Intro to Pharmacology 14 Flashcards

1
Q

Drug Administration phase

A

Delivery

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2
Q

Pharmacokinetic phase

A

Drug action

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3
Q

Pharmacodynamic phase

A

mechanism of action which causes the effects

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4
Q

What are 5 receptor sites

A

Adrenergic (andromimetic)

Antiadrenergic

Cholinergic

Anticholinergic

Muscarinic

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5
Q

Adrenergic vs Antiadrenergic drug sites

A

Adrenergic:
Drug that stimulates a receptor responding to
norepinephrine or epinephrine

Antiadrenergic blocks receptors for norepinephrine/epinephrine

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6
Q

Cholinergic vs Anticholinergic drug sites

A

Cholinergic: drug that stimulates a receptor for acetylcholine

Anticholinergic blocks receptors for acetylcholine.

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7
Q

Muscarinic drug sites

A

drug that stimulates acetylcholine receptors, specifically at parasympathetic nerve ending sites

-because cholinergic receptors exist at autonomic ganglia

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8
Q

Sympathetic vs parasympathetic system

A

Sympathetic nervous system = fight or flight

Parasympathetic nervous system inhibits the body from overworking and restores the body to a calm and composed state.

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9
Q

Difference between sympathetic vs parasympathetic nervous system

A
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10
Q

Sympathetic nervous system: what does fight or flight actually entail?

A

When stimulated, the nerves prepare the body for stress by increasing heart rate, blood flow (to muscles), and decreasing blood flow to the skin.

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11
Q

parasympathetic nervous system is often connected to a state of relaxation, what does this entail?

A

When the PNS is activated, it slows our heart, breathing rate, lowers blood pressure, and promote digestion.

It breeds recovery via relaxation.

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12
Q

When would you use a Bronchodilator?

A

To relieve acute reversible airflow.
-asthma
-obstructive airway diseases

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13
Q

Delivery methods for Relievers

A

Small volume nebulizers (SVN)
meter dose inhalers (MDI)
Turbohaler
Diskus

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14
Q

4 common relievers

A

Salbutamol (Ventolin or Airomir)

Terbutaline (Bricanyl)

Salbutamol diskus (ventolin)

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15
Q

What are relievers classified as?

A

short acting muscarinic antagonist (SAMA)

They’re anticholinergic

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16
Q

MDI vs DPI

A

MDI’s deliver faster but cause more irritants

DPI’s are easy to use, but aren’t as fast.

17
Q

Factors that effect delivery of inhaled meds

A

Particle size from delivery device (1-5 microns)

Inspiratory flow rate

Depth of inhalation

Inspiration pause

18
Q

Inotrope

A

drugs that tell your heart muscles to beat or contract with more power or less power, depending on whether it’s a positive or negative inotrope.

Positive inotropes can help when your heart can’t get enough blood to your body because it is too weak to pump the amount of blood your body needs