Module 10 HCV Flashcards
When was the first identified HCV ?
1988
HCV is…?
Containing single strand of RNA virus, transmitted by percutaneous contact through injection drug use or exposure to infected blood or blood products. ( commonly spread through blood transfusions, organ transplants )
In 2013 …. ?
29,718 new hepatitis C virus infections in United States.
CDC estimates that ….?
2,7-3,9 million people in the U.S have chronic HCV infection.
The risk of seroconversion after percutaneous occupational exposure is ….?
Approximately 1,8%, if the source blood is seropositive for HCV.
This is the considerably HIGHER than the risk of percutaneous occupational exposure due to HIV seropositive blood, LOWER than the risk of seroconversion after percutaneous occupational exposure to HBV seropositive fluids.
HCV acute symptoms ?
Flu-like symptoms, joint aches, mild skin rash, grey colored stool, darker than normal urine color. Practitioners should be aware that less than 30% of those infected with HCV manifest acute disease symptoms.
What is the 60% about HCV ?
Individuals with a history of injection drug use represent 60% of those infected. As many as 80% of injections drug users are found to be infected HCV and are often co-infected with HIV 30-50%.
Transmitted by sexual contact 15%…?
HCV
HCV is spread from…?
Mother to baby. About 10% of those infected have no recognizable source of infection.
HCV is most efficiently transmitted by…?
Exposures that involve direct passage of blood through the skin, particularly with hollow-bore needles.
HCV can remain viable outside the body for….?
4 - 5 days
How many percent for HCV infection without further problems?
15-25% of those infected clear their HCV infection without further problems.
HCV chronic infection and chronic hepatitis?
75-85% will develop chronic infection
60-70% will go on to develop chronic hepatitis
Cirrhosis of the liver occurs in….?
At least 5-20% of patients over 20-30 year period
Hepatocellular carcinoma ( liver cancer ) occurs in ….?
1-5% of cases