Module 1 Flashcards
Anatomy
The study of the structure of the body
Physiology
The study of how the body parts function together
Function of the Nervous System
The nervous system receives and processes information and sends out signals to muscles and glands to elicit an appropriate response. In this way, the nervous system integrates and controls the other systems of the body.
2 Parts of the Nervous System
Central Nervous System (CNS) & Peripheral Nervous System (PNS)
How are the parts of the CNS protected?
The skull protects the brain and the vertebrae protects the spinal cord
Collections of cell bodies in the CNS are called _____, and the collection of nerve axons in the CNS are called _____.
Nuclei & Tracts
What is included in the PNS?
Cranial nerves and the spinal nerves
Collections of cell bodies inside the PNS are called ____, and the collection of nerve axons in the PNS are called ___.
Ganglia & Nerves
2 Divisions of the PNS
Sensory (afferent) & Motor (efferent)
Describe the movement of nerve impulses in the PNS
The PNS receives impulses from the sensory organs via the afferent division and the relays signals/impulses from the CNS to muscles and glands via the motor division
2 Divisions of the Motor (efferent)
Somatic & Autonomic
What is Controlled by the Somatic Nervous System?
Skeletal muscles, skin, and joints
What is Controlled by the Autonomic Nervous System?
The glands and smooth muscles of the internal organs
2 Divisions of the Autonomic Nervous System
Sympathetic & Parasympathetic
What is the Function of the Sympathetic Nervous System
Activates and prepares the body for vigorous muscular activity, stress, and emergencies
What is the Function of the Parasympathetic Nervous System
Generally operates during normal situations, permits digestion, and conserves energy
Label the components of a Neuron
Dendrite
Soma (cell body)
Nucleus
Myelin Sheath
Axon
Axon Terminals
3 Unusual Characteristics of Neurons
- Neurons do not undergo mitosis
- Can survive a person’s entire lifetime
- Can only survive minutes w/out oxygen
All Neurons Must Contain
Dendrites, cell body, and axon
Structure and Function of Neuron Cell Body
Synthesizes all nerve cell products, consists of a large nucleus w/ surrounding cytoplasm containing the normal organelles
Structure and Function of the Dendrite
Numerous short extensions that spread from the cell body to receive info from other neurons conducting those nerve impulses toward the cell body
Describe the Axon
Conducts nerve impulses away from cell body to its axon terminals where it is emitted across a synapse to the dendrite of another neuron
Composed of cells like the cell body but lack ER
Function and Site of Synthesis & Storage of Neurotransmitters
Chemicals stored in secretory vesicles at the end of axon terminals. When they are released by the axon terminal vesicles, they carry the transmission of the nerve impulse from one neuron to another
What is a Synapse?
A gap btwn 2 neurons
A post-synaptic neuron is a neuron that is found ___ the synapse
After
___ neurons have 3 or more extensions from the cell, 1 axon, and many dendrites
Multipolar
___ neurons have a central cell and 2 extensions
Bipolar
___ neurons have 2 extension off the cell body which branches into 2: one central process running to the CNS and another peripheral process running to the sensory receptor
Unipolar (pseudounipolar)
___ neurons are unipolar and function to carry info from the PNS to the CNS
Sensory
What type of neuron is also called Association Neurons?
Interneurons
___ neurons send messages from the CNS to the PNS
Motor
Function of Neuroglial Cells
They are support cells, helping neurons to enable them to thrive in their environment
PNS Neuroglial Cell Types
Schwann Cells
Satellite Cells
T or F: axons cannot regenerate in the PNS
False. Can regenerate in the PNS
T or F: Myelin sheath is continuous and has no gaps
False
4 Types of Support Neuroglial Cells in CNS
Ependymal Cells
Oligodendrocytes
Astrocytes
Microglial Cells
Function of Ependymal Cells
Circulate cerebrospinal fluid and allow fluid exchange btwn brain, spinal cord, and CSF
Function of Oligodendrocytes
Act as insulation for CNS axons
Function of Astrocytes
Control chemical environment of neurons by wrapping around blood capillaries, forming blood-brain barrier
Function of Microglial Cells
Protect the CNS by scavenging dead cells and infectious microorganisms
Technical term used to describe a nerve impulse and what causes the impulse?
Action potential, and is caused by the movement of unequally distributed ions on either side of an axon’s plasma membrane
What is a resting potential and how is it maintained?
The axon plasma membrane is polarized, one side has a different charge than the other. This difference is called a resting potential, the inside of the axon’s cell membrane is 70 millivolts less than the outside of the membrane. A sodium-potassium pump using active transport carries ions across the plasma membrane and because 3 Na+ ions are pumped out as 2 K+ ions are pumped in, a relative positive charge develops and is maintained on the outside of the membrane.
4 Steps of an Action Potential
- Resting Potential
- Depolarization
- Repolarization
- Afterpolarization (hyperpolarization)
Describe what happens during Depolarization
Sodium gates open and Na+ rushes into the axon and the inside becomes more positive than the outside causing the membrane to become positive
Describe what happens during Repolarization
The sodium gates close and potassium gates open allowing K+ to rush out. Returns a negative charge to the inside of the axon re-establishing the negative potential
Describe what happens during Afterpolarization
The K+ gates are slow to close and there is an afterpolarization undershoot of potential
What causes the difference in intensity of a sensation?
The number of neurons stimulated and the frequency with which they are stimulated
T or F: An impulse from a neuron moves in both directions
False
What is meant by neuron signals being electrochemical in nature?
The signal moves from electrical (through the neuron) to chemical (in the synapse) to electrical again once the signal reaches the next neuron
What is the chemical portion of neuron signal transmission?
Neurotransmitters
How is an impulse passed from one nerve cell to another?
When a nerve impulse reaches the end of an axon, neurotransmitters are released into the synapse. These bind with a receptor on the next neuron, opening Na+ gates in the receiving dendrite which causes depolarization and the impulse is carried
What prevents continuous stimulation of a nerve synapse and how is this accomplished?
The short existence of neurotransmitters in the synapse prevents continuous stimulation. Some synapses contain enzymes that rapidly inactivate neurotransmitters and other synapses rapidly absorb the neurotransmitter
What neurotransmitter helps regulate emotional responses and muscle tone?
Dopamine
What neurotransmitter is found at the neuromuscular junctions?
Acetylcholine
Once ACh is released in the NMJ, what happens to cause muscle contraction to occur?
ACh binds to receptors on the muscle fiber that cause sodium channels to open. Sodium rushes into the muscle cell, triggering an action potential which reaches the sarcoplasmic reticulum. Calcium ions are released from the sarcoplasmic reticulum of the muscle cell causing the muscle to contract
Define the term Reflex
Nearly instantaneous, automatic, involuntary motor responses to stimuli occurring inside or outside of the body
Ex: regulating blood sugar, touching hot object and withdrawing hand immediately
Sensory info travels into the spinal cord via the ___ of a nerve
Dorsal root
Gray Matter
Contains the cell bodies of neurons in the spinal cord
White Matter
Contains the axons of neurons in the spinal cord
What does the Dorsal Root Ganglia (DRG) contain?
The cell bodies of sensory neurons
Sensory neurons synapse on cells in the ___ of the spinal cord
Posterior horn
Motor neuron cell bodies are in the ___ of the spinal cord
Anterior horn
Motor neurons (axons) leave the spinal cord via the ___
Ventral root
When does a ventral root transition to a spinal nerve
The spinal nerve roots are formed by the union of dorsal and ventral roots within the intervertebral foramen
Why is a spinal reflex faster than a conscious decision
Spinal reflexes are faster because they involve fewer neurons and the electrical signals only have to travel to the spinal cord and back, instead of the brain
5 components of a Reflex Arc
Receptor
Afferent neuron
Integration center
Efferent neuron
Effector
The stretch reflex utilizes what type of specialized receptor to detect over-stretch?
Muscle spindles
What is the purpose of the stretch reflex?
Protect the muscle against increases in length which may tear or damage muscle fibers