Module 1: Basic tissue types: Connective tissue Flashcards
connective tissue
basic tissues that provides structural and metabolic support for tissues and organs throughout the body
carries blood vessels and mediates exchange of materials between tissues and circulatory system
what is connective tissue composed of
extracellular matrix (fibers produced by specialized support cells and ground substance [glycoproteins, fibronectin, glycosaminoglycans])
what is the primary glycosaminoglycans
hyaluronic acid
able to hold large volume of tissue fluids within its meshwork
forms medium for transport of materials between tissues and circulatory system
stains clear
specialized support cells
fibroblasts - secrete extracellular matrix
chondrocytes - secrete extracellular matrix of cartilage
osteocytes - secrete extracellular matrix of bone
myofibroblasts - contractile and secretory function
adipocytes - fat storage and cushioning
mast cells/ macrophages - convey immunity
Classification is based on
the fibre types that predominates
collagenous
elastic
collagenous
type I: makes up 90% of collagen in tissue; found in dermis of skin, tendons, ligaments, bone; described as dense or loose based on density
type III: formerly reticulin fibers; collagen fibrils aggregate to form collagen fibers. Results in very fine branching fibrils that provide support for highly cellular tissue (ex. liver)
Elastic
fibers composed of amorphous protein, elastin, a glycoprotein and microfibrils
found in walls of arteries
may also form sheets of elastic laminae
Also found in skin and urinary bladder
Adipose tissue
Fat cells; adipocytes
found in most connective tissue
function as energy reserve and cushioning, insulation
White: main type in adults
brown: main types in newborns and small amount in adults