Moduel 3 Flashcards
Outline the milestones of the three stages (trimesters) of prenatal development. (Table 3.1 offers a summary)
First Trimester wk 0-12
- period stops
- breast enlargement, peeing more often
- abnormal (cervix) thickening
Second Trimester wk 12-24
- weight gain, uterus expands
- showing
- fetal movement felt
- sex of baby determined at 13th week
- increased appetite
Third Trimester 24wk to birth
- weight gain
- breast discharge
Understand how dominant, recessive, and sex-linked disorders occur
Dominant disorders are usually manifested in adulthood. Ex: Huntington’s disease a fatal affliction of the nervous system
Recessive disorders affect individuals earlier in life often leading to intellectual disabilities and/or early death.
Ex: phenylketonuria, Tay-Sachs disease, cystic fibrosis, sickle cell disease, red-green colourblindness (7-8% of men but only 0.5% women)
Hemophilia (blood can’t clot) and fragile-x-syndrome (can cause progressive intellectual disability) are serious sex-linked disorders that affect males far more often than females.
Identify common trisomy errors and sex-chromosome anomalies that can affect development.
Trisomy:
- three copies of a specific autosome
- Abnormal numbers of chromosomes and damage to chromosome cause serious disorders such as Down syndrome (21 copy) intellectually delayed
Sex-chromosome anomalies
- may affect sexual development and certain aspects of intelligent functioning
- XXY pattern in Klinefelter’s syndrome (underdeveloped testes and low sperm count
- XO Turners syndrome (female but show stunted growth
Identify the risks associated with teratogenic maternal diseases.
- Teratogens are agents that cause damage to the embryo
- organs most at risk when developing rapidly
- Some diseases contracted by the mother may cause abnormalities or diseases in the child. These include CMV (10% of babies show serious symptoms like deafness, CNS damage), HIV (can be contracted via bloodstream, in birth canal or breastmilk. Infants with this become ill in first 2 years of life), syphilis, genital herpes and gonorrhoea (these three cause genital anomalies. Herpes/Gon can cause blindness)
Describe the potential adverse effects of drugs on prenatal development.
-Avoid any unnecessary drugs during pregnancy
-Prescription- thalidomide tragedy (used for morning sickness, caused malformations of the fetus)
-Tabacco low birth weight, miscarriage/stillborn
-Alcohol lower birth weights and learning and behavioural difficulties. Fetal alcohol syndrome (small, heart anomalies)
Psychotropic Drugs- heroin and methadone cause miscarriage, early death. The baby also addicted to heroin
Describe how mutagenic, environmental, and epigenetic teratogens adversely affect prenatal development.
Mutagens (15-25%)
-can cause changes to DNA (chromosomal or genetic errors
Environmental agents (10%)
- can damage cells and disrupt normal cell development, and
- can interfere with cell proliferation or cell migration
Epimutagens (65%)
-cause alterations to epigenetic structures without changes to DNA such as gene silencing or expression
Identify pre-conceptual and prenatal assessment and diagnostic procedures. (i.e. CVS & Amniocentesis)
- Fathers pass of 55 genetic mutations vs. a mother is only 14.
- used to identify chromosomal and genetic disorders
CVS (chronic villus sampling)
-cells extracted from placenta
Amniocentesis
-extracts amniotic fluid containing fetal cells
Fetoscopy
- involves insertion of a tiny camera into womb directly to observe fetal development
- has made fetal blood transfustions and bone marrow transplants possible
Ctd. pg 77
Describe what happens in each of the three stages of labour.
Dilation and Effacement:
- the cervix opens and flattens out
- must dialare about 10cm
- early stage contractions are far appart
- active stage is 3-4cm till 8cm
- transition is last 2cm (strong contractions)
Delivery:
- when mother fully dialated she begins pushing
- baby goes trhough cervix to birth canal and out
- lasts less than an hr, 2 at most
Placental Delivery:
- afterbirth
- quite breif
- placenta and other material from uterus
Identify and describe assessment tools are used to assess the health of a newborn.
- Apgar scale to assess a neonate’s health immediately after birth (0/1/2 on categories like heart rate, colour and muscle tone)
- New tandem mass spectrometry tests rare metabolic disorders
- the Brazelton Neonatal Bahavioural Assesment Scale to track a newborns development over the first two week reflexes, muscle tone, alertness cuddliness
Define low birth weight and identify risks associated it.
newborn weight below 2500g (2.5kg)
Risks:
lower levels of responsiveness at birth
-respiratory distress syndrome. poorly developed lings cause serious breathing difficulties
-neurodevelopmental issues such as motor and sensory impairment, lower intelligence, more problems in school
-higher rate of learning disabilities than normal-weight peers (only in boys)
Define the following terms: synaptogenesis, neuroplasticity, myelinization
Synaptogenesis
-the process of synapse development
Neuroplasticity
-the ability of the brain to reorganize its neural structures and functioning in response to experiences
Myelinization
-a process in neuronal development in which sheaths made a substance called myelin gradually cover individual axons and electrically insulate them from one another to improve the conductivity of the nerve
Define circadian rhythm and how it affects infants
A circadian rhythm is a natural, internal process that regulates the sleep-wake cycle and repeats roughly every 24 hours.
Neonates sleep much of the time and move through a series of states of consciousness in a cycle that lasts about two hours
Most infants move from deep sleep to lighter sleep then to alert wakefullness then fussing. When their fed they get drossy and back to deep sleep. Repeat every 2hrs,
By 8wks they start to sleep through 2-3 2hr cycles without waking.
6months they sleep 13hrs more predictably
Describe how infants’ reflexes change
Adaptive reflexes
- reflexes that help newborn survive. Some adaptive relexes presist throughout life.
- include such essential responses as rotting (turning head to side to search for boob) sucking (newborns automatically start sucking on an object that enters its mouth)
Primitive reflexes
- reflexes controlled by ‘primitive’ parts of the brain that disappear during the first year of life
- include the Moro (startle) and Babunski reflexes (curl toes in when foot is stroked), which disappear within a few months.
Outline how infants’ bodies change and the typical pattern of motor skill development in the first two years. – see table 4.1 for milestones.
Bones
Increase in length of bones increase in phone number for example wrist bones separate bone hardening called ossification occurs motor development depends on ossification
Muscles
Bodies full muscle fibres present at birth although fibres are initially small and have high ratio of water to muscle And height porportion of fat
Lungs and heart
Lungs grow more rapidly become more efficient and an increase strength of heart muscles give two year olds greater stamina
Motor skills
Local motor skills age one month stepping reflex age 4 rolls over sits up with support page 7 sets without support and crawls age 10 Pulls self up and walks grasping furniture age 13 walks backwards sideways runs age 19 walks up and downstairs
Non-locomotor skills each one month let’s head slightly age 2 lifts head up to 90° each for holds had a wrecked well in sitting position age 10 squats and stoops age 13 rolls bolt adult claps age 19 jump with both feet off the ground
Discuss the health issues of infants. (Esp nutrition, immunizations, and SIDS)
Nutrition
Breast-feeding is substantially superior nutritionally to bottlefeeding for six months or more. Older mothers and immigrants are more likely to breast-feed for longer as well as western province Canadians. Breast-feeding has many benefits such as more rapid weight and size gain less likely to suffer from problems like diarrhoea Gastroenteritis bronchitis and ear infections and colic. Stimulate better immune system function. By six months infants are ready for solid foods which should include iron fortified infant single grain cereal followed by puréed fruits vegetables and finally beat or meat substitutes
Malnutrition
Macro nutrient Mal nutrition results from a diet that contains too few calories and it’s the worlds leading cause of death in children under the age of five they can suffer permanent neurological damage suffer from parasitic infections that lead to chronic diarrhoea some infants don’t contain almost enough calories but not enough protein which can lead to kwashiorkor. Some infants have poorly developed sucking reflex
Immunization
Recommended to start vaccines at two months vaccines for influenza start at age 6 and others start at the first birthday
Sudden infant death syndrome
The sudden and unexpected death of an apparently healthy infant we do not know the underlying cause but some factors have been shown to reduce risk a safe sleep environment for instants placing the baby on his back when he sleeps eliminating quilts duvets and pillows avoiding laying the baby on soft surfaces have a baby sleep in a crib avoid bed sharing and have a smoke free environment during pregnancy