Intro to Pharmacology 14 Flashcards
Drug Administration phase
Delivery
Pharmacokinetic phase
Drug action
Pharmacodynamic phase
mechanism of action which causes the effects
What are 5 receptor sites
Adrenergic (andromimetic)
Antiadrenergic
Cholinergic
Anticholinergic
Muscarinic
Adrenergic vs Antiadrenergic drug sites
Adrenergic:
Drug that stimulates a receptor responding to
norepinephrine or epinephrine
Antiadrenergic blocks receptors for norepinephrine/epinephrine
Cholinergic vs Anticholinergic drug sites
Cholinergic: drug that stimulates a receptor for acetylcholine
Anticholinergic blocks receptors for acetylcholine.
Muscarinic drug sites
drug that stimulates acetylcholine receptors, specifically at parasympathetic nerve ending sites
-because cholinergic receptors exist at autonomic ganglia
Sympathetic vs parasympathetic system
Sympathetic nervous system = fight or flight
Parasympathetic nervous system inhibits the body from overworking and restores the body to a calm and composed state.
Difference between sympathetic vs parasympathetic nervous system
Sympathetic nervous system: what does fight or flight actually entail?
When stimulated, the nerves prepare the body for stress by increasing heart rate, blood flow (to muscles), and decreasing blood flow to the skin.
parasympathetic nervous system is often connected to a state of relaxation, what does this entail?
When the PNS is activated, it slows our heart, breathing rate, lowers blood pressure, and promote digestion.
It breeds recovery via relaxation.
When would you use a Bronchodilator?
To relieve acute reversible airflow.
-asthma
-obstructive airway diseases
Delivery methods for Relievers
Small volume nebulizers (SVN)
meter dose inhalers (MDI)
Turbohaler
Diskus
4 common relievers
Salbutamol (Ventolin or Airomir)
Terbutaline (Bricanyl)
Salbutamol diskus (ventolin)
What are relievers classified as?
short acting muscarinic antagonist (SAMA)
They’re anticholinergic