals to neurons, muscle cells, glands
28
2 types of Amino acids (most common)
glutamate and Gaba most common neurotransmitter in CNS In PNS, amino acids are stored in synaptic vesicles.
29
Autonomic nervous system: what is sympathetic/parasympathetic referred to as?
Sympathetic = Adrenergic Parasympathetic Cholinergic
30
All preganglionic fibers are cholinergic, secreting acetylcholine (ACH), which binds with nicotinic receptors on postganglionic fibers. what does the sympathetic postganglionic do differently?
Sympathetic postganglionic fibers are adrenergic, secreting norepinephrine (NE), which binds with adrenergic alpha and beta receptors.
31
Sympathetic postganglionic fibers are adrenergic, secreting norepinephrine (NE), which binds with adrenergic alpha and beta receptors. what does the preganglionic do differently?
cholinergic secrete acetylcholine (ACH), which binds with nicotinic receptors on postganglionic fibers.
32
Cholinergic (para) innervate what and release which neurotranmistter?
Innervate: smooth airway muscles, mucous glands, pulmonary vasculature Neurotransmitter = Acetylcholine
33
Cholinergic overstimulation?
Bronchospasm + Increased mucous production and thickness
34
Adrenergic (symp) innervate what and release which neurotransmitter?
innervate adrenal medulla (secrete hormones like dopamine) Neurotransmitter = norepinephrine Cause bronchodilation
35
Regulation of ventilation is automatic, what controls it?
Primarily the Medulla The pons + spinal chord are also involved.
36
4 components of ventilation from the medulla
(Top down) Pneumotaxic center Apneustic center Dorsal resp. group. [DRG] ventral resp. group. [VRG]
37
Dorsal Resp. Group [DRG] is the main inspiratory stimuli, where are nerve impulses sent?
Diaphragm and external intercostal muscles.
38
What sends sensory impulses to Dorsal Resp. Group [DRG]?
vagus and glosspharyngeal nerves peripheral chemoreceptors = changes in pH + gases proprioceptors = changes in muscles + joints.
39
Ventral Resp. Group [VRG] contains both inspiratory ad expiratory neurons, where/which are impulses are sent?
Motor--->laryngeal and pharyngeal muscles = diaphragm + external intercostal TLDR; I'm assuming it means inspiratory muscles.
40
Ventral Resp. Group [VRG] what is stimulated during expiration?
internal and abdominal muscles
41
What does the Inspiration ramp signal mean?
DRG and VRG (dorsal and ventral resp. group) are fired gradually by a ramp signal from neurons.
42
Pons resp. centers interactions with the medulla?
Pons modifies output of medullary centers but can't make rhythmic breathing on its own.
43
pontine resp. centers: apneustic center function
allows gradual prolonged inspiration + Prevents inspiratory neurons from switching off
44
pontine resp. centers: pneumotaxic center function
off switch for normal inspiration it switches off the apneustic center
45
What two centers from the pons control depth of inspiration
apneustic center and pneumotaxic center
46
Reflex control breathing: Hering-Breuer inflation reflex is generated in smooth muscles of large/small airways. what happens?
When stretch occurs receptors send inhibitory impulses to DRG to stop further inspiration active with exercise. Vagus nerve pathway
47
Deflation Reflex
Collapse of lungs stimulates strong inspiratory effort. vagus nerve pathway
48
Head paradoxical reflex
helps maintain large Vt during exercise, sighs, or first breaths in newborns.
49
Add cards on receptors
50
When hypoxia increases sensitivity of peripheral chemoreceptors to blood h+ what events subsequently follow?
Increases the fire rate-->increase in minute ventilation (MV)
51
CO2 and Cerebral blood flow: why is hyperventilation dangerous for head injuries?
patients with head trauma have low cerebral perfusion
52
CO2 and Cerebral blood flow: mech. ventilation use controls what?
intracranial pressure for patients with head injuries and high intracranial pressure [ICP].
53
CO2 and Cerebral blood flow: increase PaCO2 does what?
dilates cerebral vessels = increasing blood flow
54
CO2 and Cerebral blood flow: decreased PaCO2 does what?
constricts cerebral vessels reducing blood flow
55
What neurons in the medulla generate basic cyclic breathing?
DRG and VRG (Dorsal/ventral resp. group)
56
Which impulses inhibit apneustic center and intern inspiration neurons of the DRG What happens as a result?
pneumotasic center. shortened inspiration time + increase RR
57
What prevents medullary inspiration neurons from switching off, creating prolonged, gasping inspiration?
Apneustic center